نتائج البحث

1

Brain functions and cognition on transient insulin deprivation in type 1 diabetes

المؤلفون: John D. Port, Tiffany Cortes, Gregory N. Ruegsegger, Ana L. Creo, Andrea R.S. Huebner, Yogish C. Kudva, Aida N. Lteif, Katherine A. Klaus, Surendra Dasari, K. Sreekumaran Nair, Hang Joon Jo, Ronald C. Petersen, Jan Mendelt Tillema

المصدر: JCI Insight, Vol 6, Iss 5 (2021)
JCI Insight

مصطلحات موضوعية: Adult, Blood Glucose, Male, 0301 basic medicine, medicine.medical_specialty, medicine.medical_treatment, Pilot Projects, Phosphocreatine, Young Adult, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, Memory, Diabetes mellitus, Internal medicine, Fractional anisotropy, medicine, Insulin, Humans, Dementia, Cognitive Dysfunction, Sensory cortex, Translational Science, Biomedical, Type 1 diabetes, business.industry, Diabetes, Cognition, Somatosensory Cortex, General Medicine, medicine.disease, Diabetes Mellitus, Type 1, 030104 developmental biology, medicine.anatomical_structure, chemistry, 030220 oncology & carcinogenesis, Medicine, Female, Clinical Medicine, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df35e605fd35bca18e9e9717df343f45Test
https://doaj.org/article/89e91ea96c224a14803019bb961e2cc3Test

2

High residual C-peptide likely contributes to glycemic control in type 1 diabetes

المؤلفون: Carla J. Greenbaum, Alyssa Ylescupidez, Carmella Evans-Molina, Viral N. Shah, Kellee M. Miller, Wei Hao, Kristen J. Nadeau, Jennifer L. Sherr, Henry T. Bahnson, Tamara S. Hannon, Michael R. Rickels, Mark A. Clements, Richard E. Pratley

المصدر: J Clin Invest

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67de680e736dd9c6feea057f91663ed1Test
https://europepmc.org/articles/PMC7108933Test/

3

Hypoglycemia unawareness in type 1 diabetes suppresses brain responses to hypoglycemia

المؤلفون: Wai Lam, Janice J. Hwang, Robert S. Sherwin, Muhammad Hamza, Cheryl Lacadie, R. Todd Constable, Feng Dai, Dongju Seo, Renata Belfort-DeAguiar, Rajita Sinha, Anne-Sophie Sejling, Christian P. Schmidt, Lisa Parikh

المصدر: Journal of Clinical Investigation. 128:1485-1495

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36737dec8c9326f32c9e7d19e4698156Test
https://doi.org/10.1172/jci97696Test

4

Treg gene signatures predict and measure type 1 diabetes trajectory

المؤلفون: Virginia Chen, Jana Gillies, Tom Elliott, Cate Speake, Jan P. Dutz, Rusung Tan, Samuel Chow, Anne M. Pesenacker, Megan K. Levings, Scott J. Tebbutt, Ashish Marwaha, Annika C. Sun

مصطلحات موضوعية: 0301 basic medicine, Adult, Canada, endocrine system diseases, Adolescent, Genotype, medicine.medical_treatment, Single-nucleotide polymorphism, Type 2 diabetes, T-Lymphocytes, Regulatory, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Diabetes mellitus, medicine, Humans, RNA, Messenger, Biomarker discovery, Type 1 diabetes, business.industry, nutritional and metabolic diseases, Computational Biology, General Medicine, Immunotherapy, Gene signature, medicine.disease, 030104 developmental biology, Cross-Sectional Studies, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Gene Expression Regulation, 030220 oncology & carcinogenesis, Immunology, Leukocytes, Mononuclear, Biomarker (medicine), Clinical Medicine, business, Algorithms, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ab7a1938188d2442dcdaf0a45229969Test
https://europepmc.org/articles/PMC6483004Test/

