نتائج البحث

1

CD4+CD25+CD127hi cell frequency predicts disease progression in type 1 diabetes

المؤلفون: Mark Harris, Ranjeny Thomas, Martin J. Hessner, Rhonda Geoffrey, Anne-Sophie Bergot, Breanna Lam, Kerry Buchanan, Elisavet Serti, Rosita Moya, Alessandra Mandelli, Irene Gotuzzo, Manuela Battaglia, Joanna D. Davies, Aditi Narsale, Benedetta Pessina, Gian Maria Giamporcaro, TingTing Lu

المصدر: JCI Insight, Vol 6, Iss 2 (2021)
JCI Insight

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Male, 0301 basic medicine, Oncology, Autoimmune diseases, medicine.medical_treatment, Cell, Autoimmunity, medicine.disease_cause, 0302 clinical medicine, T-Lymphocyte Subsets, IL-2 receptor, Child, education.field_of_study, Diabetes, General Medicine, medicine.anatomical_structure, Child, Preschool, 030220 oncology & carcinogenesis, Disease Progression, Medicine, Female, Immunotherapy, Research Article, medicine.drug, Adult, medicine.medical_specialty, Adolescent, Population, Immunology, T cells, Alefacept, Interleukin-7 Receptor alpha Subunit, Young Adult, 03 medical and health sciences, Diabetes mellitus, Internal medicine, medicine, Humans, education, Proportional Hazards Models, Type 1 diabetes, business.industry, Interleukin-2 Receptor alpha Subunit, Infant, medicine.disease, Diabetes Mellitus, Type 1, 030104 developmental biology, Multivariate Analysis, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b18ca9272dda4aa45bece327b8ae55f8Test
https://doaj.org/article/20ba8c4ce6b4454ea7c69dca229e3557Test

2

Chromosome 8 gain is associated with high-grade transformation in MPNST

المصدر: JCI Insight, Vol 6, Iss 6 (2021)
JCI Insight

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75196857babffae439e3abe5a5613bbdTest
https://doaj.org/article/02174fc3c80343d29dc12bc04c3f1439Test

3

CD19 CAR T cell product and disease attributes predict leukemia remission durability

المؤلفون: Hannah Brakke, Olivia Finney, Roxana Hicks, Daniel Li, Stephanie Rawlings-Rhea, Rebecca Gardner, Ben Futrell, Marisa Lopez, Michael C. Jensen, Rimas J. Orentas, Danielle Doolittle

المصدر: J Clin Invest

مصطلحات موضوعية: Male, 0301 basic medicine, Oncology, Adoptive cell transfer, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Kaplan-Meier Estimate, Hematopoietic stem cell transplantation, CD8-Positive T-Lymphocytes, Lymphocyte Activation, Immunotherapy, Adoptive, 0302 clinical medicine, Recurrence, Cytotoxic T cell, Child, Hepatitis A Virus Cellular Receptor 2, Leukemia, Receptors, Chimeric Antigen, Gene Expression Regulation, Leukemic, Remission Induction, Hematopoietic Stem Cell Transplantation, General Medicine, Aplasia, Lymphocyte Activation Gene 3 Protein, Phenotype, medicine.anatomical_structure, Child, Preschool, 030220 oncology & carcinogenesis, Female, Adult, medicine.medical_specialty, Adolescent, Antigens, CD19, Disease-Free Survival, Immunophenotyping, Young Adult, 03 medical and health sciences, Antigen, Antigens, CD, Internal medicine, medicine, Humans, B cell, Cell Proliferation, Tumor Necrosis Factor-alpha, business.industry, Infant, medicine.disease, Chimeric antigen receptor, 030104 developmental biology, Commentary, K562 Cells, business, CD8

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a113c5e07f7fbde58d76de414a97babfTest
https://doi.org/10.1172/jci125423Test

4

Profiling of patients with glioma reveals the dominant immunosuppressive axis is refractory to immune function restoration

