المؤلفون: Goncalves, Bronner P., Pett, Helmi, Tiono, Alfred B., Murry, Daryl, Sirima, Sodiomon B., Niemi, Mikko, Bousema, Teun, Drakeley, Chris, ter Heine, Rob

المساهمون: Clinicum, University of Helsinki, Department of Clinical Pharmacology, Medicum, HUSLAB

مصطلحات موضوعية: pharmacokinetics, primaquine, Plasmodium falciparum, CYP2D6, PLASMODIUM-VIVAX MALARIA, SINGLE-DOSE PRIMAQUINE, NEW-GUINEAN CHILDREN, ARTEMETHER-LUMEFANTRINE, DIHYDROARTEMISININ-PIPERAQUINE, UNCOMPLICATED MALARIA, FALCIPARUM-MALARIA, CONTROLLED-TRIAL, RADICAL CURE, DOUBLE-BLIND, 3111 Biomedicine, 3123 Gynaecology and paediatrics

وصف الملف: application/pdf

العلاقة: This study was supported by the Bill and Melinda Gates Foundation (AFIRM OPP1034789). T.B. is supported by a fellowship from the European Research Council (ERC-2014-StG 639776).; Goncalves , B P , Pett , H , Tiono , A B , Murry , D , Sirima , S B , Niemi , M , Bousema , T , Drakeley , C & ter Heine , R 2017 , ' Age, Weight, and CYP2D6 Genotype Are Major Determinants of Primaquine Pharmacokinetics in African Children ' , Antimicrobial Agents and Chemotherapy , vol. 61 , no. 5 , 02590 . https://doi.org/10.1128/AAC.02590-16Test; 85018178364; 18a8db4e-9920-47fa-a2e8-1c5ada27aea9; http://hdl.handle.net/10138/203372Test; 000403532100074

الإتاحة: http://hdl.handle.net/10138/203372Test

المؤلفون: Richard M. Hoglund, Martha M. Lemnge, Kimberley K Scarsi, Saye Khoo, Stephen Walimbwa, Sunil Parikh, Mohammed Lamorde, Lesley Workman, Karen I. Barnes, Jose Francis, Ifeyinwa Chijioke-Nwauche, Paolo Denti, Colin J. Sutherland, Francesca T. Aweeka, Nyagonde Nyagonde, Joel Tarning, Concepta Merry, Ib C. Bygbjerg, Lasse S Vestergaard, Tamara Kredo, Pauline Byakika-Kibwika

المصدر: Antimicrobial Agents and Chemotherapy
Francis, J, Barnes, K I, Workman, L, Kredo, T, Vestergaard, L S, Hoglund, R M, Byakika-Kibwika, P, Lamorde, M, Walimbwa, S I, Chijioke-Nwauche, I, Sutherland, C J, Merry, C, Scarsi, K K, Nyagonde, N, Lemnge, M M, Khoo, S H, Bygbjerg, I C, Parikh, S, Aweeka, F T, Tarning, J & Denti, P 2020, ' An Individual Participant Data Population Pharmacokinetic Meta-Analysis of Drug-drug Interactions between Lumefantrine and Commonly-used Antiretroviral Treatment ', Antimicrobial Agents and Chemotherapy, vol. 64, no. 5, e02394 . https://doi.org/10.1128/AAC.02394-19Test

مصطلحات موضوعية: Male, drug-drug interactions, uncomplicated malaria, HIV Infections, Lopinavir, chemistry.chemical_compound, 0302 clinical medicine, population pharmacokinetics, Antiretroviral Therapy, Highly Active, Medicine, Pharmacology (medical), Drug Interactions, 030212 general & internal medicine, 0303 health sciences, education.field_of_study, human immunodeficiency virus, virus diseases, Middle Aged, Infectious Diseases, Dolutegravir, Female, Monte Carlo Method, medicine.drug, Adult, medicine.medical_specialty, Efavirenz, Nevirapine, Adolescent, Anti-HIV Agents, Population, lumefantrine, Clinical Therapeutics, Lumefantrine, 03 medical and health sciences, Antimalarials, Young Adult, Pharmacokinetics, Internal medicine, parasitic diseases, Humans, Computer Simulation, education, Aged, Pharmacology, Ritonavir, 030306 microbiology, business.industry, Artemether, Lumefantrine Drug Combination, Body Weight, medicine.disease, Malaria, Regimen, chemistry, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0399802a363c8c72e12d38fee364a18aTest
https://researchonline.lshtm.ac.uk/id/eprint/4656336/8/Francis-etal-2020_An_Individual_Participant_Data_Population.pdfTest

المؤلفون: Veiga, M. I., Ferreira, P. E., Malmberg, M., Jornhagen, L., Bjorkman, A., Nosten, F., Gil, J. P.

مصطلحات موضوعية: Multidrug-resistance gene, Artemether-Lumefantrine, Dihydroartemisinin-Piperaquine, Malaria parasites, Copy number, Artemisinin resistance, Mefloquine resistance, Uncomplicated malaria, Northwestern border, Selection

العلاقة: info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBPD%2F76614%2F2011/PT; http://hdl.handle.net/10400.1/11468Test

الإتاحة: https://doi.org/10.1128/AAC.06350-11Test
http://hdl.handle.net/10400.1/11468Test

المؤلفون: Anne Fox, Benjamin Abuaku, Sena A. Matrevi, Andrew G. Letizia, Philip Opoku-Agyeman, Neils B. Quashie, Kwadwo A. Koram, Nancy O Duah-Quashie, Selassie Bruku

مصطلحات موضوعية: Nonsynonymous substitution, Male, Combination therapy, Genotype, 030231 tropical medicine, Plasmodium falciparum, Drug Resistance, Protozoan Proteins, Biology, Ghana, Polymorphism, Single Nucleotide, Uncomplicated malaria, Epidemiology and Surveillance, Efficacy, 03 medical and health sciences, Antimalarials, 0302 clinical medicine, parasitic diseases, medicine, Humans, Pharmacology (medical), Artemisinin, Malaria, Falciparum, Child, Pharmacology, 0303 health sciences, 030306 microbiology, medicine.disease, biology.organism_classification, Virology, Artemisinins, Infectious Diseases, Chemoprophylaxis, Female, Malaria, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a79ab6a5fc4eee13dca0a3555663c4f8Test
https://europepmc.org/articles/PMC6811449Test/

المؤلفون: Pedro Eduardo Ferreira, José Pedro Gil, Anders Björkman, Louise Jörnhagen, François Nosten, Maja Malmberg, Maria Isabel Veiga

المساهمون: Universidade do Minho

المصدر: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

مصطلحات موضوعية: Combination therapy, medicine.medical_treatment, CNV, Plasmodium falciparum, Gene Dosage, Protozoan Proteins, Uncomplicated malaria, Dihydroartemisinin, Pharmacology, Gene dosage, Antimalarials, 03 medical and health sciences, pfmdr1, Mechanisms of Resistance, Chloroquine, Piperaquine, parasitic diseases, medicine, Pharmacology (medical), Northwestern border, Artemisinin, Selection, 030304 developmental biology, 0303 health sciences, Science & Technology, biology, Malaria parasites, Copy number, 030306 microbiology, Multidrug-resistance gene, biology.organism_classification, Mefloquine resistance, 3. Good health, Multiple drug resistance, Infectious Diseases, Artemisinin resistance, Artemether-Lumefantrine, Dihydroartemisinin-Piperaquine, Quinolines, ATP-Binding Cassette Transporters, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::627ce5b1d32ba9dbe8476e26238edac3Test
https://hdl.handle.net/10400.1/11468Test