Percutaneous Injection of Radiopaque Gelified Ethanol for the Treatment of Lumbar and Cervical Intervertebral Disk Herniations: Experience and Clinical Outcome in 80 Patients
| العنوان: | Percutaneous Injection of Radiopaque Gelified Ethanol for the Treatment of Lumbar and Cervical Intervertebral Disk Herniations: Experience and Clinical Outcome in 80 Patients |
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| المؤلفون: | M. Ferrara, Alfonso Cerase, Irene Grazzini, C. Tabano, Sara Leonini, Pietro Piu, Daniele Giuseppe Romano, Lucia Monti, Matteo Bellini |
| المصدر: | AJNR Am J Neuroradiol |
| بيانات النشر: | American Society of Neuroradiology (ASNR), 2014. |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Percutaneous, Adolescent, Visual analogue scale, Radiography, Administration, Cutaneous, Injections, Young Adult, Lumbar, Humans, Medicine, Radiology, Nuclear Medicine and imaging, Intervertebral Disc, Aged, Pain Measurement, Aged, 80 and over, Ethanol, business.industry, Intervertebral Disc Chemolysis, Central Nervous System Depressants, Intervertebral disc, Middle Aged, Spine, Oswestry Disability Index, Surgery, Intervertebral disk, Treatment Outcome, medicine.anatomical_structure, Female, Neurology (clinical), business, Gels, Intervertebral Disc Displacement |
| الوصف: | BACKGROUND AND PURPOSE: Chemonucleolysis represents a minimally invasive percutaneous technique characterized by an intradiskal injection of materials under fluoroscopic or CT guidance. Recently, a substance based on radiopaque gelified ethanol has been introduced. The purpose of this study was to describe the indications, procedure, safety, and efficacy of radiopaque gelified ethanol in the percutaneous treatment of cervical and lumbar disk herniations. MATERIALS AND METHODS: Between September 2010 and August 2013, 80 patients (32 women and 48 men; age range, 18–75 years) were treated for 107 lumbar disk herniations (L2–L3, n = 1; L3–L4, n = 15; L4–L5, n = 53; and L5–S1, n = 38) and 9 cervical disk herniations (C4–C5, n = 2; C5–C6, n = 2; C6–C7, n = 3; and C7–D1, n = 2) by percutaneous intradiskal injection of radiopaque gelified ethanol under fluoroscopic guidance. Thirty-six patients underwent a simultaneous treatment of 2 disk herniations. Patient symptoms were resistant to conservative therapy, with little or no pain relief after 4–6 weeks of physical therapy and drugs. All patients were evaluated by the Visual Analog Scale and the Oswestry Disability Index. RESULTS: Sixty-two of 73 (85%) patients with lumbar disk herniations and 6/7 (83%) patients with cervical disk herniations obtained significant symptom improvement, with a Visual Analog Scale reduction of at least 4 points and an Oswestry Disability Index reduction of at least 40%. Leakage of radiopaque gelified ethanol in the surrounding tissues occurred in 19 patients, however without any clinical side effects. CONCLUSIONS: In our experience, percutaneous intradiskal injection of radiopaque gelified ethanol is safe and effective in reducing the period of recovery from disabling symptoms. |
| تدمد: | 1936-959X 0195-6108 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5828800ebede5b9a1b93f456b4a06eaTest https://doi.org/10.3174/ajnr.a4166Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....c5828800ebede5b9a1b93f456b4a06ea |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1936959X 01956108 |
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