المصدر: JCI Insight
JCI Insight, Vol 5, Iss 17 (2020)

مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Cancer immunotherapy, Brain cancer, Mice, 0302 clinical medicine, 5'-Nucleotidase, Immune Checkpoint Inhibitors, Cells, Cultured, Brain Neoplasms, Apyrase, Glioma, General Medicine, Middle Aged, Isocitrate Dehydrogenase, Oncology, 030220 oncology & carcinogenesis, Medicine, Female, Immunosuppressive Agents, Research Article, medicine.drug, Adult, IDH1, Receptor, Adenosine A2A, Immunology, 03 medical and health sciences, Immune system, Downregulation and upregulation, Antigens, CD, Cell Line, Tumor, medicine, Animals, Humans, Aged, business.industry, Therapeutic effect, medicine.disease, Adenosine, Adenosine receptor, Mice, Inbred C57BL, 030104 developmental biology, Cancer research, Neoplasm Grading, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1b7362d1d0c19278cd2192b48b6dbf5Test
https://doi.org/10.1172/jci.insight.134386Test

5

Ovarian granulosa cell tumor characterization identifies FOXL2 as an immunotherapeutic target

المؤلفون: Mark A. Morgan, Robert A. Burger, Mireia Uribe-Herranz, Stefano Pierini, Erin George, Fiona Simpkins, Janos L. Tanyi, Andrea Facciabene, Ronny Drapkin

المصدر: JCI Insight, Vol 5, Iss 16 (2020)
JCI Insight

مصطلحات موضوعية: 0301 basic medicine, Adult, Forkhead Box Protein L2, medicine.medical_treatment, Population, Programmed Cell Death 1 Receptor, Immunology, Immune Targeting, Cancer immunotherapy, Mice, Inbred Strains, Cancer Vaccines, 03 medical and health sciences, Epitopes, 0302 clinical medicine, Immune system, Lymphocytes, Tumor-Infiltrating, Pregnancy, Cell Line, Tumor, Immune Tolerance, Tumor Microenvironment, Vaccines, DNA, Medicine, Animals, Humans, education, Immune Checkpoint Inhibitors, Granulosa Cell Tumor, education.field_of_study, business.industry, Tumor-infiltrating lymphocytes, General Medicine, Middle Aged, Xenograft Model Antitumor Assays, 030104 developmental biology, Forkhead box L2, Immunization, Oncology, Tumor progression, 030220 oncology & carcinogenesis, Cancer research, Female, business, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::255c99bb3ed436759c3786738dc4cef4Test
https://doaj.org/article/3ee8feab99b74b3781439e0dd4109565Test

6

Universal monitoring of minimal residual disease in acute myeloid leukemia

المؤلفون: Jeffrey E. Rubnitz, Ching-Hon Pui, Dario Campana, Siew Peng Chen, Allen Eng Juh Yeoh, Elaine Coustan-Smith, Wee Joo Chng, James R. Downing, Guangchun Song, Sheila A. Shurtleff

المصدر: JCI Insight. 3

مصطلحات موضوعية: Adult, 0301 basic medicine, Oncology, medicine.medical_specialty, Neoplasm, Residual, Adolescent, CD52, CD34, Gene Expression, Antigens, CD34, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Antigens, CD, hemic and lymphatic diseases, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, Biomarkers, Tumor, medicine, Humans, Granulocyte Precursor Cells, Child, neoplasms, Monitoring, Physiologic, Hematology, business.industry, Gene Expression Profiling, Infant, Membrane Proteins, Myeloid leukemia, Cancer, General Medicine, Middle Aged, medicine.disease, ADP-ribosyl Cyclase 1, Minimal residual disease, body regions, Leukemia, Myeloid, Acute, Leukemia, 030104 developmental biology, medicine.anatomical_structure, Case-Control Studies, Child, Preschool, 030220 oncology & carcinogenesis, Disease Progression, Bone marrow, Clinical Medicine, business, Algorithms

