المؤلفون: Peng Li, Leqing Zhu, Liehua Deng, Zhizhong Li, Hua Zhang, Yueqi Song, Xichun Xia, Jianlei Hao, Xiao Wang, Chengbin Guo, Zhinan Yin, Guangchao Cao, Yixia Tian, Wei Zhou, Yunfei Gao, Jingxiang Zhong, Guodong Sun

المصدر: J Clin Invest

مصطلحات موضوعية: Adult, Keratinocytes, Male, 0301 basic medicine, Chemokine, Glutamine, Cellular differentiation, medicine.disease_cause, Autoimmunity, Mice, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Glutaminase, T-Lymphocyte Subsets, Psoriasis, medicine, Animals, Humans, RNA, Messenger, Histone H3 acetylation, Aged, Mice, Knockout, Glutaminolysis, biology, Chemistry, Interleukin-17, Cell Differentiation, General Medicine, Middle Aged, medicine.disease, Mice, Inbred C57BL, Disease Models, Animal, MALT1, 030104 developmental biology, Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein, Case-Control Studies, 030220 oncology & carcinogenesis, biology.protein, Cancer research, Th17 Cells, Female, IL17A, Metabolic Networks and Pathways, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1f6d904955d64d82e287033ac565778Test
https://doi.org/10.1172/jci129269Test

المؤلفون: Elisavet Serti, Todd M. Brusko, Keshav Motwani, Fariba Barahmand-pour-Whitman, Karen Cerosaletti, Colin O’Rourke, Alex Hu, Peter S. Linsley, Janice Chen, Gerald T. Nepom, Elisa Balmas, Carla J. Greenbaum, Cate Speake, William W. Kwok, Hannah A. DeBerg, Kaitlin J. Flynn, Mario G. Rosasco, Howard R. Seay, Vivian H. Gersuk

المصدر: JCI Insight

مصطلحات موضوعية: Adult, Male, Adolescent, Population, Receptors, Antigen, T-Cell, chemical and pharmacologic phenomena, Autoimmunity, Biology, medicine.disease_cause, Immunoglobulin alpha-Chains, Germline, Epitope, Young Adult, Antigen, medicine, Humans, CD154, education, education.field_of_study, T-cell receptor, RNA, hemic and immune systems, General Medicine, Cell biology, Diabetes Mellitus, Type 1, Germ Cells, Resource and Technical Advance, Female, T cell receptor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16ac74b43405ccf18113a29d94d5a638Test
http://europepmc.org/articles/PMC8663791Test

المؤلفون: Christian Drosten, Olga Staudacher, Christine Goffinet, Dirk Schnabel, Marcus A. Mall, Uwe Kölsch, Horst von Bernuth, Timothy W. Meyer, Bengisu Akbil, Christian Meisel, Tilmann Kallinich, Victor M. Corman, Erwin Lankes, Nadine Unterwalder

المصدر: J Clin Invest

مصطلحات موضوعية: Adult, Male, Adolescent, Population, Alpha interferon, In Vitro Techniques, Virus Replication, Severity of Illness Index, Young Adult, medicine, Humans, STAT1, Polyendocrinopathies, Autoimmune, education, Autoantibodies, education.field_of_study, biology, SARS-CoV-2, business.industry, Concise Communication, Autoantibody, COVID-19, Interferon-alpha, General Medicine, medicine.disease, Antibodies, Neutralizing, Penetrance, Titer, Autoimmune polyendocrine syndrome type 1, Interferon Type I, Immunology, biology.protein, Female, business, Interferon type I, Transcription Factors, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e524e8a06eab2ba92b83c7a864e7f2dTest
https://doi.org/10.1172/jci150867Test

المؤلفون: John R. Jimah, Manuel Duarte, Nick Huang, Tiffany Caza, Miguel Beckford, Katalin Banki, Eric M. Poeschla, Hind J. Fadel, Ryan Kelly, Aparna Godavarthy, David Fernandez, Joshua Lewis, Andras Perl

