Haselmann, K, Nielsen, P F & Zubarev, R A 2005, ' Characterization of an N-acylated glucagon-like peptide-1 derivative by electron capture dissociation ', Journal of the American Society for Mass Spectrometry, vol. 16, no. 4, pp. 548-552 . https://doi.org/10.1016/j.jasms.2005.01.009Test
بيانات النشر:
American Society for Mass Spectrometry. Published by Elsevier B.V.
An N-acylated glucagon-like peptide 1 derivative was characterized by Fourier transform ion cyclotron resonance mass spectrometry. Both electron capture dissociation (ECD) and sustained off-resonance irradiation collisionally activated dissociation (SORI-CAD) were employed. While ECD revealed full sequence coverage, site of modification, branching point, structure of the palmitoylated modification, SORI-CAD produced less complete and more ambiguous information attributable to facile losses of the fatty acid group from both parent and fragments. Thus, ECD showed a superior characterization performance over SORI-CAD in analysis of N-acylated polypeptides.
