Effects of Colorectal Cancer Risk Factors on the Association Between Aspirin and Colorectal Cancer
| العنوان: | Effects of Colorectal Cancer Risk Factors on the Association Between Aspirin and Colorectal Cancer |
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| المؤلفون: | Andrea C Bafford, Karen C. Johnson, Charles Kooperberg, Max Seaton, Ulrike Peters, Niha Zubair |
| المصدر: | Anticancer Res |
| بيانات النشر: | Anticancer Research USA Inc., 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Male, Cancer Research, medicine.medical_specialty, Colorectal cancer, medicine.medical_treatment, Colonoscopy, Comorbidity, Lower risk, Risk Assessment, Article, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, Internal medicine, medicine, Humans, Family history, neoplasms, Aged, Aged, 80 and over, Aspirin, medicine.diagnostic_test, business.industry, Women's Health Initiative, Anti-Inflammatory Agents, Non-Steroidal, General Medicine, Middle Aged, medicine.disease, digestive system diseases, Polypectomy, Oncology, 030220 oncology & carcinogenesis, Female, Colorectal Neoplasms, business, Risk assessment, medicine.drug |
| الوصف: | Background/aim We investigated the effect of aspirin on colorectal cancer (CRC) risk among subgroups of women with and without risk factors for CRC. Patients and methods Using data from the Women's Health Initiative, we estimated hazard ratios for CRC in association with aspirin use, with stratifications by cardiovascular disease (CVD) risk status, family history of CRC, and history of colorectal polypectomy. Results Aspirin was associated with a lower risk of CRC among women with low/normal or high CVD-risk status; no family history of CRC; or a history of colonoscopy with polypectomy. Aspirin was not associated with CRC among women with a family history of CRC or a history of colonoscopy without polypectomy. Conclusion Aspirin was associated with a lower risk of CRC in women at all levels of CVD-risk, in those with a history of colonoscopy with polypectomy, and in those without a family history of CRC. |
| تدمد: | 1791-7530 0250-7005 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::056a51b87565b5d21c57e19a98bde2c6Test https://doi.org/10.21873/anticanres.13673Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....056a51b87565b5d21c57e19a98bde2c6 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17917530 02507005 |
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