نتائج البحث

1

Dilated cardiomyopathy mutations in δ-sarcoglycan exert a dominant-negative effect on cardiac myocyte mechanical stability

المؤلفون: Daniel E. Michele, Anoop Gopal, Marc Witcher, Matthew D. Campbell

المصدر: American Journal of Physiology-Heart and Circulatory Physiology. 310:H1140-H1150

مصطلحات موضوعية: Cardiomyopathy, Dilated, musculoskeletal diseases, 0301 basic medicine, congenital, hereditary, and neonatal diseases and abnormalities, medicine.medical_specialty, Cell Membrane Permeability, Glycosylation, Physiology, Mutant, 030105 genetics & heredity, Biology, Transfection, medicine.disease_cause, Mechanotransduction, Cellular, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, Sarcoglycans, Physiology (medical), Internal medicine, medicine, Animals, Humans, Myocyte, Genetic Predisposition to Disease, Myocytes, Cardiac, Cells, Cultured, Genes, Dominant, Mutation, Cell Membrane, Cardiac myocyte, Dilated cardiomyopathy, musculoskeletal system, medicine.disease, Myocardial Contraction, Cell biology, Protein Transport, Sarcoglycan, Phenotype, Endocrinology, chemistry, Call for Papers, Stress, Mechanical, Cardiology and Cardiovascular Medicine, Protein Processing, Post-Translational, Limb-girdle muscular dystrophy

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eb48c2edf1034e2def2b31358625978Test
https://doi.org/10.1152/ajpheart.00521.2015Test

2

20-HETE-induced mitochondrial superoxide production and inflammatory phenotype in vascular smooth muscle is prevented by glucose-6-phosphate dehydrogenase inhibition

المؤلفون: Michael S. Wolin, Katherine H. Gotlinger, Vidhi Dhagia, Anand Lakhkar, Dhara Patel, Sachindra R. Joshi, Michal L. Schwartzman, Dong Sun, Sachin A. Gupte

المصدر: American Journal of Physiology-Heart and Circulatory Physiology. 310:H1107-H1117

مصطلحات موضوعية: Male, 0301 basic medicine, Vascular smooth muscle, Physiology, Anti-Inflammatory Agents, Aorta, Thoracic, 030204 cardiovascular system & hematology, Muscle, Smooth, Vascular, Rats, Sprague-Dawley, Pathogenesis, chemistry.chemical_compound, 0302 clinical medicine, Superoxides, Hydroxyeicosatetraenoic Acids, Enzyme Inhibitors, Extracellular Signal-Regulated MAP Kinases, Superoxide, Phenotype, cardiovascular system, Call for Papers, lipids (amino acids, peptides, and proteins), Tumor necrosis factor alpha, Cytochrome P-450 CYP4A, Inflammation Mediators, Signal transduction, medicine.symptom, Cardiology and Cardiovascular Medicine, Signal Transduction, medicine.medical_specialty, Genotype, Myocytes, Smooth Muscle, Inflammation, Glucosephosphate Dehydrogenase, Pulmonary Artery, Biology, 03 medical and health sciences, Physiology (medical), Internal medicine, Cyclic GMP-Dependent Protein Kinases, medicine, Animals, Glucose-6-phosphate dehydrogenase, ets-Domain Protein Elk-1, Tumor Necrosis Factor-alpha, Molecular biology, Mice, Mutant Strains, Mitochondria, Muscle, MicroRNAs, 030104 developmental biology, Endocrinology, chemistry, Mutation, Cattle, cGMP-dependent protein kinase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f0a068f0d2da325c3593e6352b92773Test
https://doi.org/10.1152/ajpheart.00961.2015Test

3

Heterozygous deletion of sarcolipin maintains normal cardiac function

المؤلفون: Qibin Jiao, Gaku Nakai, Atsushi Nakano, Meihua Jin, Yoshihiro Ishikawa, Daisuke Shimura, Tomohiro Yokota, Yoichiro Kusakari, Nobuhito Goda, Tetsuo Sasano, Susumu Minamisawa, Yasuhiro Nakashima

المصدر: American Journal of Physiology-Heart and Circulatory Physiology. 310:H92-H103

مصطلحات موضوعية: Male, 0301 basic medicine, Heterozygote, medicine.medical_specialty, Genotype, Physiology, Proteolipids, Mutant, Sarcoplasm, Muscle Proteins, Cre recombinase, Endogeny, 030204 cardiovascular system & hematology, Biology, Ventricular Function, Left, Sarcoplasmic Reticulum Calcium-Transporting ATPases, 03 medical and health sciences, 0302 clinical medicine, Physiology (medical), Internal medicine, medicine, Animals, Myocytes, Cardiac, Calcium Signaling, Mice, Knockout, Messenger RNA, Endoplasmic reticulum, Isoproterenol, Gene targeting, Adrenergic beta-Agonists, Fibrosis, Myocardial Contraction, Molecular biology, Mice, Inbred C57BL, Sarcolipin, Sarcoplasmic Reticulum, Phenotype, 030104 developmental biology, Endocrinology, cardiovascular system, Female, Cardiology and Cardiovascular Medicine, Gene Deletion

