نتائج البحث

1

SARS–CoV-2–specific T cell responses and correlations with COVID-19 patient predisposition

المؤلفون: Katrin Moira Heim, Martin E. Kreis, Stefan Angermair, Fabian Halleck, Arne Sattler, Katja Kotsch, Helena Stockmann, Dmytro Khadzhynov, Sascha Treskatsch

المصدر: J Clin Invest

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e03688bab38d81eca8efbaf0e659dfaTest
https://doi.org/10.1172/jci140965Test

2

GLS1-mediated glutaminolysis unbridled by MALT1 protease promotes psoriasis pathogenesis

المؤلفون: Peng Li, Leqing Zhu, Liehua Deng, Zhizhong Li, Hua Zhang, Yueqi Song, Xichun Xia, Jianlei Hao, Xiao Wang, Chengbin Guo, Zhinan Yin, Guangchao Cao, Yixia Tian, Wei Zhou, Yunfei Gao, Jingxiang Zhong, Guodong Sun

المصدر: J Clin Invest

مصطلحات موضوعية: Adult, Keratinocytes, Male, 0301 basic medicine, Chemokine, Glutamine, Cellular differentiation, medicine.disease_cause, Autoimmunity, Mice, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Glutaminase, T-Lymphocyte Subsets, Psoriasis, medicine, Animals, Humans, RNA, Messenger, Histone H3 acetylation, Aged, Mice, Knockout, Glutaminolysis, biology, Chemistry, Interleukin-17, Cell Differentiation, General Medicine, Middle Aged, medicine.disease, Mice, Inbred C57BL, Disease Models, Animal, MALT1, 030104 developmental biology, Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein, Case-Control Studies, 030220 oncology & carcinogenesis, biology.protein, Cancer research, Th17 Cells, Female, IL17A, Metabolic Networks and Pathways, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1f6d904955d64d82e287033ac565778Test
https://doi.org/10.1172/jci129269Test

3

Fatty acid binding protein 4 promotes autoimmune diabetes by recruitment and activation of pancreatic islet macrophages

المؤلفون: Lai Yee Cheong, Ruby L. C. Hoo, Xiaoyu Xiao, Yang Liu, Yang Xiao, Zhiguang Zhou, Boya Liao, Aimin Xu, Xiaoping Wu, Lingling Shu

المصدر: JCI Insight, Vol 6, Iss 7 (2021)
JCI Insight

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Adoptive cell transfer, T-Lymphocytes, Autoimmunity, medicine.disease_cause, Fatty Acid-Binding Proteins, Diabetes Mellitus, Experimental, 03 medical and health sciences, Islets of Langerhans, 0302 clinical medicine, Immune system, Endocrinology, Mice, Inbred NOD, Medicine, Animals, Humans, Benzothiazoles, NOD mice, Autoantibodies, Bone Marrow Transplantation, Innate immunity, Type 1 diabetes, geography, geography.geographical_feature_category, Innate immune system, business.industry, Macrophages, Diabetes, Autoantibody, General Medicine, Carbocyanines, Middle Aged, medicine.disease, Islet, Mice, Mutant Strains, 030104 developmental biology, Diabetes Mellitus, Type 1, 030220 oncology & carcinogenesis, Immunology, Female, business, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b49e44f810f16457012d14ea324cf550Test
https://doaj.org/article/4cae76f959a34aa7a137d440a57963ccTest

4

Brain functions and cognition on transient insulin deprivation in type 1 diabetes

المؤلفون: John D. Port, Tiffany Cortes, Gregory N. Ruegsegger, Ana L. Creo, Andrea R.S. Huebner, Yogish C. Kudva, Aida N. Lteif, Katherine A. Klaus, Surendra Dasari, K. Sreekumaran Nair, Hang Joon Jo, Ronald C. Petersen, Jan Mendelt Tillema

