New Frontiers in Obesity Treatment: GLP-1 and Nascent Nutrient-Stimulated Hormone-Based Therapeutics
| العنوان: | New Frontiers in Obesity Treatment: GLP-1 and Nascent Nutrient-Stimulated Hormone-Based Therapeutics |
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| المؤلفون: | Ania M. Jastreboff, Robert F. Kushner |
| المصدر: | Annual Review of Medicine. 74:125-139 |
| بيانات النشر: | Annual Reviews, 2023. |
| سنة النشر: | 2023 |
| مصطلحات موضوعية: | General Medicine, General Biochemistry, Genetics and Molecular Biology |
| الوصف: | Nearly half of Americans are projected to have obesity by 2030, underscoring the pressing need for effective treatments. Glucagon-like peptide 1 receptor agonists (GLP-1 RAs) represent the first agents in a rapidly evolving, highly promising landscape of nascent hormone-based obesity therapeutics. With the understanding of the neurobiology of obesity rapidly expanding, these emerging entero-endocrine and endo-pancreatic agents combined or coformulated with GLP-1 RAs herald a new era of targeted, mechanism-based treatment of obesity. This article reviews GLP-1 RAs in the treatment of obesity and previews the imminent future of nutrient-stimulated hormone-based anti-obesity therapeutics. |
| تدمد: | 1545-326X 0066-4219 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::4cb96f036c63584dd326779415511f89Test https://doi.org/10.1146/annurev-med-043021-014919Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi...........4cb96f036c63584dd326779415511f89 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1545326X 00664219 |
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