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1
المؤلفون: Shoji Asakura, Michiyuki Suzuki, Kazutomi Kusano, Takashi Ueno, Tomomi Ishida, Carsten T. Beuckmann, Jagadeesh Aluri, Takaaki Kameyama
المصدر: Drug Metabolism and Disposition. 49:31-38
مصطلحات موضوعية: Pharmacology, business.industry, Metabolite, Glucuronidation, Pharmaceutical Science, Urine, 030226 pharmacology & pharmacy, Orexin receptor, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Pharmacokinetics, chemistry, Oral administration, 030220 oncology & carcinogenesis, Medicine, business, Drug metabolism, ADME
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::310105c91488bc39459672158f368b02Test
https://doi.org/10.1124/dmd.120.000229Test -
2
المؤلفون: Friedbert Weiss, Alessandra Matzeu, Rémi Martin-Fardon, Tony M. Kerr
المصدر: Journal of Pharmacology and Experimental Therapeutics. 359:273-279
مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, Lateral hypothalamus, Pyridines, Drug-Seeking Behavior, Thalamus, Extinction, Psychological, Cocaine dependence, 03 medical and health sciences, 0302 clinical medicine, Cocaine, Orexin Receptors, Internal medicine, medicine, Animals, Urea, Drug Interactions, Naphthyridines, Rats, Wistar, Receptor, Pharmacology, Benzoxazoles, Orexins, Antagonist, Extinction (psychology), Isoquinolines, medicine.disease, Orexin receptor, Rats, Orexin, 030104 developmental biology, Endocrinology, Behavioral Pharmacology, Molecular Medicine, Psychology, 030217 neurology & neurosurgery, Paraventricular Hypothalamic Nucleus
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5be26fd0f80f31097ee12f2261515075Test
https://doi.org/10.1124/jpet.116.235945Test -
3
المؤلفون: Tommaso Miraval, Jasper Dingemanse, Gérard Hopfgartner, Kasra Shakeri-Nejad, Winfried Wagner-Redeker, Alexander Treiber, Matthias Hoch, Petra Hoever
المصدر: Drug Metabolism and Disposition. 41:1046-1059
مصطلحات موضوعية: Adult, Male, Receptors, Neuropeptide, Administration, Oral, Pharmaceutical Science, Pharmacology, Receptors, G-Protein-Coupled, Excretion, chemistry.chemical_compound, Orexin Receptors, Tandem Mass Spectrometry, Oral administration, Acetamides, medicine, Humans, Demethylation, Tetrahydroisoquinoline, Half-life, Metabolism, Isoquinolines, Orexin receptor, chemistry, Biochemistry, Almorexant, Chromatography, Liquid, Half-Life, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::350cc9c10a17e8666f21084f570fdea4Test
https://doi.org/10.1124/dmd.112.050120Test -
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المؤلفون: Sami Reijonen, Maria Jäntti, Johnny Näsman, Jaana Putula, Pauli M. Turunen, Christer Lindqvist, Jyrki P. Kukkonen
المصدر: Molecular Pharmacology. 83:621-632
مصطلحات موضوعية: Receptors, Neuropeptide, Cannabinoid receptor, Arachidonic Acids, CHO Cells, Immune receptor, Biology, Pharmacology, Glycerides, Receptors, G-Protein-Coupled, 03 medical and health sciences, 0302 clinical medicine, Receptor, Cannabinoid, CB1, Orexin Receptors, Cricetinae, Animals, Humans, Phosphorylation, Extracellular Signal-Regulated MAP Kinases, Receptor, Autocrine signalling, 030304 developmental biology, 0303 health sciences, Receptor, Muscarinic M1, Endocannabinoid system, Orexin receptor, Orexin, Cell biology, Autocrine Communication, Lipoprotein Lipase, Molecular Medicine, Signal transduction, 030217 neurology & neurosurgery, Endocannabinoids, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d08875e8b29c440ade307bf8db5fd8eTest
https://doi.org/10.1124/mol.112.080523Test -
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المؤلفون: Shang Cheng Huang, Ling Ling Hwang, Yu Wen E Dai, Yen Hsien Lee, Lih-Chu Chiou
المصدر: Journal of Pharmacology and Experimental Therapeutics. 334:522-529
مصطلحات موضوعية: Male, Receptors, Neuropeptide, medicine.medical_specialty, Patch-Clamp Techniques, Pyridines, Action Potentials, Blood Pressure, Receptors, G-Protein-Coupled, Orexin-A, Heart Rate, Orexin Receptors, Internal medicine, mental disorders, medicine, Animals, Premovement neuronal activity, Patch clamp, Neurons, Pharmacology, Medulla Oblongata, Orexins, Chemistry, Neuropeptides, digestive, oral, and skin physiology, Intracellular Signaling Peptides and Proteins, Rostral ventrolateral medulla, Isoquinolines, TCS-OX2-29, Immunohistochemistry, Orexin receptor, Rats, Orexin, Endocrinology, nervous system, Hypertension, Medulla oblongata, Molecular Medicine, Female, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dc3990a5c1ab5d4ac0d1cc274f75d02Test
