نتائج البحث

1

Mutant voltage-gated Na+ channels can exert a dominant negative effect through coupled gating

المؤلفون: Isabelle Deschenes, Haiyan Liu, Yang Zheng, Aurore Girardeau, Jérôme Clatot, Céline Marionneau, Kenneth R. Laurita

المساهمون: unité de recherche de l'institut du thorax UMR1087 UMR6291 (ITX), Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), National Institute of Metrology [Beijing], The Johns Hopkins University School of Medicine, Johns Hopkins University (JHU)

المصدر: AJP-Heart and Circulatory Physiology
AJP-Heart and Circulatory Physiology, American Physiological Society, 2018, 315 (5), pp.H1250-h1257. ⟨10.1152/ajpheart.00721.2017⟩

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83e5ef7ff5ba98d43f503501548312c7Test
https://doi.org/10.1152/ajpheart.00721.2017Test

2

Dilated cardiomyopathy mutations in δ-sarcoglycan exert a dominant-negative effect on cardiac myocyte mechanical stability

المؤلفون: Daniel E. Michele, Anoop Gopal, Marc Witcher, Matthew D. Campbell

المصدر: American Journal of Physiology-Heart and Circulatory Physiology. 310:H1140-H1150

مصطلحات موضوعية: Cardiomyopathy, Dilated, musculoskeletal diseases, 0301 basic medicine, congenital, hereditary, and neonatal diseases and abnormalities, medicine.medical_specialty, Cell Membrane Permeability, Glycosylation, Physiology, Mutant, 030105 genetics & heredity, Biology, Transfection, medicine.disease_cause, Mechanotransduction, Cellular, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, Sarcoglycans, Physiology (medical), Internal medicine, medicine, Animals, Humans, Myocyte, Genetic Predisposition to Disease, Myocytes, Cardiac, Cells, Cultured, Genes, Dominant, Mutation, Cell Membrane, Cardiac myocyte, Dilated cardiomyopathy, musculoskeletal system, medicine.disease, Myocardial Contraction, Cell biology, Protein Transport, Sarcoglycan, Phenotype, Endocrinology, chemistry, Call for Papers, Stress, Mechanical, Cardiology and Cardiovascular Medicine, Protein Processing, Post-Translational, Limb-girdle muscular dystrophy

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eb48c2edf1034e2def2b31358625978Test
https://doi.org/10.1152/ajpheart.00521.2015Test

3

20-HETE-induced mitochondrial superoxide production and inflammatory phenotype in vascular smooth muscle is prevented by glucose-6-phosphate dehydrogenase inhibition

المؤلفون: Michael S. Wolin, Katherine H. Gotlinger, Vidhi Dhagia, Anand Lakhkar, Dhara Patel, Sachindra R. Joshi, Michal L. Schwartzman, Dong Sun, Sachin A. Gupte

المصدر: American Journal of Physiology-Heart and Circulatory Physiology. 310:H1107-H1117

مصطلحات موضوعية: Male, 0301 basic medicine, Vascular smooth muscle, Physiology, Anti-Inflammatory Agents, Aorta, Thoracic, 030204 cardiovascular system & hematology, Muscle, Smooth, Vascular, Rats, Sprague-Dawley, Pathogenesis, chemistry.chemical_compound, 0302 clinical medicine, Superoxides, Hydroxyeicosatetraenoic Acids, Enzyme Inhibitors, Extracellular Signal-Regulated MAP Kinases, Superoxide, Phenotype, cardiovascular system, Call for Papers, lipids (amino acids, peptides, and proteins), Tumor necrosis factor alpha, Cytochrome P-450 CYP4A, Inflammation Mediators, Signal transduction, medicine.symptom, Cardiology and Cardiovascular Medicine, Signal Transduction, medicine.medical_specialty, Genotype, Myocytes, Smooth Muscle, Inflammation, Glucosephosphate Dehydrogenase, Pulmonary Artery, Biology, 03 medical and health sciences, Physiology (medical), Internal medicine, Cyclic GMP-Dependent Protein Kinases, medicine, Animals, Glucose-6-phosphate dehydrogenase, ets-Domain Protein Elk-1, Tumor Necrosis Factor-alpha, Molecular biology, Mice, Mutant Strains, Mitochondria, Muscle, MicroRNAs, 030104 developmental biology, Endocrinology, chemistry, Mutation, Cattle, cGMP-dependent protein kinase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f0a068f0d2da325c3593e6352b92773Test
https://doi.org/10.1152/ajpheart.00961.2015Test

