Astrogenomics: big data, old problems, old solutions?

التفاصيل البيبلوغرافية
العنوان: Astrogenomics: big data, old problems, old solutions?
المؤلفون: John M. Greally, S. George Djorgovski, Aaron Golden
المصدر: Genome Biology
بيانات النشر: arXiv, 2013.
سنة النشر: 2013
مصطلحات موضوعية: media_common.quotation_subject, Astronomy, Big data, Information Dissemination, FOS: Physical sciences, Genomics, Biology, Virtual observatory, Databases, Genetic, sort, Data Mining, Humans, Quantitative Biology - Genomics, Function (engineering), Instrumentation and Methods for Astrophysics (astro-ph.IM), media_common, Genetics, Genomics (q-bio.GN), Internet, business.industry, Comment, Data science, FOS: Biological sciences, The Internet, Personalized medicine, Astrophysics - Instrumentation and Methods for Astrophysics, business, Software
الوصف: The ominous warnings of a `data deluge' in the life sciences from high-throughput DNA sequencing data are being supplanted by a second deluge, of cliches bemoaning our collective scientific fate unless we address the genomic data `tsunami'. It is imperative that we explore the many facets of the genome, not just sequence but also transcriptional and epigenetic variability, integrating these observations in order to attain a genuine understanding of how genes function, towards a goal of genomics-based personalized medicine. Determining any individual's genomic properties requires comparison to many others, sifting out the specific from the trends, requiring access to the many in order to yield information relevant to the few. This is the central big data challenge in genomics that still requires some sort of resolution. Is there a practical, feasible way of directly connecting the scientific community to this data universe? The best answer could be in the stars overhead.
Comment: 11 pages, 1 figure, accepted for publication in Genome Biology
وصف الملف: application/pdf; application/postscript
DOI: 10.48550/arxiv.1308.3277
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04bbcf3ea75f44b66e884a1635cf7712Test
حقوق: OPEN
رقم الانضمام: edsair.doi.dedup.....04bbcf3ea75f44b66e884a1635cf7712
قاعدة البيانات: OpenAIRE