VIRAL TRANSACTIVATING PROTEINS
| العنوان: | VIRAL TRANSACTIVATING PROTEINS |
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| المؤلفون: | Jane Flint, Thomas Shenk |
| المصدر: | Annual Review of Genetics. 31:177-212 |
| بيانات النشر: | Annual Reviews, 1997. |
| سنة النشر: | 1997 |
| مصطلحات موضوعية: | Genetics, Herpes simplex virus protein vmw65, biology, viruses, Molecular Sequence Data, Herpes Simplex Virus Protein Vmw65, E-box, Gene Products, tax, Single-stranded binding protein, Cell biology, Viral Proteins, Viral Regulatory Proteins, Cytoplasm, Transcription (biology), Bacterial transcription, Trans-Activators, biology.protein, Transcriptional regulation, Animals, Humans, Adenovirus E1A Proteins, Amino Acid Sequence |
| الوصف: | ▪ Abstract Many viruses utilize the cellular transcription apparatus to express their genomes, and they encode transcriptional regulatory proteins that modulate the process. Here we review the current understanding of three viral regulatory proteins. The adenovirus E1A protein acts within the nucleus to regulate transcription through its ability to bind to other proteins. The herpes simplex type 1 virus VP16 protein acts within the nucleus to control transcription by binding to DNA in conjunction with cellular proteins. The human T-cell leukemia virus Tax protein influences transcription through interactions with cellular proteins in the nucleus as well as the cytoplasm. |
| تدمد: | 1545-2948 0066-4197 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0e94672189f40dd3c20c9c4ce3b368bTest https://doi.org/10.1146/annurev.genet.31.1.177Test |
| رقم الانضمام: | edsair.doi.dedup.....c0e94672189f40dd3c20c9c4ce3b368b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15452948 00664197 |
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