نتائج البحث

1

Cytokine-like protein 1–induced survival of monocytes suggests a combined strategy targeting MCL1 and MAPK in CMML

المساهمون: Institut d'Histoire et de Philosophie des Sciences et des Techniques (IHPST), Université Paris 1 Panthéon-Sorbonne (UP1)-Centre National de la Recherche Scientifique (CNRS)

المصدر: Blood
Blood, American Society of Hematology, 2021, 137 (24), pp.3390-3402. ⟨10.1182/blood.2020008729⟩

مصطلحات موضوعية: Adult, Male, MAPK/ERK pathway, CCR2, Myeloid, Cell Survival, MAP Kinase Signaling System, [SDV]Life Sciences [q-bio], Immunology, Chronic myelomonocytic leukemia, Biochemistry, Monocytes, 03 medical and health sciences, Chemokine receptor, 0302 clinical medicine, hemic and lymphatic diseases, medicine, Humans, MCL1, Extracellular Signal-Regulated MAP Kinases, Autocrine signalling, Protein Kinase Inhibitors, Aged, 030304 developmental biology, Aged, 80 and over, 0303 health sciences, Kinase, Chemistry, [SHS.PHIL]Humanities and Social Sciences/Philosophy, Leukemia, Myelomonocytic, Chronic, Blood Proteins, Cell Biology, Hematology, Middle Aged, medicine.disease, Xenograft Model Antitumor Assays, 3. Good health, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Cancer research, Cytokines, Myeloid Cell Leukemia Sequence 1 Protein, Female

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5a876fc49ce5e247d9cb91a3a300a22Test
https://doi.org/10.1182/blood.2020008729Test

2

Secreted modular calcium-binding protein 1 binds and activates thrombin to account for platelet hyperreactivity in diabetes

المؤلفون: Dagmar Meyer zu Heringdorf, Corina Ratiu, Amro Elgheznawy, Voahanginirina Randriamboavonjy, Anastasia Kyselova, Ingrid Fleming, Mauro Siragusa, Alexander W. Mann, Beate Fisslthaler, Fredy Delgado Lagos

المصدر: Blood. 137:1641-1651

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bcf0b32aeb935a44038d5325894fca8Test
https://doi.org/10.1182/blood.2020009405Test

3

Targeting aberrant DNA hypermethylation as a driver of ATL leukemogenesis by using the new oral demethylating agent OR-2100

المؤلفون: Satoshi Yamashita, Naoko Hattori, Yuki Kurahashi, Toshikazu Ushijima, Naoko Sueoka-Aragane, Tatsuro Watanabe, Akemi Sato, Kensuke Kojima, Hideaki Nakamura, Atsushi Kawaguchi, Shinya Kimura, Eisaburo Sueoka, Nao Yoshida, Kazuharu Kamachi, Seiji Okada, Hiroshi Ureshino, Yuki Fukuda-Kurahashi

المصدر: Blood. 136:871-884

مصطلحات موضوعية: Adult, 0301 basic medicine, Pyridines, viruses, Immunology, Administration, Oral, Decitabine, Antineoplastic Agents, Biology, Biochemistry, Mice, Young Adult, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, immune system diseases, hemic and lymphatic diseases, medicine, Animals, Humans, Leukemia-Lymphoma, Adult T-Cell, Molecular Targeted Therapy, Cells, Cultured, Aged, Mice, Knockout, Regulation of gene expression, Human T-lymphotropic virus 1, Mice, Inbred BALB C, Gene Expression Regulation, Leukemic, Cell growth, T-cell receptor, Drugs, Investigational, Cell Biology, Hematology, DNA Methylation, Cell Transformation, Viral, HTLV-I Infections, Xenograft Model Antitumor Assays, Demethylation, Demethylating agent, 030104 developmental biology, chemistry, Cell culture, 030220 oncology & carcinogenesis, DNA methylation, Cancer research, Female, medicine.drug, DNA hypomethylation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30f0e7224c117c25f69a987a740a43e5Test
https://doi.org/10.1182/blood.2019003084Test

4

A randomized double-blind trial of 3 aspirin regimens to optimize antiplatelet therapy in essential thrombocythemia

المصدر: Blood. 136:171-182

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2745a074f0e9fb3a40b7e799bc767c0Test
https://doi.org/10.1182/blood.2019004596Test

5

Successful donor engraftment and repair of the blood-brain barrier in cerebral adrenoleukodystrophy

المؤلفون: Ashish Gupta, Paul J. Orchard, Troy C. Lund, Daniel L. Kenney-Jung, Weston P. Miller, David Nascene

المصدر: Blood. 133:1378-1381

مصطلحات موضوعية: Adult, Graft Rejection, Male, 0301 basic medicine, Pathology, medicine.medical_specialty, Myeloid, Adolescent, medicine.medical_treatment, Gadolinium, Immunology, Central nervous system, chemistry.chemical_element, Hematopoietic stem cell transplantation, Blood–brain barrier, ATP Binding Cassette Transporter, Subfamily D, Member 1, Biochemistry, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Humans, Medicine, Adrenoleukodystrophy, Child, business.industry, Graft Survival, Hematopoietic Stem Cell Transplantation, Biological Transport, Cell Biology, Hematology, Middle Aged, Peroxisome, Prognosis, medicine.disease, Tissue Donors, Transplantation, 030104 developmental biology, medicine.anatomical_structure, chemistry, Blood-Brain Barrier, Child, Preschool, Mutation, Disease Progression, business, 030217 neurology & neurosurgery, Follow-Up Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d100c06f6ac59fd39ac4194fe0eb15Test
https://doi.org/10.1182/blood-2018-11-887240Test

