نتائج البحث

1

Pembrolizumab Plus Ipilimumab Following Anti-PD-1/L1 Failure in Melanoma

المصدر: J Clin Oncol

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f53f50387d5994f75ceeba750e8bc2f9Test
https://doi.org/10.1200/jco.21.00079Test

2

Lesion-Level Response Dynamics to Programmed Cell Death Protein (PD-1) Blockade

المؤلفون: Andrew J. Plodkowski, Dung T. Le, Juan C. Osorio, Jennifer N. Durham, Hira Rizvi, Helena A. Yu, Michelle S. Ginsberg, Gregory J. Riely, Jamie E. Chaft, Luis A. Diaz, Peter Sawan, Joseph G. Crompton, Azadeh Namakydoust, Kathryn C. Arbour, Matthew D. Hellmann, Darragh Halpenny, Barzin Y. Nabet

المصدر: J Clin Oncol

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3125b25bfcd71b2f7f4627b1e329400Test
https://doi.org/10.1200/jco.19.00709Test

3

Pivotal Trial of Enfortumab Vedotin in Urothelial Carcinoma After Platinum and Anti-Programmed Death 1/Programmed Death Ligand 1 Therapy

المؤلفون: Peter H. O'Donnell, Noah M. Hahn, Elaina M. Gartner, Matthew D. Galsky, Shang Ying Liang, Daniel P. Petrylak, Amal Melhem-Bertrandt, Evan Y. Yu, Juan Pinelli, Arjun Vasant Balar, Elisabeth I. Heath, Bradley Alexander McGregor, Jonathan E. Rosenberg

المصدر: Journal of Clinical Oncology. 37:2592-2600

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aefe6525295831e1855f0719124b2cdTest
https://doi.org/10.1200/jco.19.01140Test

4

Efficacy, Safety, and Correlative Biomarkers of Toripalimab in Previously Treated Recurrent or Metastatic Nasopharyngeal Carcinoma: A Phase II Clinical Trial (POLARIS-02)

المؤلفون: Ye Chen, Lin Shen, Shujun Yang, Xiao-Li Wei, Sheng Yao, Xichun Hu, Xianglin Yuan, Yi Jiang, Haixin Huang, Qi Li, Yongqian Shu, Rui-Hua Xu, Xiaoyan Lin, Guanghai Dai, Fenghua Wang, Qingyuan Zhang, Weifeng Wang, Hai Wu, Hui Feng, Yunpeng Liu, Jifeng Feng, Wangjun Liao, Jianhua Shi, Nong Xu

المصدر: Journal of Clinical Oncology. 39:704-712

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Oncology, China, Herpesvirus 4, Human, Cancer Research, medicine.medical_specialty, Time Factors, Immune checkpoint inhibitors, Programmed Cell Death 1 Receptor, Antibodies, Monoclonal, Humanized, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Humans, Medicine, Prospective Studies, Progression-free survival, Prospective cohort study, Immune Checkpoint Inhibitors, Aged, Nasopharyngeal Carcinoma, Proto-Oncogene Proteins c-ets, business.industry, Chromosomes, Human, Pair 11, Nasopharyngeal Neoplasms, Middle Aged, Viral Load, medicine.disease, Progression-Free Survival, Repressor Proteins, Clinical trial, 030104 developmental biology, Nasopharyngeal carcinoma, 030220 oncology & carcinogenesis, DNA, Viral, Monoclonal, Disease Progression, Female, Neoplasm Recurrence, Local, Previously treated, business, Viral load

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d5865b9a71fcd25db5548dea278cc7aTest
https://doi.org/10.1200/jco.20.02712Test

5

Salvage Ipilimumab and Nivolumab in Patients With Metastatic Renal Cell Carcinoma After Prior Immune Checkpoint Inhibitors

المؤلفون: Brian I. Rini, Ying Long, Charlene Mantia, Michael B. Atkins, Tyler F. Stewart, Moshe Chaim Ornstein, Neil J. Shah, Emily Stern Gatof, Hans J. Hammers, Michael E. Hurwitz, Anita Gul, David F. McDermott, Kimberly D Allman

