نتائج البحث

1

Cancer Susceptibility Gene Mutations in Individuals With Colorectal Cancer

المؤلفون: Hajime Uno, Jeffrey A. Meyerhardt, Jason L. Hornick, Matthew B. Yurgelun, Nanda Singh, Brian Allen, Matthew H. Kulke, Richard J. Wenstrup, Philip G. McNamara, Anne-Renee Hartman, Robert J. Mayer, Deborah Schrag, Lauren K. Brais, John Kidd, Sapna Syngal, Kimmie Ng, Chinedu Ukaegbu, Charles S. Fuchs

المصدر: Journal of Clinical Oncology. 35:1086-1095

مصطلحات موضوعية: Male, 0301 basic medicine, Oncology, Cancer Research, Colorectal cancer, DNA Mutational Analysis, Genes, BRCA2, Genes, BRCA1, Penetrance, Germline, DNA Glycosylases, 0302 clinical medicine, Family history, Mismatch Repair Endonuclease PMS2, Aged, 80 and over, Genetics, Nuclear Proteins, ORIGINAL REPORTS, Middle Aged, Epithelial Cell Adhesion Molecule, Lynch syndrome, DNA-Binding Proteins, MutS Homolog 2 Protein, 030220 oncology & carcinogenesis, Female, Colorectal Neoplasms, Fanconi Anemia Complementation Group N Protein, MutL Protein Homolog 1, Adult, medicine.medical_specialty, Adenomatous Polyposis Coli Protein, Young Adult, 03 medical and health sciences, Germline mutation, Internal medicine, medicine, Humans, Genetic Predisposition to Disease, Germ-Line Mutation, Aged, business.industry, Genes, p16, Tumor Suppressor Proteins, Microsatellite instability, Cancer, medicine.disease, Colorectal Neoplasms, Hereditary Nonpolyposis, digestive system diseases, Checkpoint Kinase 2, 030104 developmental biology, Tumor Suppressor Protein p53, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5185111baac1b51ca8d1fa882da0b09eTest
https://doi.org/10.1200/jco.2016.71.0012Test

2

Combined Microsatellite Instability, MLH1 Methylation Analysis, and Immunohistochemistry for Lynch Syndrome Screening in Endometrial Cancers From GOG210: An NRG Oncology and Gynecologic Oncology Group Study

المصدر: Journal of Clinical Oncology

مصطلحات موضوعية: Oncology, Cancer Research, DNA Mismatch Repair, 0302 clinical medicine, Early Detection of Cancer, Mismatch Repair Endonuclease PMS2, Adenosine Triphosphatases, Gynecologic Cancer, 0303 health sciences, Age Factors, Nuclear Proteins, Gync13, ORIGINAL REPORTS, Middle Aged, Immunohistochemistry, Lynch syndrome, Pedigree, 3. Good health, DNA-Binding Proteins, Gene Expression Regulation, Neoplastic, MutS Homolog 2 Protein, Population Surveillance, 030220 oncology & carcinogenesis, DNA methylation, Female, Microsatellite Instability, DNA mismatch repair, MutL Protein Homolog 1, Adult, congenital, hereditary, and neonatal diseases and abnormalities, medicine.medical_specialty, Gynecologic oncology, MLH1, 03 medical and health sciences, Germline mutation, Predictive Value of Tests, Internal medicine, medicine, Humans, Genetic Testing, neoplasms, Germ-Line Mutation, Adaptor Proteins, Signal Transducing, Aged, 030304 developmental biology, business.industry, Endometrial cancer, nutritional and metabolic diseases, Microsatellite instability, DNA Methylation, medicine.disease, Colorectal Neoplasms, Hereditary Nonpolyposis, digestive system diseases, Endometrial Neoplasms, DNA Repair Enzymes, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a44494338fe2ed97a8c308f7181cc8aTest
https://doi.org/10.1200/jco.2015.63.9518Test

3

Colorectal and Other Cancer Risks for Carriers and Noncarriers From Families With a DNA Mismatch Repair Gene Mutation: A Prospective Cohort Study