6

The platelet NLRP3 inflammasome is upregulated in sickle cell disease via HMGB1/TLR4 and Bruton tyrosine kinase

المؤلفون: Sebastian Vogel, Swee Lay Thein, Zenaide M.N. Quezado, James S. Nichols, Taruna Arora, Laurel Mendelsohn, Xunde Wang, Arun S. Shet, Darlene Allen, Christian A. Combs

المصدر: Blood Advances. 2:2672-2680

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, medicine.medical_specialty, Inflammasomes, Caspase 1, Context (language use), Anemia, Sickle Cell, Mice, 03 medical and health sciences, chemistry.chemical_compound, hemic and lymphatic diseases, Internal medicine, NLR Family, Pyrin Domain-Containing 3 Protein, Agammaglobulinaemia Tyrosine Kinase, Animals, Humans, Medicine, Bruton's tyrosine kinase, Platelet, HMGB1 Protein, Receptor, integumentary system, biology, business.industry, Inflammasome, Hematology, Middle Aged, Platelets and Thrombopoiesis, Up-Regulation, Toll-Like Receptor 4, 030104 developmental biology, Endocrinology, chemistry, Ibrutinib, biology.protein, TLR4, Female, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26406e723e23bfe96d742ca16d17b5e5Test
https://doi.org/10.1182/bloodadvances.2018021709Test

7

Cotargeting BCL-2 and MCL-1 in high-risk B-ALL

المصدر: Blood Adv

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e036a8f464807723f471eb56cdde76cTest
https://europepmc.org/articles/PMC7322969Test/

8

Syk inhibitors interfere with erythrocyte membrane modification during P falciparum growth and suppress parasite egress

المؤلفون: Evelin Schwarzer, Ioannis Tsamesidis, Maria Carmina Pau, Kristina R. Kesely, Oleksii A. Skorokhod, Lucia Bertuccini, Marta Ponzi, Francesco Michelangelo Turrini, Antonella Pantaleo, Philip S. Low, Huynh Dinh Chien

المصدر: Blood

مصطلحات موضوعية: Falciparum, Adult, Male, 0301 basic medicine, Erythrocytes, Immunology, Plasmodium falciparum, Syk, Biology, Biochemistry, Animals, Anion Exchange Protein 1, Erythrocyte, Cell Differentiation, Erythrocyte Membrane, Female, Humans, Inhibitory Concentration 50, Malaria, Falciparum, Parasites, Phosphorylation, Protein Kinase Inhibitors, Syk Kinase, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Red Cells, Iron, and Erythropoiesis, Spectrin, Tyrosine, Anion Exchange Protein 1, Tyrosine phosphorylation, Cell Biology, Hematology, biology.organism_classification, Actin cytoskeleton, Cell biology, Malaria, Erythrocyte, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, Tyrosine kinase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2fe95d5e4e956917fe1028f70daa643Test
https://europepmc.org/articles/PMC8939463Test/

9

Serum hepcidin: reference ranges and biochemical correlates in the general population

المؤلفون: Tessel E. Galesloot, Lambertus A. Kiemeney, Joyce J.C. Kroot, Dorlene van Tienoven, Jack F.M. Wetzels, Martin den Heijer, Dorine W. Swinkels, Sita H. Vermeulen, Fred C. G. J. Sweep, Siem M. Klaver, Anneke Geurts-Moespot

المصدر: Blood, 117, e218-25
Blood, 117, 25, pp. e218-25

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Immunology, Population, Iron metabolism Pathogenesis and modulation of inflammation [IGMD 7], Renal function, Enzyme-Linked Immunosorbent Assay, Molecular epidemiology Iron metabolism [NCEBP 1], Biochemistry, Molecular epidemiology [NCEBP 1], chemistry.chemical_compound, Sex Factors, Hepcidins, Reference Values, Total iron-binding capacity, Hepcidin, Internal medicine, Iron metabolism [IGMD 7], Humans, Medicine, education, Molecular epidemiology Aetiology, screening and detection [NCEBP 1], Renal disorder [IGMD 9], Aged, Aged, 80 and over, Creatinine, education.field_of_study, biology, medicine.diagnostic_test, business.industry, Hormonal regulation [IGMD 6], C-reactive protein, Age Factors, Cell Biology, Hematology, Middle Aged, Confidence interval, Ferritin, Endocrinology, chemistry, Multivariate Analysis, Linear Models, biology.protein, Hormonal regulation Aetiology, screening and detection [IGMD 6], Female, business, Antimicrobial Cationic Peptides

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8d5795079b07f6976b8942f008cade8Test
https://doi.org/10.1182/blood-2011-02-337907Test

10

Human circadian system causes a morning peak in prothrombotic plasminogen activator inhibitor-1 (PAI-1) independent of the sleep/wake cycle

المؤلفون: Frank A.J.L. Scheer, Steven Shea

المصدر: Blood. 123:590-593

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e48a5e7c7bf79f76d59589a69a8d3b64Test
https://doi.org/10.1182/blood-2013-07-517060Test

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