التفاصيل البيبلوغرافية
العنوان: |
β2-integrin activity: the role of thiols. |
المؤلفون: |
Zarbock, Alexander1 |
المصدر: |
Blood. 5/9/2013, Vol. 121 Issue 19, p3779-3780. 2p. |
مصطلحات موضوعية: |
*PROTEIN disulfide isomerase, *INTEGRINS, *NEUTROPHILS, *MACROPHAGE-1 antigen, *INFLAMMATION |
مستخلص: |
The author discusses the study by E. Hahm and colleagues on the extracellular protein disulfide isomerase (PDI) as an important regulator of β2-integrin macrophage-1 antigen (Mac-1) adhesiveness on neutrophils. He says that the study shows a new mechanism by which β2-integrin Mac-1 adhesiveness can be regulated under inflammatory conditions. He mentions that the findings of the study play an important role for PDI in neutrophil regulation during inflammation. |
قاعدة البيانات: |
Academic Search Index |