دورية أكاديمية
La régulation de l'expression des gènes du virus de la varicelle et du zona
| العنوان: | La régulation de l'expression des gènes du virus de la varicelle et du zona |
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| المؤلفون: | Piette, Jacques, Defechereux, Patricia, Baudoux, Laurence, Melen-Lamalle, Laurence, Debrus, S., Sadzot-Delvaux, Catherine, Merville, Marie-Paule, Rentier, Bernard |
| المصدر: | Annales de Médecine Vétérinaire, 136 (8), 627-635 (1992) |
| بيانات النشر: | Annales Medecine Veterinaire |
| سنة النشر: | 1992 |
| المجموعة: | University of Liège: ORBi (Open Repository and Bibliography) |
| مصطلحات موضوعية: | Herpesvirus, Regulatory proteins, Life sciences, Biochemistry, biophysics & molecular biology, Human health sciences, Immunology & infectious disease, Sciences du vivant, Biochimie, biophysique & biologie moléculaire, Sciences de la santé humaine, Immunologie & maladie infectieuse |
| الوصف: | peer reviewed ; Varicella-zoster virus (VZV) belongs to the alphaherpesvirus family and shares many important structural and functional similarities with other members of the family such as herpes simplex virus type 1 (HSV-1). VZV is responsible for two different clinical syndromes, varicella which is the result of the primary infection and zoster which is due to virus reactivation remaining latent in the peripheral nervous system. VZV DNA is 124,884 base pair long and encodes four regulatory proteins (IE4, IE61, IE62 and IE63). Using transient expression systems, we have shown that IE4, IE62 and IE63 can regulate the expression of an indicator gene driven by various VZV promoter regions, demonstrating that these proteins play important roles in the infectious cycle. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | French |
| تدمد: | 0003-4118 1781-3875 |
| العلاقة: | urn:issn:0003-4118; urn:issn:1781-3875; https://orbi.uliege.be/handle/2268/37158Test; info:hdl:2268/37158 |
| الإتاحة: | https://orbi.uliege.be/handle/2268/37158Test |
| رقم الانضمام: | edsbas.2047DBDF |
| قاعدة البيانات: | BASE |
| تدمد: | 00034118 17813875 |
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