نتائج البحث

1

Brain functions and cognition on transient insulin deprivation in type 1 diabetes

المؤلفون: John D. Port, Tiffany Cortes, Gregory N. Ruegsegger, Ana L. Creo, Andrea R.S. Huebner, Yogish C. Kudva, Aida N. Lteif, Katherine A. Klaus, Surendra Dasari, K. Sreekumaran Nair, Hang Joon Jo, Ronald C. Petersen, Jan Mendelt Tillema

المصدر: JCI Insight, Vol 6, Iss 5 (2021)
JCI Insight

مصطلحات موضوعية: Adult, Blood Glucose, Male, 0301 basic medicine, medicine.medical_specialty, medicine.medical_treatment, Pilot Projects, Phosphocreatine, Young Adult, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, Memory, Diabetes mellitus, Internal medicine, Fractional anisotropy, medicine, Insulin, Humans, Dementia, Cognitive Dysfunction, Sensory cortex, Translational Science, Biomedical, Type 1 diabetes, business.industry, Diabetes, Cognition, Somatosensory Cortex, General Medicine, medicine.disease, Diabetes Mellitus, Type 1, 030104 developmental biology, medicine.anatomical_structure, chemistry, 030220 oncology & carcinogenesis, Medicine, Female, Clinical Medicine, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df35e605fd35bca18e9e9717df343f45Test
https://doaj.org/article/89e91ea96c224a14803019bb961e2cc3Test

2

CD4+CD25+CD127hi cell frequency predicts disease progression in type 1 diabetes

المؤلفون: Mark Harris, Ranjeny Thomas, Martin J. Hessner, Rhonda Geoffrey, Anne-Sophie Bergot, Breanna Lam, Kerry Buchanan, Elisavet Serti, Rosita Moya, Alessandra Mandelli, Irene Gotuzzo, Manuela Battaglia, Joanna D. Davies, Aditi Narsale, Benedetta Pessina, Gian Maria Giamporcaro, TingTing Lu

المصدر: JCI Insight, Vol 6, Iss 2 (2021)
JCI Insight

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Male, 0301 basic medicine, Oncology, Autoimmune diseases, medicine.medical_treatment, Cell, Autoimmunity, medicine.disease_cause, 0302 clinical medicine, T-Lymphocyte Subsets, IL-2 receptor, Child, education.field_of_study, Diabetes, General Medicine, medicine.anatomical_structure, Child, Preschool, 030220 oncology & carcinogenesis, Disease Progression, Medicine, Female, Immunotherapy, Research Article, medicine.drug, Adult, medicine.medical_specialty, Adolescent, Population, Immunology, T cells, Alefacept, Interleukin-7 Receptor alpha Subunit, Young Adult, 03 medical and health sciences, Diabetes mellitus, Internal medicine, medicine, Humans, education, Proportional Hazards Models, Type 1 diabetes, business.industry, Interleukin-2 Receptor alpha Subunit, Infant, medicine.disease, Diabetes Mellitus, Type 1, 030104 developmental biology, Multivariate Analysis, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b18ca9272dda4aa45bece327b8ae55f8Test
https://doaj.org/article/20ba8c4ce6b4454ea7c69dca229e3557Test

3

The effect of low-dose IL-2 and Treg adoptive cell therapy in patients with type 1 diabetes

المصدر: JCI Insight

مصطلحات موضوعية: Adult, Male, Time Factors, Combination therapy, Cell Survival, medicine.medical_treatment, T cell, T cells, Autoimmunity, chemical and pharmacologic phenomena, CD8-Positive T-Lymphocytes, medicine.disease_cause, Immunotherapy, Adoptive, T-Lymphocytes, Regulatory, Cell therapy, Young Adult, Immune system, medicine, Humans, Hypoglycemic Agents, Insulin, Cytotoxic T cell, Clinical Trials, Lymphocyte Count, Glycated Hemoglobin, C-Peptide, business.industry, Diabetes, General Medicine, Immunotherapy, Combined Modality Therapy, Recombinant Proteins, Diabetes Mellitus, Type 1, medicine.anatomical_structure, Immunology, Interleukin-2, Natural Killer T-Cells, Female, Clinical Medicine, Transcriptome, business, CD8

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::983c76b05789c8ccfe05b979c8255f10Test
https://doi.org/10.1172/jci.insight.147474Test

4

Immunomodulatory activity of humanized anti–IL-7R monoclonal antibody RN168 in subjects with type 1 diabetes

المؤلفون: Kevan C. Herold, Gilbert Y. Wong, Tenshang Joh, Shobha Potluri, Peter A. Gottlieb, Bruce W. Bode, Matteo Levisetti, Janet B. McGill, Megan Shannon, Bishu J Ganguly, Jing W. Hughes, Samantha L. Bucktrout, Desmond A. Schatz, Stephen E. Gitelman, Jeremy Pettus, Xiao Wang, Pamela D. Garzone, Chandrasekhar Udata

