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1دورية أكاديمية
المؤلفون: Feole Monica
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: Alzheimer’s disease, axonal transport, familial pathogenic variants, amyloid precursor protein, dynactin-1, early endosomes, lysosomes, Alzheimerova choroba, axonální transport, familiární patogenní varianty, amyloidní prekurzorový protein, dynaktin-1, časné endozomy, lysozomy
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2دورية أكاديمية
المؤلفون: Kurth, Vanessa, Ogorek, Isabella, Münch, Carolina, López-Ríos, Javier, Ousson, Solenne, Lehmann, Sandra, Nieweg, Katja, Roebroek, Anton J.M., Pietrzik, Claus U., Beher, Dirk, Weggen, Sascha
المساهمون: Alzheimer Forschung Initiative, German Research Foundation
مصطلحات موضوعية: Alzheimer disease, Amyloid-beta (Aβ), Amyloid precursor protein (APP), Presenilin, Mutant, Gamma-secretase, Genome engineering, Recombination, Embryonic stem cell
وصف الملف: application/pdf
العلاقة: Publisher's version; http://dx.doi.org/10.1016/j.jbc.2023.104997Test; Sí; e-issn: 1083-351X; Journal of Biological Chemistry 299: 104997 (2023); http://hdl.handle.net/10261/341879Test; http://dx.doi.org/10.13039/501100001659Test
الإتاحة: https://doi.org/10.1016/j.jbc.2023.104997Test
https://doi.org/10.13039/501100001659Test
http://hdl.handle.net/10261/341879Test -
3
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: amyloid precursor protein (APP), Cell Membrane, amyloid-beta (Aβ), neurodegeneration, APP-CTF, meprin β, ADAM, Metalloendopeptidases, Alzheimer's disease, Matrix Metalloproteinase Inhibitors, Cell Line, ADAM10 Protein, Amyloid beta-Protein Precursor, Phosphoserine, Neurobiology, proteolytic processing, Cell Line, Tumor, mental disorders, Humans, β-secretase 1 (BACE1), Amyloid Precursor Protein Secretases, Phosphorylation, Protein Processing, Post-Translational
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::220f2700be710fde5d193332c6474a94Test
http://europepmc.org/articles/PMC6879340Test -
4دورية أكاديمية
المؤلفون: Bussiere, Renaud, Lacampagne, Alain, Reiken, Steven, Liu, Xiaoping, Scheuerman, Valerie, Zalk, Ran, Martin, Cécile, Checler, Frédéric, Marks, Andrew, Chami, Mounia
المساهمون: Institut de pharmacologie moléculaire et cellulaire (IPMC), Université Nice Sophia Antipolis (1965 - 2019) (UNS)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA), Physiologie & médecine expérimentale du Cœur et des Muscles U 1046 (PhyMedExp), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Department of Physiology & Cellular Biophysics, Columbia University New York
المصدر: ISSN: 0021-9258.
مصطلحات موضوعية: Alzheimer disease, amyloid precursor protein (APP), amyloid-β (AB), calcium intracellular release, calstabin2, ryanodine receptor, β 2 adrenergic signaling, [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology
العلاقة: info:eu-repo/semantics/altIdentifier/pmid/28476886; hal-01827807; https://hal.umontpellier.fr/hal-01827807Test; https://hal.umontpellier.fr/hal-01827807/documentTest; https://hal.umontpellier.fr/hal-01827807/file/2017%20Bussiere%20et%20al.,%20Amyloid%20beta%20production.pdfTest; PUBMED: 28476886
الإتاحة: https://doi.org/10.1074/jbc.M116.743070Test
https://hal.umontpellier.fr/hal-01827807Test
https://hal.umontpellier.fr/hal-01827807/documentTest
https://hal.umontpellier.fr/hal-01827807/file/2017%20Bussiere%20et%20al.,%20Amyloid%20beta%20production.pdfTest -
5دورية أكاديمية
المؤلفون: Williamson, Rebecca L., Laulagnier, Karine, Miranda, André M., Fernandez, Marty A., Wolfe, Michael S., Sadoul, Rémy, Di Paolo, Gilbert