4

Heterozygous deletion of sarcolipin maintains normal cardiac function

المؤلفون: Qibin Jiao, Gaku Nakai, Atsushi Nakano, Meihua Jin, Yoshihiro Ishikawa, Daisuke Shimura, Tomohiro Yokota, Yoichiro Kusakari, Nobuhito Goda, Tetsuo Sasano, Susumu Minamisawa, Yasuhiro Nakashima

المصدر: American Journal of Physiology-Heart and Circulatory Physiology. 310:H92-H103

مصطلحات موضوعية: Male, 0301 basic medicine, Heterozygote, medicine.medical_specialty, Genotype, Physiology, Proteolipids, Mutant, Sarcoplasm, Muscle Proteins, Cre recombinase, Endogeny, 030204 cardiovascular system & hematology, Biology, Ventricular Function, Left, Sarcoplasmic Reticulum Calcium-Transporting ATPases, 03 medical and health sciences, 0302 clinical medicine, Physiology (medical), Internal medicine, medicine, Animals, Myocytes, Cardiac, Calcium Signaling, Mice, Knockout, Messenger RNA, Endoplasmic reticulum, Isoproterenol, Gene targeting, Adrenergic beta-Agonists, Fibrosis, Myocardial Contraction, Molecular biology, Mice, Inbred C57BL, Sarcolipin, Sarcoplasmic Reticulum, Phenotype, 030104 developmental biology, Endocrinology, cardiovascular system, Female, Cardiology and Cardiovascular Medicine, Gene Deletion

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f7d447fcb021e94d98be8a3cdeeec54Test
https://doi.org/10.1152/ajpheart.00411.2015Test

5

Rat cardiac troponin T mutation (F72L)-mediated impact on thin filament cooperativity is divergently modulated by α- and β-myosin heavy chain isoforms

المؤلفون: Murali Chandra, Sampath K. Gollapudi, Vikram Chandra

المصدر: American Journal of Physiology-Heart and Circulatory Physiology. 309:H1260-H1270

مصطلحات موضوعية: Cardiomyopathy, Dilated, Male, Gene isoform, genetic structures, Physiology, Mutant, chemical and pharmacologic phenomena, Cooperativity, macromolecular substances, Plasma protein binding, Ventricular Function, Left, Rats, Sprague-Dawley, Myofibrils, Troponin T, Physiology (medical), Myosin, Animals, Genetic Predisposition to Disease, Calcium Signaling, Muscle Strength, Phosphorylation, Actin, Myosin Heavy Chains, Chemistry, Anatomy, Cardiomyopathy, Hypertrophic, Papillary Muscles, musculoskeletal system, Myocardial Contraction, Kinetics, Phenotype, Propylthiouracil, Mutation, Biophysics, Cardiology and Cardiovascular Medicine, Myofibril, Muscle Mechanics and Ventricular Function, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a160a52e1669b49cbc58fcb2e90029f8Test
https://doi.org/10.1152/ajpheart.00519.2015Test

6

Heparan sulfate side chains have a critical role in the inhibitory effects of perlecan on vascular smooth muscle cell response to arterial injury

المؤلفون: Nafiseh Nili, Bradley H. Strauss, Phan Kiet Tran, Richard E. Gilbert, Azriel B. Osherov, Karl Tryggvason, Sang Yup Lim, Suzanne L. Advani, Ya-Ting Chang, Beiping Qiang, Rafael Wolff, Lara Gotha, Karin Tran-Lundmark, Sivaram Pillarisetti, Ilana Erlich, Ulf Hedin

المصدر: American Journal of Physiology-Heart and Circulatory Physiology. 307:H337-H345