المصدر: Journal of Clinical Oncology. 38:3088-3094

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Immune checkpoint inhibitors, Programmed Cell Death 1 Receptor, Salvage therapy, Ipilimumab, B7-H1 Antigen, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Renal cell carcinoma, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, Carcinoma, medicine, Humans, In patient, Progression-free survival, Carcinoma, Renal Cell, Immune Checkpoint Inhibitors, Aged, Retrospective Studies, Aged, 80 and over, Salvage Therapy, business.industry, Middle Aged, medicine.disease, Kidney Neoplasms, Progression-Free Survival, Nivolumab, 030104 developmental biology, 030220 oncology & carcinogenesis, Retreatment, Disease Progression, Female, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8edc31be2f2acfc6e054e39b50a66dfbTest
https://doi.org/10.1200/jco.19.03315Test

6

Randomized, Open-Label Phase II Study Evaluating the Efficacy and Safety of Talimogene Laherparepvec in Combination With Ipilimumab Versus Ipilimumab Alone in Patients With Advanced, Unresectable Melanoma

المؤلفون: Céleste Lebbé, Merrick I. Ross, Axel Hauschild, Theodore F. Logan, Robert H.I. Andtbacka, John A. Glaspy, Philip Friedlander, Claus Garbe, Jason Chesney, Omid Hamid, Howard L. Kaufman, Parminder Singh, Jenny J. Kim, Frances A. Collichio, Jennifer Gansert, Mohammed M. Milhem, Lisa Chen, Igor Puzanov

المصدر: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, vol 36, iss 17

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Skin Neoplasms, Phases of clinical research, Herpesvirus 1, Human, Gastroenterology, law.invention, 0302 clinical medicine, Randomized controlled trial, law, Antineoplastic Combined Chemotherapy Protocols, 80 and over, Clinical endpoint, Medicine, Melanoma, 6.2 Cellular and gene therapies, Cancer, Aged, 80 and over, Middle Aged, Progression-Free Survival, Oncology, Rapid Communications, 030220 oncology & carcinogenesis, Female, Chills, medicine.symptom, Talimogene laherparepvec, Human, medicine.drug, Proto-Oncogene Proteins B-raf, Adult, medicine.medical_specialty, Clinical Trials and Supportive Activities, Clinical Sciences, Oncology and Carcinogenesis, Ipilimumab, Young Adult, 03 medical and health sciences, Clinical Research, Internal medicine, Genetics, Humans, Oncology & Carcinogenesis, Progression-free survival, Neoplasm Staging, Aged, Biological Products, Herpesvirus 1, business.industry, Evaluation of treatments and therapeutic interventions, medicine.disease, Surgery, 030104 developmental biology, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8badceef0af92ffd8b3a736c40a1376Test
https://doi.org/10.1200/jco.2017.73.7379Test

7

Comprehensive Paired Tumor/Germline Testing for Lynch Syndrome: Bringing Resolution to the Diagnostic Process

المصدر: Journal of Clinical Oncology

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Genetic Testing for Cancer, DNA Mutational Analysis, Germline, 03 medical and health sciences, 0302 clinical medicine, Predictive Value of Tests, Internal medicine, Biomarkers, Tumor, medicine, Humans, Genetic Predisposition to Disease, Promoter Regions, Genetic, Germ-Line Mutation, Aged, Retrospective Studies, business.industry, Reproducibility of Results, Diagnostic test, ORIGINAL REPORTS, DNA Methylation, Middle Aged, medicine.disease, Colorectal Neoplasms, Hereditary Nonpolyposis, Lynch syndrome, Endometrial Neoplasms, 030104 developmental biology, 030220 oncology & carcinogenesis, Female, Microsatellite Instability, MutL Protein Homolog 1, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd3843d83c1490e469a734034178320bTest
https://doi.org/10.1200/jco.18.00696Test

8

Clinical and Genetic Risk Prediction of Subsequent CNS Tumors in Survivors of Childhood Cancer: A Report From the COG ALTE03N1 Study

المؤلفون: Joseph P. Neglia, Melissa M. Hudson, Xuexia Wang, Wendy Landier, Kandice Smith, Kevin C. Oeffinger, Doojduen Villaluna, Leo Mascarenhas, Douglas S. Hawkins, Can-Lan Sun, Leslie L. Robison, Lindsey Hageman, A. Kim Ritchey, Smita Bhatia, Purnima Singh, Sunil Desai