المصدر: Journal of Clinical Oncology. 30:958-964

مصطلحات موضوعية: Adult, Male, Oncology, Heterozygote, Cancer Research, medicine.medical_specialty, Colorectal cancer, Gene mutation, DNA Mismatch Repair, Breast cancer, Risk Factors, Neoplasms, Internal medicine, Original Reports, medicine, Humans, Genetic Predisposition to Disease, Prospective Studies, Prospective cohort study, Adaptor Proteins, Signal Transducing, Aged, Mismatch Repair Endonuclease PMS2, Adenosine Triphosphatases, Aged, 80 and over, business.industry, Incidence, Australia, Nuclear Proteins, Cancer, Middle Aged, Prognosis, medicine.disease, Lynch syndrome, Surgery, DNA-Binding Proteins, Survival Rate, MSH6, DNA Repair Enzymes, MutS Homolog 2 Protein, MSH2, Mutation, Female, Colorectal Neoplasms, MutL Protein Homolog 1, business, Follow-Up Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3352b9be7b5edeb55dc3e09412c48146Test
https://doi.org/10.1200/jco.2011.39.5590Test

4

Molecular Profiling Identifies Prognostic Subgroups of Pediatric Glioblastoma and Shows Increased YB-1 Expression in Tumors

المصدر: Journal of Clinical Oncology. 25:1196-1208

مصطلحات موضوعية: Male, Cancer Research, Pathology, Gene Expression, Apoptosis, Polymerase Chain Reaction, Gene expression, Phosphorylation, Child, Aged, 80 and over, Brain Neoplasms, Brain, Nuclear Proteins, Middle Aged, Prognosis, Immunohistochemistry, Phenotype, DNA-Binding Proteins, ErbB Receptors, Oncology, Child, Preschool, Female, Signal transduction, Signal Transduction, Adult, medicine.medical_specialty, Adolescent, Brain tumor, methods, Proto-Oncogene Proteins p21(ras), Proto-Oncogene Proteins, medicine, pharmaceutical, Humans, genome, Gene, PI3K/AKT/mTOR pathway, Aged, Epidermal Growth Factor, business.industry, Protein, Gene Expression Profiling, Proteins, Infant, medicine.disease, Gene expression profiling, Genes, Cancer research, Y-Box-Binding Protein 1, Glioblastoma, business, Proto-Oncogene Proteins c-akt

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03df64689fcb85e74062e45d25ddd86aTest
https://doi.org/10.1200/jco.2006.07.8626Test

5

Lower Incidence of Colorectal Cancer and Later Age of Disease Onset in 27 Families With Pathogenic MSH6 Germline Mutations Compared With Families With MLH1 or MSH2 Mutations: The German Hereditary Nonpolyposis Colorectal Cancer Consortium

المؤلفون: Josef Rüschoff, Markus Loeffler, Stefan Krüger, Karsten Schulmann, Christoph Engel, Johannes Gebert, Constanze Pagenstecher, Jens Plaschke, Magnus von Knebel Doeberitz, Elke Holinski-Feder, Hans K. Schackert, Elisabeth Mangold, Gabriela Moeslein

المصدر: Journal of Clinical Oncology. 22:4486-4494

مصطلحات موضوعية: Adult, Male, Oncology, congenital, hereditary, and neonatal diseases and abnormalities, Cancer Research, medicine.medical_specialty, DNA Repair, Base Pair Mismatch, Colorectal cancer, medicine.disease_cause, MLH1, Gastroenterology, Germline, Germline mutation, Risk Factors, Proto-Oncogene Proteins, Internal medicine, medicine, Humans, Genetic Predisposition to Disease, Age of Onset, neoplasms, Germ-Line Mutation, Adaptor Proteins, Signal Transducing, Aged, Mutation, business.industry, Incidence, Nuclear Proteins, nutritional and metabolic diseases, Middle Aged, medicine.disease, Colorectal Neoplasms, Hereditary Nonpolyposis, Immunohistochemistry, digestive system diseases, Endometrial Neoplasms, Neoplasm Proteins, DNA-Binding Proteins, MSH6, MutS Homolog 2 Protein, Phenotype, MSH2, Female, Age of onset, Carrier Proteins, MutL Protein Homolog 1, business, Microsatellite Repeats

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22fbfad022f5ee638c837e9fe841df9dTest
https://doi.org/10.1200/jco.2004.02.033Test

6

Individuals With an Increased Risk of Colorectal Cancer: Perceived Benefits and Psychological Aspects of Surveillance by Means of Regular Colonoscopies