المصدر: JCI Insight. 4

مصطلحات موضوعية: Adult, CD4-Positive T-Lymphocytes, Male, 0301 basic medicine, Cell Survival, medicine.drug_class, medicine.medical_treatment, T cell, Dose-Response Relationship, Immunologic, CD8-Positive T-Lymphocytes, Antibodies, Monoclonal, Humanized, Monoclonal antibody, Interleukin-7 Receptor alpha Subunit, 03 medical and health sciences, 0302 clinical medicine, Immune system, medicine, Humans, Type 1 diabetes, Dose-Response Relationship, Drug, biology, business.industry, Interleukin-7, General Medicine, Middle Aged, medicine.disease, Diabetes Mellitus, Type 1, Treatment Outcome, 030104 developmental biology, Cytokine, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Immunology, Monoclonal, biology.protein, Female, Antibody, business, Immunologic Memory, CD8, Signal Transduction, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::406708a6949f1f766cbebb2d99dd6f96Test
https://doi.org/10.1172/jci.insight.126054Test

5

Galectin-1–driven T cell exclusion in the tumor endothelium promotes immunotherapy resistance

المؤلفون: A. Dimitrios Colevas, Joshua Bloomstein, Rie von Eyben, Clint T. Allen, Vangipuram S. Rangan, Todd A. Aguilera, Albert C. Koong, Quynh-Thu Le, Dadi Jiang, Hongbin Cao, Christina S. Kong, Shirley Kwok, Amato J. Giaccia, Alan J. Korman, Sonya Agarwal, Rachel Liang, Dhanya Nambiar, Zemin Wang, Ravindra Uppaluri

المصدر: J Clin Invest

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Firearms, Galectin 1, Galectins, medicine.medical_treatment, T cell, T-Lymphocytes, Programmed Cell Death 1 Receptor, B7-H1 Antigen, 03 medical and health sciences, Mice, 0302 clinical medicine, Immune system, Downregulation and upregulation, Immune Tolerance, Medicine, Animals, Humans, Endothelium, Aged, Aged, 80 and over, business.industry, General Medicine, Immunotherapy, Middle Aged, Blockade, Mice, Inbred C57BL, Radiation therapy, carbohydrates (lipids), STAT1 Transcription Factor, 030104 developmental biology, medicine.anatomical_structure, Head and Neck Neoplasms, 030220 oncology & carcinogenesis, Galectin-1, Commentary, T cell migration, Cancer research, Female, business, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10ae2195bd4106f7d6202d49886da83dTest
https://europepmc.org/articles/PMC6877340Test/

6

A composite immune signature parallels disease progression across T1D subjects

المؤلفون: Martin J. Hessner, Jared M. Odegard, Eddie A. James, Alberto Pugliese, Megan K. Levings, S. Alice Long, Raphael Gottardo, Elizabeth Whalen, Dror Berel, William Chad Young, Anne M. Pesenacker, Eitan M. Akirav, Peter S. Linsley, Matthew J. Dufort, Samuel O. Skinner, Cate Speake, Gerald T. Nepom, Frans K. Gorus

المساهمون: Diabetes Clinic, Vriendenkring VUB, Pathology/molecular and cellular medicine, Diabetes Pathology & Therapy

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b237eb399f4c696b73c3089204ac4f61Test
https://hdl.handle.net/20.500.14017/ad1c22ad-24e5-4641-9e96-e70d7e73fa70Test

7

PD-1 blockade improves Kupffer cell bacterial clearance in acute liver injury

المؤلفون: Matthew K. Siggins, Wafa Khamri, Thomas O’Connor, Evangelos Triantafyllou, Mark Thursz, Marie-Anne Mawhin, Mark J. W. McPhail, Hannah C. Husbyn, Kevin J. Woollard, Sujit Mukherjee, Marina Botto, Cathrin Gudd, Robert D. Goldin, Christine Bernsmeier, Charalambos G. Antoniades, Lucia A. Possamai, Francesca M. Trovato, Julia Wendon, Hiromi Kudo

المساهمون: Medical Research Council (MRC)

المصدر: The Journal of Clinical Investigation

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Kupffer Cells, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Immunology, Flow cytometry, Sepsis, Mice, 03 medical and health sciences, 0302 clinical medicine, Immune system, medicine, Animals, Humans, Immune Checkpoint Inhibitors, 11 Medical and Health Sciences, Acetaminophen, Mice, Knockout, Innate immunity, Liver injury, Innate immune system, Bacteria, Hepatology, medicine.diagnostic_test, business.industry, Macrophages, Monocyte, Kupffer cell, Bacterial Infections, General Medicine, Immunotherapy, Middle Aged, medicine.disease, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Female, Chemical and Drug Induced Liver Injury, business, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e57ff30014337155b03c74b6c2ac765aTest
https://doi.org/10.1172/jci140196Test

