Clinical significance of low creatine phosphokinase values in patients with connective tissue diseases
| العنوان: | Clinical significance of low creatine phosphokinase values in patients with connective tissue diseases |
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| المؤلفون: | Wei, N., Pavlidis, Nicholas, Tsokos, G., Elin, R. J., Plotz, P. H. |
| المساهمون: | Pavlidis, Nicholas [0000-0002-2195-9961] |
| المصدر: | Journal of the American Medical Association |
| بيانات النشر: | American Medical Association (AMA), 1981. |
| سنة النشر: | 1981 |
| مصطلحات موضوعية: | Adult, Male, Connective tissue diseases, Lupus erythematosus, Myositis, Arthritis, Muscles, Systemic, Major clinical study, General Medicine, Reference values, Systemic lupus erythematosus, Human cell, Sjogren's syndrome, Rheumatoid, Humans, Female, Creatine kinase, Rheumatoid arthritis, Ligament, Sjoegren syndrome |
| الوصف: | We have noted that values for serum creatine phosphokinase (CPK) are frequently low in patients with connective tissue diseases. Geometric mean values were 96.0 units/L among 121 disease-free males and 50.2 units/L among 63 disease-free females. The geometric mean values were 31.7 units/L in 11 males and 35.2 units/L in 49 females with systemic lupus erythematosus; 15.1 units/L in three males and 13.0 units/L in ten females with rheumatoid arthritis; and 41.6 units/L in 19 females with Sjogren's syndrome. Values within the normal range may occur in the face of active myositis in these illnesses. Findings of a low serum CPK value may occur in the absence of steroid treatment. Thus, a low serum CPK value is frequently found in patients with connective tissue disease and a normal value should not dissuade one from the diagnosis of myositis. 246 17 1921 1923 |
| تدمد: | 1538-3598 0098-7484 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::627424b29fc412a9a2b539c3f731a438Test https://doi.org/10.1001/jama.246.17.1921Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....627424b29fc412a9a2b539c3f731a438 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15383598 00987484 |
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