المؤلفون: Samuel Rotstein, Bo Nilsson, Annelie Liljegren, Thomas Hatschek, Annika Lindblom, Yvonne Brandberg, E Jaramillo, G. Lindgren

المصدر: Journal of Clinical Oncology. 22:1736-1742

مصطلحات موضوعية: Adult, Male, Cancer Research, medicine.medical_specialty, Colorectal cancer, Cross-sectional study, Genetic counseling, DNA Mutational Analysis, Colonoscopy, Genetic Counseling, Anxiety, Hospital Anxiety and Depression Scale, Gastroenterology, Risk Factors, Proto-Oncogene Proteins, Internal medicine, medicine, Humans, Genetic Predisposition to Disease, Patient participation, Risk factor, Depression (differential diagnoses), Adaptor Proteins, Signal Transducing, medicine.diagnostic_test, Depression, business.industry, Nuclear Proteins, Middle Aged, medicine.disease, Neoplasm Proteins, DNA-Binding Proteins, Cross-Sectional Studies, MutS Homolog 2 Protein, Oncology, Population Surveillance, Family medicine, Female, Perception, Patient Participation, Carrier Proteins, Colorectal Neoplasms, MutL Protein Homolog 1, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53265806a4e9d20be799d7612144ead2Test
https://doi.org/10.1200/jco.2004.04.138Test

7

Mutations of hMLH1 and hMSH2 in Patients With Suspected Hereditary Nonpolyposis Colorectal Cancer: Correlation With Microsatellite Instability and Abnormalities of Mismatch Repair Protein Expression

المؤلفون: Italo Bearzi, Mario Scartozzi, Emilio Porfiri, S. Rosati, Cristian Loretelli, Eva Galizia, Francesca Bianchi, Andrea Piga, Riccardo Cellerino, Annalisa Antolini

المصدر: Journal of Clinical Oncology. 20:1203-1208

مصطلحات موضوعية: Adult, Male, Oncology, congenital, hereditary, and neonatal diseases and abnormalities, Cancer Research, medicine.medical_specialty, Pathology, DNA Repair, Colorectal cancer, Gene mutation, medicine.disease_cause, Proto-Oncogene Proteins, Internal medicine, medicine, Humans, Missense mutation, neoplasms, Adaptor Proteins, Signal Transducing, Aged, Genetic testing, Mutation, medicine.diagnostic_test, business.industry, Nuclear Proteins, nutritional and metabolic diseases, Microsatellite instability, Mismatch Repair Protein, Middle Aged, medicine.disease, Colorectal Neoplasms, Hereditary Nonpolyposis, Immunohistochemistry, digestive system diseases, Neoplasm Proteins, DNA-Binding Proteins, MutS Homolog 2 Protein, Female, DNA mismatch repair, Carrier Proteins, Colorectal Neoplasms, MutL Protein Homolog 1, business, Microsatellite Repeats

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88251153c0e84708e7e9c4297ad027f1Test
https://doi.org/10.1200/jco.2002.20.5.1203Test

8

Reduced MLH1 Expression in Breast Tumors After Primary Chemotherapy Predicts Disease-Free Survival

المؤلفون: Melanie Mackean, James Paul, Stan B. Kaye, Robert S. Brown, David Cameron, H.J. Mackay, M. Rahilly

المصدر: Journal of Clinical Oncology. 18:87-87

مصطلحات موضوعية: Adult, Oncology, Cancer Research, medicine.medical_specialty, Tumor suppressor gene, Base Pair Mismatch, medicine.medical_treatment, Mammary gland, Antineoplastic Agents, Breast Neoplasms, Disease-Free Survival, Statistics, Nonparametric, Metastasis, Breast cancer, Internal medicine, medicine, Carcinoma, Humans, Lymph node, Adaptor Proteins, Signal Transducing, Aged, Retrospective Studies, Likelihood Functions, Chemotherapy, business.industry, Nuclear Proteins, Middle Aged, Prognosis, medicine.disease, Neoplasm Proteins, medicine.anatomical_structure, Drug Resistance, Neoplasm, Cancer research, Regression Analysis, Immunohistochemistry, Female, Tumor Suppressor Protein p53, Carrier Proteins, MutL Protein Homolog 1, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::001a800ea39bf92885f892e7547fb62eTest
https://doi.org/10.1200/jco.2000.18Test.1.87

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