دورية أكاديمية
Effectiveness of diclofenac eyedrops in reducing inflammation and the incidence of cystoid macular edema after cataract surgery
| العنوان: | Effectiveness of diclofenac eyedrops in reducing inflammation and the incidence of cystoid macular edema after cataract surgery |
|---|---|
| المؤلفون: | L. Rossetti, N. Orzalesi, E. Bujtar, D. Castoldi, C. Torrazza |
| المساهمون: | L. Rossetti, E. Bujtar, D. Castoldi, C. Torrazza, N. Orzalesi |
| بيانات النشر: | American Society of Cataract and Refractive Surgery |
| سنة النشر: | 1996 |
| المجموعة: | The University of Milan: Archivio Istituzionale della Ricerca (AIR) |
| مصطلحات موضوعية: | blood-aqueous barrier, ketorolac tromethamine solution, intraocular-lens implantation, sodium ophthalmic solution, topical indomethacin, postoperative inflammation, extraction, breakdown, dexamethasone, flurbiprofen, Settore MED/30 - Malattie Apparato Visivo |
| الوصف: | PURPOSE: To evaluate the effectiveness of diclofenac eyedrops in reducing inflammation and the incidence of angiographic cystoid macular edema (CME) after cataract surgery and intraocular lens (IOL) implantation. SETTING: Eye Clinic, Institute of Biomedical Sciences, San Paolo Hospital, Milan, Italy. METHODS: Eighty-eight patients having cataract extraction were enrolled in a randomized clinical trial: 42 were given diclofenac eyedrops and 46, placebo. Postoperative inflammation in both groups was graded for 6 months using a dedicated system. RESULTS: Eight patients (9%) had evidence of angiographic CME approximately 1 month after surgery: seven of these were in the placebo group (P = .039). This difference was not significant 3 and 6 months postoperatively. The signs of ocular inflammation were greater in the eyes receiving placebo; the difference was particularly evident up to 1 week after surgery. There was no significant difference in visual acuity between the two groups at any follow-up point, but the contrast sensitivity of the eyes that received diclofenac improved significantly at 10.5 cycles per degree 1 month postoperatively. CONCLUSION: Diclofenac eyedrops effectively reduced ocular inflammation and the occurrence of angiographic CME after cataract surgery. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/9279674; info:eu-repo/semantics/altIdentifier/wos/WOS:A1996WB20600007; volume:22; issue:Suppl. 1; firstpage:794; lastpage:799; numberofpages:6; journal:JOURNAL OF CATARACT AND REFRACTIVE SURGERY; http://hdl.handle.net/2434/207260Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-0030325088 |
| DOI: | 10.1016/S0886-3350(96)80164-7 |
| الإتاحة: | https://doi.org/10.1016/S0886-3350Test(96)80164-7 http://hdl.handle.net/2434/207260Test |
| حقوق: | info:eu-repo/semantics/closedAccess |
| رقم الانضمام: | edsbas.90734F26 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/S0886-3350(96)80164-7 |
|---|