مصطلحات موضوعية: Time Factors, Vascular smooth muscle, Genotype, Physiology, Myocytes, Smooth Muscle, Cell, Becaplermin, Mice, Transgenic, Perlecan, Vascular Remodeling, Inhibitory postsynaptic potential, Muscle, Smooth, Vascular, Glycosaminoglycan, Structure-Activity Relationship, chemistry.chemical_compound, Cell Movement, Physiology (medical), Cell Adhesion, medicine, Side chain, Animals, Cells, Cultured, Cell Proliferation, Dose-Response Relationship, Drug, Molecular Structure, biology, Proto-Oncogene Proteins c-sis, Heparan sulfate, Vascular System Injuries, Mice, Mutant Strains, Cell biology, Mice, Inbred C57BL, Disease Models, Animal, Carotid Arteries, Phenotype, medicine.anatomical_structure, Biochemistry, chemistry, Proteoglycan, Mutation, biology.protein, Fibroblast Growth Factor 2, Carotid Artery Injuries, Cardiology and Cardiovascular Medicine, Heparan Sulfate Proteoglycans

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f969376ddf3c7b65479cbe7c7cb9f45aTest
https://doi.org/10.1152/ajpheart.00654.2013Test

7

Contractile dysfunction in a mouse model expressing a heterozygous MYBPC3 mutation associated with hypertrophic cardiomyopathy

المؤلفون: Sakthivel Sadayappan, David Y. Barefield, Mohit Kumar, Pieter P. de Tombe

المصدر: American Journal of Physiology-Heart and Circulatory Physiology. 306:H807-H815

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d919f64621ac2a61c0d1fb839d7a9bd7Test
https://doi.org/10.1152/ajpheart.00913.2013Test

8

Cardiac hypertrophy associated with impaired regulation of cardiac ryanodine receptor by calmodulin and S100A1

المؤلفون: Angela C. Gomez, Daniel A. Pasek, Naohiro Yamaguchi, Gerhard Meissner, Asima Chakraborty, Le Xu, Tai Qin Huang

المصدر: American Journal of Physiology-Heart and Circulatory Physiology. 305:H86-H94

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20240ecef269891eb26ecdf9481d0811Test
https://doi.org/10.1152/ajpheart.00144.2013Test

9

Targets of vascular protection in acute ischemic stroke differ in type 2 diabetes

المؤلفون: Weiguo Li, Susan C. Fagan, Maribeth H. Johnson, Bindu Pillai, Aisha I. Kelly-Cobbs, Adviye Ergul, Safia Ogbi, Sherif Hafez, Roshini Prakash, Maha Coucha

المصدر: American Journal of Physiology-Heart and Circulatory Physiology. 304:H806-H815

مصطلحات موضوعية: Male, medicine.medical_specialty, Curcumin, Metalloporphyrins, Physiology, Vascular Biology and Microcirculation, Ischemia, Hemorrhage, Minocycline, Type 2 diabetes, Matrix Metalloproteinase Inhibitors, Tissue plasminogen activator, Neuroprotection, Rats, Mutant Strains, Peroxynitrous Acid, Physiology (medical), Diabetes mellitus, Internal medicine, Edema, medicine, Animals, Rats, Wistar, Stroke, business.industry, NF-kappa B, Infarction, Middle Cerebral Artery, medicine.disease, Rats, Neuroprotective Agents, Diabetes Mellitus, Type 2, Matrix Metalloproteinase 9, Anesthesia, Cardiology, medicine.symptom, Cardiology and Cardiovascular Medicine, business, Locomotion, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e07c04bdb30374950e5890a9620aabd9Test
https://doi.org/10.1152/ajpheart.00720.2012Test

10

The continuing evolution of the Langendorff and ejecting murine heart: new advances in cardiac phenotyping

المؤلفون: Chee Chew Lim, Bruno K. Podesser, Ronglih Liao

المصدر: American Journal of Physiology-Heart and Circulatory Physiology. 303:H156-H167

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccd04c0d9da035a45599355a55d7165eTest
https://doi.org/10.1152/ajpheart.00333.2012Test

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