المصدر: JCI Insight, Vol 6, Iss 5 (2021)
JCI Insight

مصطلحات موضوعية: Adult, Blood Glucose, Male, 0301 basic medicine, medicine.medical_specialty, medicine.medical_treatment, Pilot Projects, Phosphocreatine, Young Adult, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, Memory, Diabetes mellitus, Internal medicine, Fractional anisotropy, medicine, Insulin, Humans, Dementia, Cognitive Dysfunction, Sensory cortex, Translational Science, Biomedical, Type 1 diabetes, business.industry, Diabetes, Cognition, Somatosensory Cortex, General Medicine, medicine.disease, Diabetes Mellitus, Type 1, 030104 developmental biology, medicine.anatomical_structure, chemistry, 030220 oncology & carcinogenesis, Medicine, Female, Clinical Medicine, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df35e605fd35bca18e9e9717df343f45Test
https://doaj.org/article/89e91ea96c224a14803019bb961e2cc3Test

5

Is APOC3 the driver of cardiovascular disease in people with type I diabetes mellitus?

المؤلفون: Gissette Reyes-Soffer, Henry N. Ginsberg

المصدر: J Clin Invest

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Apolipoprotein E, medicine.medical_specialty, endocrine system diseases, Coronary Artery Disease, Disease, Diabetes Mellitus, Experimental, Oligodeoxyribonucleotides, Antisense, Coronary artery disease, Mice, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, Internal medicine, Diabetes mellitus, medicine, Animals, Humans, Prospective Studies, Vascular Calcification, Triglycerides, Mice, Knockout, Apolipoprotein C-III, Type 1 diabetes, Lipoprotein lipase, business.industry, General Medicine, Middle Aged, Atherosclerosis, medicine.disease, Diabetes Mellitus, Type 1, 030104 developmental biology, Endocrinology, Cardiovascular Diseases, 030220 oncology & carcinogenesis, Commentary, Female, Apolipoprotein C3, business, Research Article, Foam Cells

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0749743924d73a885f0d02c9ccc83a9bTest
https://doi.org/10.1172/jci131333Test

6

CD4+CD25+CD127hi cell frequency predicts disease progression in type 1 diabetes

المؤلفون: Mark Harris, Ranjeny Thomas, Martin J. Hessner, Rhonda Geoffrey, Anne-Sophie Bergot, Breanna Lam, Kerry Buchanan, Elisavet Serti, Rosita Moya, Alessandra Mandelli, Irene Gotuzzo, Manuela Battaglia, Joanna D. Davies, Aditi Narsale, Benedetta Pessina, Gian Maria Giamporcaro, TingTing Lu

المصدر: JCI Insight, Vol 6, Iss 2 (2021)
JCI Insight

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Male, 0301 basic medicine, Oncology, Autoimmune diseases, medicine.medical_treatment, Cell, Autoimmunity, medicine.disease_cause, 0302 clinical medicine, T-Lymphocyte Subsets, IL-2 receptor, Child, education.field_of_study, Diabetes, General Medicine, medicine.anatomical_structure, Child, Preschool, 030220 oncology & carcinogenesis, Disease Progression, Medicine, Female, Immunotherapy, Research Article, medicine.drug, Adult, medicine.medical_specialty, Adolescent, Population, Immunology, T cells, Alefacept, Interleukin-7 Receptor alpha Subunit, Young Adult, 03 medical and health sciences, Diabetes mellitus, Internal medicine, medicine, Humans, education, Proportional Hazards Models, Type 1 diabetes, business.industry, Interleukin-2 Receptor alpha Subunit, Infant, medicine.disease, Diabetes Mellitus, Type 1, 030104 developmental biology, Multivariate Analysis, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b18ca9272dda4aa45bece327b8ae55f8Test
https://doaj.org/article/20ba8c4ce6b4454ea7c69dca229e3557Test

7

PAHSAs attenuate immune responses and promote β cell survival in autoimmune diabetic mice

المؤلفون: Maria Fernandez Rubin De Celis, Diane Mathis, Archana Vijayakumar, Pedro M. Moraes-Vieira, Dionicio Siegel, Alan Saghatelian, Ismail Syed, James F. Mohan, Barbara B. Kahn, Andrew T. Nelson