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f7d447fcb021e94d98be8a3cdeeec54Test
https://doi.org/10.1152/ajpheart.00411.2015Test

4

Targets of vascular protection in acute ischemic stroke differ in type 2 diabetes

المؤلفون: Weiguo Li, Susan C. Fagan, Maribeth H. Johnson, Bindu Pillai, Aisha I. Kelly-Cobbs, Adviye Ergul, Safia Ogbi, Sherif Hafez, Roshini Prakash, Maha Coucha

المصدر: American Journal of Physiology-Heart and Circulatory Physiology. 304:H806-H815

مصطلحات موضوعية: Male, medicine.medical_specialty, Curcumin, Metalloporphyrins, Physiology, Vascular Biology and Microcirculation, Ischemia, Hemorrhage, Minocycline, Type 2 diabetes, Matrix Metalloproteinase Inhibitors, Tissue plasminogen activator, Neuroprotection, Rats, Mutant Strains, Peroxynitrous Acid, Physiology (medical), Diabetes mellitus, Internal medicine, Edema, medicine, Animals, Rats, Wistar, Stroke, business.industry, NF-kappa B, Infarction, Middle Cerebral Artery, medicine.disease, Rats, Neuroprotective Agents, Diabetes Mellitus, Type 2, Matrix Metalloproteinase 9, Anesthesia, Cardiology, medicine.symptom, Cardiology and Cardiovascular Medicine, business, Locomotion, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e07c04bdb30374950e5890a9620aabd9Test
https://doi.org/10.1152/ajpheart.00720.2012Test

5

Overexpression of angiopoietin-2 impairs myocardial angiogenesis and exacerbates cardiac fibrosis in the diabetic db/db mouse model

المؤلفون: Jian-Xiong Chen, Jeff Reese, Heng Zeng, Judy L. Aschner, Barbara Meyrick

المصدر: American Journal of Physiology-Heart and Circulatory Physiology. 302:H1003-H1012

مصطلحات موضوعية: Male, Vascular Endothelial Growth Factor A, medicine.medical_specialty, Endothelium, Physiology, Angiogenesis, Cardiac fibrosis, Vascular Cell Adhesion Molecule-1, Apoptosis, Biology, Angiopoietin-2, Neovascularization, Mice, chemistry.chemical_compound, Integrative Cardiovascular Physiology and Pathophysiology, Fibrosis, Proto-Oncogene Proteins, Physiology (medical), Internal medicine, Diabetes Mellitus, medicine, Animals, Cells, Cultured, Neovascularization, Pathologic, Caspase 3, Myocardium, Intercellular Adhesion Molecule-1, medicine.disease, Coronary Vessels, Receptor, TIE-2, Mice, Mutant Strains, Up-Regulation, Wnt Proteins, Vascular endothelial growth factor, Disease Models, Animal, Db/db Mouse, Vascular endothelial growth factor A, Endocrinology, medicine.anatomical_structure, chemistry, cardiovascular system, Endothelium, Vascular, medicine.symptom, Cardiology and Cardiovascular Medicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1660cf48d0e5e1b5faeb47632e20f169Test
https://doi.org/10.1152/ajpheart.00866.2011Test

6

Constitutive overexpression of phosphomimetic phospholemman S68E mutant results in arrhythmias, early mortality, and heart failure: potential involvement of Na+/Ca2+ exchanger

المؤلفون: JuFang Wang, Erhe Gao, Xiying Shang, Walter J. Koch, Xue-Qian Zhang, Jianliang Song, Jeffrey I. Joseph, Tung O. Chan, Arthur M. Feldman, Joseph Y. Cheung, Blaise Z. Peterson

المصدر: American Journal of Physiology-Heart and Circulatory Physiology. 302:H770-H781

مصطلحات موضوعية: Male, medicine.medical_specialty, Calcium Channels, L-Type, Physiology, Mutant, Phospholemman, Action Potentials, Gene Expression, chemistry.chemical_element, Mice, Inbred Strains, Mice, Transgenic, Calcium, Biology, Sodium-Calcium Exchanger, Mice, Physiology (medical), Internal medicine, Receptors, Adrenergic, beta, Gene expression, Bradycardia, medicine, Animals, Myocytes, Cardiac, Heart Failure, Sodium-calcium exchanger, Cardiac Excitation and Contraction, Sodium, Membrane Proteins, Arrhythmias, Cardiac, Phosphoproteins, medicine.disease, Myocardial Contraction, Mice transgenic, Cell biology, Endocrinology, Membrane protein, chemistry, Heart failure, Potassium, cardiovascular system, Female, Cardiology and Cardiovascular Medicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8906859e91caf9fd4e07ddd88fbdc2e1Test
https://doi.org/10.1152/ajpheart.00733.2011Test

7

Altered clock gene expression and vascular smooth muscle diurnal contractile variations in type 2 diabeticdb/dbmice

المؤلفون: Jenny Lutshumba, Ming C. Gong, Zhongwen Xie, Wen Su, Marilyn J. Duncan, Zhenheng Guo