مصطلحات موضوعية: 0301 basic medicine, Adult, DNA (Cytosine-5-)-Methyltransferase 1, Adolescent, T cell, T-Lymphocytes, Receptors, Antigen, T-Cell, DNA methyltransferase, Epigenesis, Genetic, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Transcription (biology), medicine, Humans, Lupus Erythematosus, Systemic, Epigenetics, Enhancer, Mechanistic target of rapamycin, PI3K/AKT/mTOR pathway, Alleles, Adaptor Proteins, Signal Transducing, Aged, biology, Nuclear Respiratory Factor 1, TOR Serine-Threonine Kinases, Endogenous Retroviruses, Terminal Repeat Sequences, General Medicine, DNA Methylation, Middle Aged, HCT116 Cells, Molecular biology, Long terminal repeat, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, biology.protein, Female, Research Article, HeLa Cells, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd0948814ebdf568c5f45b11a8c916dbTest
https://europepmc.org/articles/PMC7030820Test/

المؤلفون: Baroj Abdulkarim, Miriam Cnop, Marina Boscolo, Ana F Oliveira, Satyan Chintawar, Céline Demarez, Sanna Toivonen, Mohammad Tariq, Mariana Igoillo-Esteve, Miguel Lopes, Piero Marchetti, Decio L. Eizirik, Massimo Pandolfo, Myriam Rai, Amélie Hu, Federica Fantuzzi, Jean-Christophe Jonas, Ying Cai, Cristina Cosentino, Lorella Marselli, Nathalie Pachera

المساهمون: UCL - SSS/IREC - Institut de recherche expérimentale et clinique, UCL - SSS/IREC/EDIN - Pôle d'endocrinologie, diabète et nutrition

المصدر: JCI Insight, Vol. 5, no. 2, p. e134221 (2020)
JCI Insight
JCI insight

مصطلحات موضوعية: Male, 0301 basic medicine, Mitochondrion, Mice, Endocrinology, 0302 clinical medicine, Glucagon-Like Peptide 1, Cerebellum, Ganglia, Spinal, Insulin-Secreting Cells, Iron-Binding Proteins, Insulin, Glucose homeostasis, Gene Knock-In Techniques, Mice, Knockout, biology, Diabetes, Neurodegeneration, Brain, General Medicine, Middle Aged, Sciences bio-médicales et agricoles, Mitochondria, 3. Good health, 030220 oncology & carcinogenesis, Female, medicine.symptom, Research Article, medicine.drug, Adult, medicine.medical_specialty, congenital, hereditary, and neonatal diseases and abnormalities, Ataxia, Adolescent, Iron, Incretin, Neuroscience, Neuroprotection, Young Adult, 03 medical and health sciences, Internal medicine, medicine, Animals, Humans, Aged, business.industry, medicine.disease, Disease Models, Animal, Oxidative Stress, 030104 developmental biology, Gene Expression Regulation, Friedreich Ataxia, Frataxin, biology.protein, Exenatide, Reactive Oxygen Species, Trinucleotide Repeat Expansion, business

وصف الملف: 2 full-text file(s): application/pdf; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22b200b55a913111fdc37f52ecd11c1aTest
https://hdl.handle.net/2078Test.1/225377

المؤلفون: Marco Klinger, Stefania Vetrano, Biagio Di Lorenzo, Michele Carvello, Anna Villa, Marita Bosticardo, Silvio Danese, Massimo Roncalli, Francesco Dieli, Antonino Spinelli, Elena Bruni, Ileana Bortolomai, Alessandra Roberto, Matteo Sacchi, Bruno Silva-Santos, Immo Prinz, Federico Colombo, Ferdinando Oriolo, Elena Lo Presti, Paola Spaggiari, Giovanni Cugini, Emanuela Marcenaro, Giovanni Colombo, Joanna Mikulak, Sarina Ravens, Serena Meraviglia, Domenico Mavilio, Silvia Della Bella