المصدر: J Clin Invest

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, endocrine system, medicine.medical_specialty, endocrine system diseases, Cell Survival, T-Lymphocytes, T cell, Palmitic Acid, Nod, Diabetes Mellitus, Experimental, Islets of Langerhans, Mice, 03 medical and health sciences, 0302 clinical medicine, Immune system, Mice, Inbred NOD, Insulin-Secreting Cells, Internal medicine, medicine, Animals, Humans, Insulin, B cell, Aged, NOD mice, Cell growth, Chemistry, Esters, General Medicine, Glucose Tolerance Test, Middle Aged, medicine.disease, Diabetes Mellitus, Type 1, 030104 developmental biology, Endocrinology, medicine.anatomical_structure, Immune System, 030220 oncology & carcinogenesis, Commentary, Female, Insulitis, Stearic Acids, CD8

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::499e34da0668ce296976fc5094ee51f3Test
https://doi.org/10.1172/jci122445Test

8

Phenotypic heterogeneity of neurofibromatosis type 1 in a large international registry

المؤلفون: Shufeng Li, Annette Bakker, Kavita Y. Sarin, Mika M. Tabata, Pamela Knight

المصدر: JCI Insight, Vol 5, Iss 16 (2020)
JCI Insight

مصطلحات موضوعية: 0301 basic medicine, Adult, Pathology, medicine.medical_specialty, congenital, hereditary, and neonatal diseases and abnormalities, Neurofibromatosis 1, Adolescent, Malignant peripheral nerve sheath tumor, Comorbidity, Dermatology, Spinal neurofibromas, 03 medical and health sciences, Young Adult, 0302 clinical medicine, medicine, Prevalence, Neurofibroma, Humans, Genetic variation, Registries, Neurofibromatosis, neoplasms, Aged, Neurofibromin 1, business.industry, Genetic heterogeneity, Genetic disorder, General Medicine, Phenotypic trait, Middle Aged, medicine.disease, nervous system diseases, 030104 developmental biology, Phenotype, Dysplasia, 030220 oncology & carcinogenesis, Mutation, Medicine, business, Neurological disorders, Research Article, Genetic diseases, Neuroscience

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b2985be0c1f54c8a1ca7f5cb518d27dTest
https://doaj.org/article/097c0850c842415abb2e9486dc716821Test

9

Pancreas tissue slices from organ donors enable in situ analysis of type 1 diabetes pathogenesis

المصدر: JCI insight 5:134525 (2020)
JCI Insight

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Cell physiology, endocrine system, Pathology, medicine.medical_specialty, Adolescent, endocrine system diseases, Cell, Enteroendocrine cell, medicine.disease_cause, Autoimmunity, Tissue Culture Techniques, Pathogenesis, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Insulin-Secreting Cells, Diabetes mellitus, medicine, Humans, Child, Pancreas, Autoimmune Diseases, Beta Cells, Diabetes, Endocrinology, Type 1 diabetes, business.industry, General Medicine, medicine.disease, Tissue Donors, Diabetes Mellitus, Type 1, 030104 developmental biology, medicine.anatomical_structure, Technical Advance, Child, Preschool, 030220 oncology & carcinogenesis, Female, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f63476339e1164c9eeceb0ad18778170Test
https://doi.org/10.1172/jci.insight.134525Test

10

High residual C-peptide likely contributes to glycemic control in type 1 diabetes

المؤلفون: Carla J. Greenbaum, Alyssa Ylescupidez, Carmella Evans-Molina, Viral N. Shah, Kellee M. Miller, Wei Hao, Kristen J. Nadeau, Jennifer L. Sherr, Henry T. Bahnson, Tamara S. Hannon, Michael R. Rickels, Mark A. Clements, Richard E. Pratley

المصدر: J Clin Invest

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67de680e736dd9c6feea057f91663ed1Test
https://europepmc.org/articles/PMC7108933Test/

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