8

CD19 CAR T cell product and disease attributes predict leukemia remission durability

المؤلفون: Hannah Brakke, Olivia Finney, Roxana Hicks, Daniel Li, Stephanie Rawlings-Rhea, Rebecca Gardner, Ben Futrell, Marisa Lopez, Michael C. Jensen, Rimas J. Orentas, Danielle Doolittle

المصدر: J Clin Invest

مصطلحات موضوعية: Male, 0301 basic medicine, Oncology, Adoptive cell transfer, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Kaplan-Meier Estimate, Hematopoietic stem cell transplantation, CD8-Positive T-Lymphocytes, Lymphocyte Activation, Immunotherapy, Adoptive, 0302 clinical medicine, Recurrence, Cytotoxic T cell, Child, Hepatitis A Virus Cellular Receptor 2, Leukemia, Receptors, Chimeric Antigen, Gene Expression Regulation, Leukemic, Remission Induction, Hematopoietic Stem Cell Transplantation, General Medicine, Aplasia, Lymphocyte Activation Gene 3 Protein, Phenotype, medicine.anatomical_structure, Child, Preschool, 030220 oncology & carcinogenesis, Female, Adult, medicine.medical_specialty, Adolescent, Antigens, CD19, Disease-Free Survival, Immunophenotyping, Young Adult, 03 medical and health sciences, Antigen, Antigens, CD, Internal medicine, medicine, Humans, B cell, Cell Proliferation, Tumor Necrosis Factor-alpha, business.industry, Infant, medicine.disease, Chimeric antigen receptor, 030104 developmental biology, Commentary, K562 Cells, business, CD8

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a113c5e07f7fbde58d76de414a97babfTest
https://doi.org/10.1172/jci125423Test

9

Profiling of patients with glioma reveals the dominant immunosuppressive axis is refractory to immune function restoration

المصدر: JCI Insight
JCI Insight, Vol 5, Iss 17 (2020)

مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Cancer immunotherapy, Brain cancer, Mice, 0302 clinical medicine, 5'-Nucleotidase, Immune Checkpoint Inhibitors, Cells, Cultured, Brain Neoplasms, Apyrase, Glioma, General Medicine, Middle Aged, Isocitrate Dehydrogenase, Oncology, 030220 oncology & carcinogenesis, Medicine, Female, Immunosuppressive Agents, Research Article, medicine.drug, Adult, IDH1, Receptor, Adenosine A2A, Immunology, 03 medical and health sciences, Immune system, Downregulation and upregulation, Antigens, CD, Cell Line, Tumor, medicine, Animals, Humans, Aged, business.industry, Therapeutic effect, medicine.disease, Adenosine, Adenosine receptor, Mice, Inbred C57BL, 030104 developmental biology, Cancer research, Neoplasm Grading, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1b7362d1d0c19278cd2192b48b6dbf5Test
https://doi.org/10.1172/jci.insight.134386Test

10

Ovarian granulosa cell tumor characterization identifies FOXL2 as an immunotherapeutic target

المؤلفون: Mark A. Morgan, Robert A. Burger, Mireia Uribe-Herranz, Stefano Pierini, Erin George, Fiona Simpkins, Janos L. Tanyi, Andrea Facciabene, Ronny Drapkin

المصدر: JCI Insight, Vol 5, Iss 16 (2020)
JCI Insight

مصطلحات موضوعية: 0301 basic medicine, Adult, Forkhead Box Protein L2, medicine.medical_treatment, Population, Programmed Cell Death 1 Receptor, Immunology, Immune Targeting, Cancer immunotherapy, Mice, Inbred Strains, Cancer Vaccines, 03 medical and health sciences, Epitopes, 0302 clinical medicine, Immune system, Lymphocytes, Tumor-Infiltrating, Pregnancy, Cell Line, Tumor, Immune Tolerance, Tumor Microenvironment, Vaccines, DNA, Medicine, Animals, Humans, education, Immune Checkpoint Inhibitors, Granulosa Cell Tumor, education.field_of_study, business.industry, Tumor-infiltrating lymphocytes, General Medicine, Middle Aged, Xenograft Model Antitumor Assays, 030104 developmental biology, Forkhead box L2, Immunization, Oncology, Tumor progression, 030220 oncology & carcinogenesis, Cancer research, Female, business, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::255c99bb3ed436759c3786738dc4cef4Test
https://doaj.org/article/3ee8feab99b74b3781439e0dd4109565Test

تنقيح النتائج