المساهمون: Mikulak, Joanna, Oriolo, Ferdinando, Bruni, Elena, Roberto, Alessandra, Colombo, Federico S, Villa, Anna, Bosticardo, Marita, Bortolomai, Ileana, Lo Presti, Elena, Meraviglia, Serena, Dieli, Francesco, Vetrano, Stefania, Danese, Silvio, Della Bella, Silvia, Carvello, Michele M, Sacchi, Matteo, Cugini, Giovanni, Colombo, Giovanni, Klinger, Marco, Spaggiari, Paola, Roncalli, Massimo, Prinz, Immo, Ravens, Sarina, di Lorenzo, Biagio, Marcenaro, Emanuela, Silva-Santos, Bruno, Spinelli, Antonino, Mavilio, Domenico

مصطلحات موضوعية: 0301 basic medicine, Male, Colorectal cancer, Immunotherapy, Adoptive, Mice, 0302 clinical medicine, Sex Hormone-Binding Globulin, Cytotoxic T cell, Antigens, Ly, Intestinal Mucosa, Intraepithelial Lymphocytes, Innate immunity, Aged, 80 and over, Gastroenterology, Age Factors, Receptors, Antigen, T-Cell, gamma-delta, General Medicine, Middle Aged, Phenotype, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Disease Progression, Female, Colorectal Neoplasms, Research Article, Adult, Colon, T cell, Immunology, T cells, Biology, digestive system, 03 medical and health sciences, Young Adult, Ileum, medicine, Animals, Humans, Aged, Neoplasm Staging, Tumor microenvironment, Innate immune system, Natural Cytotoxicity Triggering Receptor 1, medicine.disease, 030104 developmental biology, Cancer research, Intraepithelial lymphocyte, Homing (hematopoietic), T-Lymphocytes, Cytotoxic

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b1e3fbd8fd94fdf6ed061ea76ae26ebTest
https://europepmc.org/articles/PMC6975269Test/

المؤلفون: Maran L. Sprouse, Thomas Lee, Marissa A. Scavuzzo, Samuel Blum, Ivan Shevchenko, Matthew L. Bettini, Maria Bettini, George Makedonas, Malgorzata Borowiak

المصدر: JCI Insight. 3

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Tcr signaling, Primary Cell Culture, Receptors, Antigen, T-Cell, Autoimmunity, Mice, Transgenic, chemical and pharmacologic phenomena, Mice, SCID, Biology, CD5 Antigens, medicine.disease_cause, Immunotherapy, Adoptive, T-Lymphocytes, Regulatory, Islets of Langerhans, Mice, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Mice, Inbred NOD, medicine, Animals, Humans, Tissue specific, Cells, Cultured, Self reactivity, Lineage commitment, T-cell receptor, hemic and immune systems, General Medicine, Healthy Volunteers, Disease Models, Animal, Diabetes Mellitus, Type 1, 030104 developmental biology, Immunology, Female, CD5, T-Box Domain Proteins, Function (biology), Research Article, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bceb91c646ef4031118f096cb3f72935Test
https://doi.org/10.1172/jci.insight.97322Test

المؤلفون: Jonathan G. Schoenecker, Nicholas A. Mignemi, Justin M M Cates, William T. Obremskey, Chenguang Zhao, Toshitaka Yoshii, Herbert S. Schwartz, Gourab Bhattacharjee, Jesse E. Bible, Craig L. Duvall, Matthew J. Flick, Jeffry S. Nyman, Jay L. Degen, Joey V. Barnett, Atsushi Okawa, Masato Yuasa