5

β Cell dysfunction exists more than 5 years before type 1 diabetes diagnosis

المؤلفون: Heba M. Ismail, Jay M. Sosenko, Carmella Evans-Molina, Susan Geyer, Ping Xu, Jeffrey P. Krischer, Jerry P. Palmer, Linda A. DiMeglio, Emily K. Sims, Andrea K. Steck

المصدر: JCI Insight. 3

مصطلحات موضوعية: Adult, Blood Glucose, Male, 0301 basic medicine, endocrine system, Allergy, medicine.medical_specialty, Time Factors, endocrine system diseases, Adolescent, medicine.medical_treatment, Cell, 030209 endocrinology & metabolism, Child health, Young Adult, 03 medical and health sciences, 0302 clinical medicine, immune system diseases, Insulin-Secreting Cells, Internal medicine, Diabetes mellitus, medicine, Humans, Longitudinal Studies, Prospective Studies, Child, Autoantibodies, Type 1 diabetes, Kidney, C-Peptide, business.industry, Insulin, nutritional and metabolic diseases, Fasting, General Medicine, Glucose Tolerance Test, medicine.disease, Clinical trial, Diabetes Mellitus, Type 1, 030104 developmental biology, medicine.anatomical_structure, Child, Preschool, Disease Progression, Female, Clinical Medicine, business, Follow-Up Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e05157a96e533cd8bff8a2effe6bef0Test
https://doi.org/10.1172/jci.insight.120877Test

6

Combination of host immune metabolic biomarkers for the PD-1 blockade cancer immunotherapy

المؤلفون: Tasuku Honjo, Toyohiro Hirai, Yuichi Sakamori, Yasushi Okuno, Maryam Akrami, Fumihiko Matsuda, Ryusuke Hatae, Hiroaki Ozasa, Hironori Yoshida, Kazuhiro Sonomura, Kenji Chamoto, Kei Taneishi, Shuji Kawaguchi, Sidonia Fagarasan, Izuru Masuda, Young Hak Kim

المصدر: JCI Insight. 5

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Lung Neoplasms, Metabolite, medicine.medical_treatment, T cell, Programmed Cell Death 1 Receptor, 03 medical and health sciences, chemistry.chemical_compound, Antineoplastic Agents, Immunological, 0302 clinical medicine, Immune system, Cancer immunotherapy, Carcinoma, Non-Small-Cell Lung, Carnitine, Biomarkers, Tumor, Humans, Medicine, Prospective Studies, Beta oxidation, Aged, Aged, 80 and over, Glutathione Disulfide, business.industry, Hippurates, Microbiota, General Medicine, Middle Aged, Nivolumab, 030104 developmental biology, medicine.anatomical_structure, chemistry, 030220 oncology & carcinogenesis, Cancer research, Glutathione disulfide, Drug Therapy, Combination, Female, Immunotherapy, Clinical Medicine, Energy Metabolism, business, CD8

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0f8b83c0a144f9febe31ec1f05c62abTest
https://doi.org/10.1172/jci.insight.133501Test

7

Robust surgical approach for cutaneous neurofibroma in neurofibromatosis type 1

المؤلفون: Lu Q. Le, Juan Vega, Dezehree Solorzano, La’Nette Hernandez, Bahir H. Chamseddin

المصدر: JCI Insight. 4

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c671c7751016921538509ba54c5fc165Test
https://doi.org/10.1172/jci.insight.128881Test

8

Universal monitoring of minimal residual disease in acute myeloid leukemia

المؤلفون: Jeffrey E. Rubnitz, Ching-Hon Pui, Dario Campana, Siew Peng Chen, Allen Eng Juh Yeoh, Elaine Coustan-Smith, Wee Joo Chng, James R. Downing, Guangchun Song, Sheila A. Shurtleff