https://doi.org/10.1124/jpet.110.167791Test -
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المؤلفون: Anne Marcuz, Pari Malherbe, Olivier Roche, Claudia Kratzeisen, Joseph G. Wettstein, Caterina Bissantz
المصدر: Molecular Pharmacology. 78:81-93
مصطلحات موضوعية: Pharmacology, Stereochemistry, Antagonist, Biology, Orexin receptor, Orexin, chemistry.chemical_compound, Transmembrane domain, chemistry, medicine, Molecular Medicine, Almorexant, Binding site, Receptor, medicine.drug, EMPA
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::195e5c9b026ae9d3fbafdc0bc260a541Test
https://doi.org/10.1124/mol.110.064584Test -
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المصدر: Molecular Pharmacology. 76:618-631
مصطلحات موضوعية: Receptors, Neuropeptide, medicine.medical_specialty, Pyrrolidines, Pharmacology, Receptors, G-Protein-Coupled, Orexin Receptors, Internal medicine, Acetamides, medicine, Animals, Humans, Receptor, Evoked Potentials, Neurons, Molecular Structure, Chemistry, Phenylurea Compounds, Dopaminergic, Antagonist, Isoquinolines, Orexin receptor, Rats, Orexin, Ventral tegmental area, Kinetics, Thiazoles, Endocrinology, medicine.anatomical_structure, Competitive antagonist, Molecular Medicine, Almorexant, Sleep, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afe058889cf26991657995fd0d4c9584Test
https://doi.org/10.1124/mol.109.055152Test -
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المؤلفون: Timothy W. Lovenberg, Sujin Yun, Jonathan Shelton, Brian Lord, Xiaohui Jiang, Ian Fraser, Nicholas I. Carruthers, Curt A. Dvorak, Steven W. Sutton, Xiaorong Li, Christine Dugovic, Leah Aluisio, Pascal Bonaventure
المصدر: Journal of Pharmacology and Experimental Therapeutics. 330:142-151
مصطلحات موضوعية: Male, Receptors, Neuropeptide, medicine.medical_specialty, Lateral hypothalamus, Rapid eye movement sleep, Receptors, G-Protein-Coupled, Rats, Sprague-Dawley, Orexin Receptors, Dopamine, Internal medicine, Acetamides, medicine, Animals, Pharmacology, Chemistry, Antagonist, Histaminergic, Isoquinolines, Orexin receptor, Rats, Orexin, Endocrinology, Molecular Medicine, Almorexant, Sleep, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::871ce5081cb8e9a7b9764ac17ca2c5ebTest
https://doi.org/10.1124/jpet.109.152009Test -
9
المصدر: Pharmacological Reviews. 58:46-57
مصطلحات موضوعية: Receptors, Neuropeptide, Hypothalamo-Hypophyseal System, medicine.medical_specialty, Pituitary-Adrenal System, Receptors, G-Protein-Coupled, Orexin Receptors, Internal medicine, mental disorders, medicine, Animals, Humans, Pharmacology, Orexins, Chemistry, Adrenal cortex, Neuropeptides, digestive, oral, and skin physiology, Intracellular Signaling Peptides and Proteins, Orexin receptor, Orexin, medicine.anatomical_structure, Endocrinology, Glucocorticoid secretion, nervous system, Catecholamine, Molecular Medicine, Adrenal medulla, psychological phenomena and processes, hormones, hormone substitutes, and hormone antagonists, Glucocorticoid, Hypothalamic–pituitary–adrenal axis, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d464269a73b84889eb1a344ce8a0103Test
https://doi.org/10.1124/pr.58.1.4Test -
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المؤلفون: René Bernard, Helen A. Baghdoyan, Ralph Lydic
المصدر: Journal of Pharmacology and Experimental Therapeutics. 317:163-171
مصطلحات موضوعية: Male, Receptors, Neuropeptide, medicine.medical_specialty, G protein, Microdialysis, Neurotransmission, Biology, Pertussis toxin, Receptors, G-Protein-Coupled, Rats, Sprague-Dawley, Orexin-A, GTP-Binding Proteins, Orexin Receptors, Internal medicine, mental disorders, medicine, Animals, Protein Isoforms, Receptor, Chromatography, High Pressure Liquid, Pharmacology, Orexins, Dose-Response Relationship, Drug, Neuropeptides, fungi, Intracellular Signaling Peptides and Proteins, Acetylcholine, Orexin receptor, Rats, nervous system diseases, Orexin, Endocrinology, Pertussis Toxin, nervous system, Molecular Medicine, psychological phenomena and processes, Brain Stem, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd02d331e7ee51e73c6858eef6be23b1Test
https://doi.org/10.1124/jpet.105.097071Test