المصدر: Journal of Clinical Investigation. 125:1827-1838

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Male, medicine.medical_treatment, Fracture (mineralogy), Antitubercular Agents, CD38, Lymphocyte Activation, South Africa, Clinical investigation, Interferon gamma, Aged, 80 and over, Membrane Glycoproteins, biology, medicine.diagnostic_test, Latent tuberculosis, General Medicine, Middle Aged, Flow Cytometry, 3. Good health, Female, Drug Monitoring, medicine.symptom, Corrigendum, medicine.drug, Adult, medicine.medical_specialty, Georgia, Tuberculosis, Adolescent, Sensitivity and Specificity, Asymptomatic, Sputum culture, Diagnosis, Differential, Mycobacterium tuberculosis, Interferon-gamma, Young Adult, Latent Tuberculosis, Fibrinolysis, medicine, Humans, Tuberculosis, Pulmonary, Aged, business.industry, Sputum, HLA-DR Antigens, bacterial infections and mycoses, biology.organism_classification, medicine.disease, ADP-ribosyl Cyclase 1, Surgery, Ki-67 Antigen, Asymptomatic Diseases, Immunology, Heterotopic ossification, Clinical Medicine, business, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52074528e023aafdb3fb63436dd019c0Test
https://doi.org/10.1172/jci77990Test

المؤلفون: David M. Koelle, Jürgen Haas, Georges M. G. M. Verjans, Christopher L. McClurkan, Joseph J. Bruckner, Anna Wald, Lichun Dong, Tori N. Yamamoto, Susanne M. Bailer, Joshua O. Marshak, Lichen Jing, Tiana M. Chong, Greg C. Dann, Kerry J. Laing

المساهمون: Publica, Virology

المصدر: Jing, L, Haas, J, Chong, T M, Bruckner, J J, Dann, G C, Dong, L, Marshak, J O, McClurkan, C L, Yamamoto, T N, Bailer, S M, Laing, K J, Wald, A, Verjans, G M G M & Koelle, D M 2012, ' Cross-presentation and genome-wide screening reveal candidate T cells antigens for a herpes simplex virus type 1 vaccine ', Journal of Clinical Investigation, vol. 122, no. 2, pp. 654-673 . https://doi.org/10.1172/JCI60556Test
Journal of Clinical Investigation, 122(2), 654-673. The American Society for Clinical Investigation

مصطلحات موضوعية: Adult, CD4-Positive T-Lymphocytes, Cytotoxicity, Immunologic, Male, viruses, T cell, Herpesvirus 1, Human, Human leukocyte antigen, Streptamer, CD8-Positive T-Lymphocytes, Biology, medicine.disease_cause, Genome, Interferon-gamma, Tumor Necrosis Factor Receptor Superfamily, Member 9, Young Adult, Cross-Priming, SDG 3 - Good Health and Well-being, Antigen, HLA Antigens, Clinical investigation, medicine, Humans, Antigens, Viral, Pan-T antigens, Cells, Cultured, Medicine(all), Viral Vaccine, Cross-presentation, Herpes Simplex, Viral Vaccines, General Medicine, Middle Aged, Virology, Herpes simplex virus, medicine.anatomical_structure, Technical Advance, Immunology, Female, Corrigendum, CD8

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a769c9727dc1284d26cc58bfadeb7ba7Test
https://doi.org/10.1172/jci60556Test

المؤلفون: Bertrand Knebelmann, Gérard Friedlander, Tak W. Mak, Jonathan Barasch, Thorsten Berger, Clément Nguyen, Evangeline Pillebout, Kiyoshi Mori, Amandine Viau, Denise Laouari, Martine Burtin, Khalil El Karoui, Fabiola Terzi

المصدر: Journal of Clinical Investigation. 120:4065-4076

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Mice, Inbred Strains, Nephron, Biology, Lipocalin, urologic and male genital diseases, Cell Line, Lesion, Mice, Young Adult, Lipocalin-2, Downregulation and upregulation, Epidermal growth factor, Proto-Oncogene Proteins, Internal medicine, medicine, Polycystic kidney disease, Animals, Humans, Renal Insufficiency, Chronic, Aged, Mice, Knockout, Oncogene Proteins, Polycystic Kidney Diseases, Epidermal Growth Factor, Acute-phase protein, General Medicine, Middle Aged, Hypoxia-Inducible Factor 1, alpha Subunit, medicine.disease, Lipocalins, ErbB Receptors, medicine.anatomical_structure, Endocrinology, Disease Progression, Female, medicine.symptom, Acute-Phase Proteins, Research Article, Kidney disease

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cb596419bb714ec75a9ac6c20de964bTest
https://doi.org/10.1172/jci42004Test