مصطلحات موضوعية: Amyloid beta-Peptides, Amyloid beta-Protein Precursor, Arginine, Cell Line, Endosomes, Humans, Lysine, Mutation, Peptide Fragments, Presenilin-2, Proteolysis, Ubiquitination, Alzheimer disease, amyloid precursor protein (APP), amyloid- (A), endosome, intracellular processing, intracellular trafficking, lysosome, presenilin, Science & Technology
وصف الملف: application/pdf
العلاقة: http://hdl.handle.net/1822/62019Test
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6
المؤلفون: Kara Molesworth, Olga Mychko, Ilia V. Baskakov, Natallia Makarava, Olga V. Bocharova, Narayan P. Pandit, Aidan Fisher
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, Aβ, β-amyloid, microglia, amyloid precursor protein, medicine.disease_cause, Biochemistry, Mice, Multiplicity of infection, Genotype, Amyloid precursor protein, 5XFAD mice, MOI, multiplicity of infection, Plaque-forming unit, PS1, presenilin 1, Microglia, Editors' Pick, Amyloidosis, HHV6 and HHV7, human herpesviruses 6 and 7, medicine.anatomical_structure, LD, lethal dose, herpes simplex virus 1, HSV-1, herpes simplex virus 1, Alzheimer’s disease, Research Article, Biology, AD, Alzheimer’s disease, CNS, central nervous system, Presenilin, 03 medical and health sciences, APP, amyloid precursor protein, Alzheimer Disease, HSE, herpes simplex encephalitis, medicine, Animals, Molecular Biology, Amyloid beta-Peptides, 030102 biochemistry & molecular biology, IC, intracranially, Wild type, Aβ aggregates, astrocytes, GFAP, glial fibrillary acidic protein, Herpes Simplex, Cell Biology, Virology, WT, wild-type, 030104 developmental biology, Herpes simplex virus, biology.protein, PFU, plaque-forming unit
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2ae24230b04d4f7e95d10a7a69a49edTest
http://europepmc.org/articles/PMC8214219Test -
7
المؤلفون: Dennis J. Selkoe, Lei Liu, Michael S. Wolfe, Bianca M. Lauro
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, FAD, familial Alzheimer’s disease, HL-1, hydrophilic loop-1, Amyloid beta, Allosteric regulation, TMD, transmembrane domain, γ-secretase, AD, Alzheimer’s disease, Biochemistry, Presenilin, DMEM, Dulbecco’s modified Eagle’s medium, Substrate Specificity, 03 medical and health sciences, Amyloid beta-Protein Precursor, FBS, fetal bovine serum, Protein Domains, APP, amyloid precursor protein, Alzheimer Disease, Amyloid precursor protein, Presenilin-1, Humans, Genetic Predisposition to Disease, Molecular Biology, γ-secretase modulator, Cells, Cultured, Aβ, GSM, γ-secretase modulator, CM, conditioned media, Amyloid beta-Peptides, 030102 biochemistry & molecular biology, biology, Chemistry, Rational design, Cell Biology, Processivity, Transmembrane protein, Cell biology, Aβ, amyloid-beta, Transmembrane domain, 030104 developmental biology, PS1, presenilin-1, Mutation, Proteolysis, biology.protein, HMW, high-molecular-weight, Amyloid Precursor Protein Secretases, Alzheimer’s disease, Research Article
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::534c8ae904c2652969945c575f9df201Test
http://europepmc.org/articles/PMC7961089Test -
8
المؤلفون: Philip Robinson, Neil J. Bulleid, Xiaofei Cao, Shingo Kanemura
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Protein Folding, Time Factors, folded precursor model, Endoplasmic Reticulum, Biochemistry, Protein Structure, Secondary, ADAM10 Protein, Protein structure, 0302 clinical medicine, quasi-stochastic model, Disulfides, Protein disulfide-isomerase, Protein secondary structure, protein homeostasis, 0303 health sciences, protein translocation, Oxidative folding, Translocon, protein disulfide isomerase, endoplasmic reticulum (ER), Folding (chemistry), Protein Structure and Folding, Protein folding, Protein domain, Context (language use), nascent chain, 03 medical and health sciences, Protein Domains, protein secretion, Animals, Humans, Cysteine, protein structure, Molecular Biology, 030304 developmental biology, Stochastic Processes, 030102 biochemistry & molecular biology, Endoplasmic reticulum, Membrane Proteins, Cell Biology, Prolactin, 030104 developmental biology, Biophysics, Cattle, Amyloid Precursor Protein Secretases, beta 2-Microglobulin, Ribosomes, 030217 neurology & neurosurgery, disulfide