المصدر: JCI Insight. 3

مصطلحات موضوعية: Adult, 0301 basic medicine, Oncology, medicine.medical_specialty, Neoplasm, Residual, Adolescent, CD52, CD34, Gene Expression, Antigens, CD34, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Antigens, CD, hemic and lymphatic diseases, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, Biomarkers, Tumor, medicine, Humans, Granulocyte Precursor Cells, Child, neoplasms, Monitoring, Physiologic, Hematology, business.industry, Gene Expression Profiling, Infant, Membrane Proteins, Myeloid leukemia, Cancer, General Medicine, Middle Aged, medicine.disease, ADP-ribosyl Cyclase 1, Minimal residual disease, body regions, Leukemia, Myeloid, Acute, Leukemia, 030104 developmental biology, medicine.anatomical_structure, Case-Control Studies, Child, Preschool, 030220 oncology & carcinogenesis, Disease Progression, Bone marrow, Clinical Medicine, business, Algorithms

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33c5aa23d454169d93e1d1c1d99d9e15Test
https://doi.org/10.1172/jci.insight.98561Test

9

CD38+ M-MDSC expansion characterizes a subset of advanced colorectal cancer patients

المؤلفون: Jae W. Lee, Ayumi Hashimoto, Eric W. Lin, Christopher Chiu, Anil K. Rustgi, Dmitry I. Gabrilovich, George A. Dominguez, Tatiana A. Karakasheva, Gregory L. Beatty, Kate Sasser

المصدر: JCI Insight. 3

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Esophageal Neoplasms, Neutrophils, medicine.drug_class, Colorectal cancer, medicine.medical_treatment, Population, CD38, Monoclonal antibody, Peripheral blood mononuclear cell, Monocytes, Mice, 03 medical and health sciences, 0302 clinical medicine, Cancer immunotherapy, hemic and lymphatic diseases, medicine, Animals, Humans, Lymphocytes, education, Aged, education.field_of_study, Membrane Glycoproteins, business.industry, Myeloid-Derived Suppressor Cells, Antibodies, Monoclonal, Cancer, hemic and immune systems, General Medicine, Middle Aged, Pennsylvania, Esophageal cancer, medicine.disease, ADP-ribosyl Cyclase 1, 030104 developmental biology, 030220 oncology & carcinogenesis, Leukocytes, Mononuclear, Cancer research, Female, Clinical Medicine, Colorectal Neoplasms, business, Immunosuppressive Agents

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a7edd68d504169128a73fc61f7bad94Test
https://doi.org/10.1172/jci.insight.97022Test

10

Development of MK-8353, an orally administered ERK1/2 inhibitor, in patients with advanced solid tumors

المصدر: JCI Insight, Vol 3, Iss 4 (2018)
JCI insight, vol 3, iss 4

مصطلحات موضوعية: 0301 basic medicine, Male, Pyrrolidines, Pyridines, Drug Evaluation, Preclinical, Administration, Oral, Phases of clinical research, lcsh:Medicine, Pharmacology, Signal transduction, Mice, 0302 clinical medicine, Clinical trials, Neoplasms, Medicine, Melanoma, Fatigue, Cancer, Mitogen-Activated Protein Kinase 1, Tumor, Mitogen-Activated Protein Kinase 3, Nausea, General Medicine, Middle Aged, Preclinical, Tolerability, Oncology, 030220 oncology & carcinogenesis, 6.1 Pharmaceuticals, Toxicity, Administration, Female, Drug Eruptions, Drug, Diarrhea, Oral, Adult, Indazoles, Maximum Tolerated Dose, MAP Kinase Signaling System, Clinical Trials and Supportive Activities, Biological Availability, Cell Line, Dose-Response Relationship, 03 medical and health sciences, Young Adult, Dogs, Pharmacokinetics, Clinical Research, Cell Line, Tumor, Animals, Humans, Clinical Trials, Adverse effect, Protein Kinase Inhibitors, Neoplasm Staging, Dose-Response Relationship, Drug, business.industry, lcsh:R, Evaluation of treatments and therapeutic interventions, Triazoles, medicine.disease, Xenograft Model Antitumor Assays, Rats, Clinical trial, 030104 developmental biology, Pharmacodynamics, Drug Evaluation, Clinical Medicine, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f1125084220541ce8d767feec5c05a4Test
https://doaj.org/article/675b9e9f9e9e4e0f87e9c28de4f3db4bTest

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