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33c5aa23d454169d93e1d1c1d99d9e15Test
https://doi.org/10.1172/jci.insight.98561Test

7

Frameshift events predict anti–PD-1/L1 response in head and neck cancer

المؤلفون: Ravindra Uppaluri, Jochen H. Lorch, Alexander Frieden, Frank C. Kuo, Glenn J. Hanna, Megan E. Cavanaugh, Jonathan D. Schoenfeld, Patrick H. Lizotte, Robert I. Haddad, Nicole G. Chau, Laura E. MacConaill, Priyanka Shivdasani

المصدر: JCI Insight, Vol 3, Iss 4 (2018)

مصطلحات موضوعية: Male, 0301 basic medicine, Oncology, Biopsy, medicine.medical_treatment, DNA Mutational Analysis, Programmed Cell Death 1 Receptor, lcsh:Medicine, B7-H1 Antigen, Antineoplastic Agents, Immunological, 0302 clinical medicine, Mutation Rate, Genes, Tumor Suppressor, Prospective Studies, Frameshift Mutation, Prospective cohort study, Aged, 80 and over, General Medicine, Middle Aged, Prognosis, Neoadjuvant Therapy, Treatment Outcome, medicine.anatomical_structure, Head and Neck Neoplasms, 030220 oncology & carcinogenesis, Female, Research Article, Adult, medicine.medical_specialty, T cell, Frameshift mutation, Young Adult, 03 medical and health sciences, Internal medicine, Biomarkers, Tumor, Genetics, medicine, Humans, Survival analysis, Aged, Chemotherapy, Squamous Cell Carcinoma of Head and Neck, business.industry, lcsh:R, Head and neck cancer, Immunotherapy, medicine.disease, Survival Analysis, Otorhinolaryngologic Surgical Procedures, 030104 developmental biology, Drug Resistance, Neoplasm, business, CD8

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d14182187ffb2939faf895230365f8bTest
https://doi.org/10.1172/jci.insight.98811Test

8

Development of MK-8353, an orally administered ERK1/2 inhibitor, in patients with advanced solid tumors

المصدر: JCI Insight, Vol 3, Iss 4 (2018)
JCI insight, vol 3, iss 4

مصطلحات موضوعية: 0301 basic medicine, Male, Pyrrolidines, Pyridines, Drug Evaluation, Preclinical, Administration, Oral, Phases of clinical research, lcsh:Medicine, Pharmacology, Signal transduction, Mice, 0302 clinical medicine, Clinical trials, Neoplasms, Medicine, Melanoma, Fatigue, Cancer, Mitogen-Activated Protein Kinase 1, Tumor, Mitogen-Activated Protein Kinase 3, Nausea, General Medicine, Middle Aged, Preclinical, Tolerability, Oncology, 030220 oncology & carcinogenesis, 6.1 Pharmaceuticals, Toxicity, Administration, Female, Drug Eruptions, Drug, Diarrhea, Oral, Adult, Indazoles, Maximum Tolerated Dose, MAP Kinase Signaling System, Clinical Trials and Supportive Activities, Biological Availability, Cell Line, Dose-Response Relationship, 03 medical and health sciences, Young Adult, Dogs, Pharmacokinetics, Clinical Research, Cell Line, Tumor, Animals, Humans, Clinical Trials, Adverse effect, Protein Kinase Inhibitors, Neoplasm Staging, Dose-Response Relationship, Drug, business.industry, lcsh:R, Evaluation of treatments and therapeutic interventions, Triazoles, medicine.disease, Xenograft Model Antitumor Assays, Rats, Clinical trial, 030104 developmental biology, Pharmacodynamics, Drug Evaluation, Clinical Medicine, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f1125084220541ce8d767feec5c05a4Test
https://doaj.org/article/675b9e9f9e9e4e0f87e9c28de4f3db4bTest

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