دورية أكاديمية
Nonequilibrium brain dynamics as a signature of consciousness.
| العنوان: | Nonequilibrium brain dynamics as a signature of consciousness. |
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| المؤلفون: | Sanz Perl, Yonatan, Bocaccio, Hernán, Pallavicini, Carla, Pérez-Ipiña, Ignacio, LAUREYS, Steven, Laufs, Helmut, Kringelbach, Morten, Deco, Gustavo, Tagliazucchi, Enzo |
| المصدر: | Physical Review. E, 104 (1-1), 014411 (2021-07) |
| بيانات النشر: | American Physical Society, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Propofol, Animals, Brain, Unconsciousness, Wakefulness, Consciousness, Brain dynamics, Cognitive functions, Electrocorticography, Entropy production, Functional magnetic resonance imaging, Non equilibrium, Non-human primate, Probability flux, Statistical and Nonlinear Physics, Statistics and Probability, Condensed Matter Physics, Quantitative Biology - Neurons and Cognition, Human health sciences, Neurology, Sciences de la santé humaine, Neurologie |
| الوصف: | The cognitive functions of human and nonhuman primates rely on the dynamic interplay of distributed neural assemblies. As such, it seems unlikely that cognition can be supported by macroscopic brain dynamics at the proximity of equilibrium. We confirmed this hypothesis by investigating electrocorticography data from nonhuman primates undergoing different states of unconsciousness (sleep, and anesthesia with propofol, ketamine, and ketamine plus medetomidine), and functional magnetic resonance imaging data from humans, both during deep sleep and under propofol anesthesia. Systematically, all states of reduced consciousness unfolded at higher proximity to equilibrium compared to conscious wakefulness, as demonstrated by the computation of entropy production and the curl of probability flux in phase space. Our results establish nonequilibrium macroscopic brain dynamics as a robust signature of consciousness, opening the way for the characterization of cognition and awareness using tools from statistical mechanics. |
| نوع الوثيقة: | journal article http://purl.org/coar/resource_type/c_6501Test article peer reviewed |
| اللغة: | English |
| العلاقة: | https://link.aps.org/article/10.1103/PhysRevE.104.014411Test; urn:issn:2470-0045; urn:issn:2470-0053 |
| DOI: | 10.1103/PhysRevE.104.014411 |
| الوصول الحر: | https://orbi.uliege.be/handle/2268/296305Test |
| حقوق: | open access http://purl.org/coar/access_right/c_abf2Test info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsorb.296305 |
| قاعدة البيانات: | ORBi |
| DOI: | 10.1103/PhysRevE.104.014411 |
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