المصدر: American Journal of Physiology-Heart and Circulatory Physiology. 302:H621-H633

مصطلحات موضوعية: Male, medicine.medical_specialty, Vascular smooth muscle, Physiology, Vascular Biology and Microcirculation, Gene Expression, Blood Pressure, Biology, Kidney, Muscle, Smooth, Vascular, Mice, Cryptochrome, Physiology (medical), Internal medicine, Gene expression, medicine, Animals, Circadian rhythm, Mesenteric arteries, Aorta, Suprachiasmatic nucleus, Heart, Period Circadian Proteins, Mice, Mutant Strains, Circadian Rhythm, Mesenteric Arteries, Cryptochromes, DNA-Binding Proteins, Mice, Inbred C57BL, PPAR gamma, CLOCK, Endocrinology, medicine.anatomical_structure, Diabetes Mellitus, Type 2, Vasoconstriction, Suprachiasmatic Nucleus, medicine.symptom, Cardiology and Cardiovascular Medicine, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6efcc9382deabdc7cce3534028b87e4Test
https://doi.org/10.1152/ajpheart.00825.2011Test

8

Resveratrol improves left ventricular diastolic relaxation in type 2 diabetes by inhibiting oxidative/nitrative stress: in vivo demonstration with magnetic resonance imaging

المؤلفون: Kevin C. Dellsperger, Barry J. Potter, Cuihua Zhang, Brandon Morgan, Zoltan Zoltan Ungvari, Lixin Ma, Hanrui Zhang

المصدر: American Journal of Physiology-Heart and Circulatory Physiology. 299:H985-H994

مصطلحات موضوعية: Male, medicine.medical_specialty, Nitric Oxide Synthase Type III, Physiology, Diastole, Resveratrol, Nitric Oxide, medicine.disease_cause, Antioxidants, Nitric oxide, Mice, Ventricular Dysfunction, Left, chemistry.chemical_compound, In vivo, Physiology (medical), Internal medicine, Stilbenes, medicine, Animals, Mice, Knockout, chemistry.chemical_classification, Reactive oxygen species, Membrane Glycoproteins, Nitrates, NADPH oxidase, biology, Translational Physiology, Tumor Necrosis Factor-alpha, NF-kappa B, NADPH Oxidases, Magnetic Resonance Imaging, Mice, Mutant Strains, Mice, Inbred C57BL, Oxygen, Disease Models, Animal, Oxidative Stress, Endocrinology, Diabetes Mellitus, Type 2, chemistry, NADPH Oxidase 2, Circulatory system, biology.protein, Female, Reactive Oxygen Species, Cardiology and Cardiovascular Medicine, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7b0e5acf3637c3968f3917bb99b4fd2Test
https://doi.org/10.1152/ajpheart.00489.2010Test

9

Type 1 diabetic cardiomyopathy in the Akita (Ins2WT/C96Y) mouse model is characterized by lipotoxicity and diastolic dysfunction with preserved systolic function

المؤلفون: Xiuhua Wang, Liyang Zhang, Zamaneh Kassiri, Gary D. Lopaschuk, John R. Ussher, Gavin Y. Oudit, Ratnadeep Basu

المصدر: American Journal of Physiology-Heart and Circulatory Physiology. 297:H2096-H2108

مصطلحات موضوعية: Blood Glucose, Male, Heart disease, Physiology, Cardiomyopathy, Mitochondria, Heart, Muscle hypertrophy, Mice, Ventricular Dysfunction, Left, Diastole, Diabetic cardiomyopathy, Natriuretic Peptide, Brain, Insulin, Acyl-CoA Dehydrogenase, Long-Chain, Fatty Acids, Age Factors, Lipotoxicity, Disease Progression, Cardiomyopathies, Cardiology and Cardiovascular Medicine, medicine.medical_specialty, Systole, Protein Serine-Threonine Kinases, Biology, Ceramides, Sarcoplasmic Reticulum Calcium-Transporting ATPases, Diglycerides, Physiology (medical), Internal medicine, Ventricular Pressure, medicine, Animals, Hypoglycemic Agents, Triglycerides, Echocardiography, Doppler, Pulsed, Type 1 diabetes, Myosin Heavy Chains, Myocardium, Pyruvate Dehydrogenase Acetyl-Transferring Kinase, Stroke Volume, Lipid Metabolism, medicine.disease, Myocardial Contraction, Mice, Mutant Strains, Mice, Inbred C57BL, Disease Models, Animal, Diabetes Mellitus, Type 1, Endocrinology, Heart failure

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::222569cd89525538f615f87f8f415ffeTest
https://doi.org/10.1152/ajpheart.00452.2009Test

10

Role of oxidative stress and AT1 receptors in cerebral vascular dysfunction with aging

المؤلفون: Mary L. Modrick, Frank M. Faraci, Sean P. Didion, Curt D. Sigmund

المصدر: American Journal of Physiology-Heart and Circulatory Physiology. 296:H1914-H1919

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b32d5ea132c48ca31a06fdf64514a78cTest
https://doi.org/10.1152/ajpheart.00300.2009Test

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