المصدر: Journal of Clinical Oncology. 35:3688-3696

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Neoplasms, Radiation-Induced, Adolescent, Genes, BRCA2, Childhood cancer, Single-nucleotide polymorphism, LIG4, Polymorphism, Single Nucleotide, Risk Assessment, Central Nervous System Neoplasms, DNA Ligase ATP, 03 medical and health sciences, XRCC1, 0302 clinical medicine, Cog, Risk Factors, Neoplasms, Internal medicine, medicine, Genetic predisposition, Humans, Genetic Predisposition to Disease, DNA Polymerase III, POLD1, business.industry, Age Factors, ORIGINAL REPORTS, Endonucleases, DNA-Binding Proteins, X-ray Repair Cross Complementing Protein 1, 030104 developmental biology, Adult Survivors of Child Adverse Events, Case-Control Studies, 030220 oncology & carcinogenesis, Immunology, Female, Tumor Suppressor Protein p53, ERCC1, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42c5e826488e9418b202d6febf36af25Test
https://doi.org/10.1200/jco.2017.74.7444Test

9

Multigene Panel Testing Provides a New Perspective on Lynch Syndrome

المؤلفون: Heather Hampel, Chia-Ling Gau, Holly LaDuca, Shuwei Li, Rachel McFarland, Carin R. Espenschied

المصدر: J Clin Oncol

مصطلحات موضوعية: Male, 0301 basic medicine, Oncology, Cancer Research, DNA Mutational Analysis, Genes, BRCA2, Genes, BRCA1, DNA Mismatch Repair, 0302 clinical medicine, Child, Mismatch Repair Endonuclease PMS2, Aged, 80 and over, Genetics, education.field_of_study, DNA, Neoplasm, ORIGINAL REPORTS, Middle Aged, Epithelial Cell Adhesion Molecule, Lynch syndrome, DNA-Binding Proteins, MutS Homolog 2 Protein, Phenotype, 030220 oncology & carcinogenesis, Female, MutL Protein Homolog 1, Adult, congenital, hereditary, and neonatal diseases and abnormalities, medicine.medical_specialty, Adolescent, Population, Breast Neoplasms, MLH1, Risk Assessment, Young Adult, 03 medical and health sciences, Breast cancer, Internal medicine, medicine, Humans, Genetic Testing, education, neoplasms, Aged, Retrospective Studies, business.industry, Endometrial cancer, nutritional and metabolic diseases, Cancer, medicine.disease, Colorectal Neoplasms, Hereditary Nonpolyposis, digestive system diseases, MSH6, 030104 developmental biology, MSH2, Mutation, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3cdd3ad78774f5e9984812354f3c7c0Test
https://doi.org/10.1200/jco.2016.71.9260Test

10

Cancer Susceptibility Gene Mutations in Individuals With Colorectal Cancer

المؤلفون: Hajime Uno, Jeffrey A. Meyerhardt, Jason L. Hornick, Matthew B. Yurgelun, Nanda Singh, Brian Allen, Matthew H. Kulke, Richard J. Wenstrup, Philip G. McNamara, Anne-Renee Hartman, Robert J. Mayer, Deborah Schrag, Lauren K. Brais, John Kidd, Sapna Syngal, Kimmie Ng, Chinedu Ukaegbu, Charles S. Fuchs

المصدر: Journal of Clinical Oncology. 35:1086-1095

مصطلحات موضوعية: Male, 0301 basic medicine, Oncology, Cancer Research, Colorectal cancer, DNA Mutational Analysis, Genes, BRCA2, Genes, BRCA1, Penetrance, Germline, DNA Glycosylases, 0302 clinical medicine, Family history, Mismatch Repair Endonuclease PMS2, Aged, 80 and over, Genetics, Nuclear Proteins, ORIGINAL REPORTS, Middle Aged, Epithelial Cell Adhesion Molecule, Lynch syndrome, DNA-Binding Proteins, MutS Homolog 2 Protein, 030220 oncology & carcinogenesis, Female, Colorectal Neoplasms, Fanconi Anemia Complementation Group N Protein, MutL Protein Homolog 1, Adult, medicine.medical_specialty, Adenomatous Polyposis Coli Protein, Young Adult, 03 medical and health sciences, Germline mutation, Internal medicine, medicine, Humans, Genetic Predisposition to Disease, Germ-Line Mutation, Aged, business.industry, Genes, p16, Tumor Suppressor Proteins, Microsatellite instability, Cancer, medicine.disease, Colorectal Neoplasms, Hereditary Nonpolyposis, digestive system diseases, Checkpoint Kinase 2, 030104 developmental biology, Tumor Suppressor Protein p53, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5185111baac1b51ca8d1fa882da0b09eTest
https://doi.org/10.1200/jco.2016.71.0012Test

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