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76b67b2902a1bd467f7ec772fccbb79dTest
http://europepmc.org/articles/PMC7039548Test -
9
المؤلفون: Michael R. Sierks, Ping He, Philip Schulz
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, Protein Conformation, Biochemistry, Mice, Amyloid precursor protein, scFv, single chain antibody variable domain fragment, Neurons, biology, Chemistry, oligomeric beta amyloid, Neurogenesis, DCX, doublecortin, Brain, Editors' Pick, Alzheimer's disease, Cell biology, BBB, blood brain barrier, medicine.anatomical_structure, Disease Progression, SYP, synaptophysin, AD, Alzheimer's disease, Intracellular, Research Article, Genetically modified mouse, Aβ, amyloid β, rAAV, recombinant human adeno-associated virus, transgenic mice, Blood–brain barrier, Protein Aggregation, Pathological, 03 medical and health sciences, MAP2, microtubule-associated protein 2, Alzheimer Disease, APP, amyloid precursor protein, medicine, Animals, Humans, ApoB, apolipoprotein B, Molecular Biology, Neuroinflammation, Amyloid beta-Peptides, 030102 biochemistry & molecular biology, GFAP, glial fibrillary acidic protein, Cell Biology, medicine.disease, neuron, Disease Models, Animal, ND, nondementia, 030104 developmental biology, single-chain antibody, biology.protein, Neuron, Single-Chain Antibodies
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb895cc10e4d58759d80fdf7e5d922ccTest
http://europepmc.org/articles/PMC7948963Test -
10
المؤلفون: Bettina Platt, Jochen Vogl, Nikolay Solovyev, Karima Schwab, Franz Theuring, Elizabeth Griffin, Frank Vanhaecke, Andrea Raab, Marta Costas-Rodríguez, Ahmed H. El-Khatib
المصدر: The Journal of Biological Chemistry
JOURNAL OF BIOLOGICAL CHEMISTRYمصطلحات موضوعية: 0301 basic medicine, Male, FTD, frontotemporal dementia, COPPER, Gene Expression, Protein aggregation, Biochemistry, CSF, cerebrospinal fluid, total element determination, ZINC, Amyloid beta-Protein Precursor, Mice, iron, Medicine and Health Sciences, Amyloid precursor protein, tau, Transgenes, Phosphorylation, BBB, blood–brain barrier, Isotope analysis, TRANSGENIC MICE, biology, zinc, MOUSE MODEL, AMYLOID-BETA, amyloid-beta, Chemistry, isotopic analysis, Tauopathy, ICP-MS, inductively coupled plasma–mass spectrometry, NEUROFIBRILLARY TANGLES, Alzheimer’s disease, Research Article, Genetically modified mouse, Amyloid beta, brain, Iron, chemistry.chemical_element, Mice, Transgenic, tau Proteins, Zinc, AD, Alzheimer’s disease, Presenilin, 03 medical and health sciences, Protein Aggregates, APP, amyloid precursor protein, Alzheimer Disease, medicine, Presenilin-1, Animals, multicollector inductively coupled plasma–mass spectrometry (ICP-MS), Molecular Biology, multi-collector inductively coupled plasma-mass spectrometry (ICP-MS), 030102 biochemistry & molecular biology, BLOOD-BRAIN-BARRIER, MUTATIONS, Spectrophotometry, Atomic, Biology and Life Sciences, Cell Biology, medicine.disease, WT, wild-type, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, METAL-IONS, chemistry, copper, Mutation, biology.protein, MC-ICP-MS, multicollector sector field inductively coupled plasma–mass spectrometry, serum
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17246254d5ee9ebbd7fa8a442af2e873Test
http://europepmc.org/articles/PMC7949056Test
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