Dietary fiber intake and risk of colorectal cancer: a pooled analysis of prospective cohort studies
| العنوان: | Dietary fiber intake and risk of colorectal cancer: a pooled analysis of prospective cohort studies |
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| المؤلفون: | Vittorio Krogh, Piet A. van den Brandt, Stephanie A. Smith-Warner, Ikuko Kato, David R. Jacobs, Anthony B. Miller, Walter C. Willett, David J. Hunter, Anne Zeleniuch-Jacquotte, Jo L. Freudenheim, Leif Bergkvist, Pirjo Pietinen, Franco Berrino, Shumin M. Zhang, Donna Spiegelman, Charles S. Fuchs, Julie E. Buring, Michael F. Leitzmann, R. Alexandra Goldbohm, Marjorie L. McCullough, Thomas E. Rohan, Arthur Schatzkin, Lisa J. Harnack, Graham A. Colditz, Saxon Graham, Edward Giovannucci, Anne M. Hartman, Yikyung Park, Alicja Wolk |
| المساهمون: | Epidemiologie, RS: NUTRIM School of Nutrition and Translational Research in Metabolism, RS: CAPHRI School for Public Health and Primary Care, TNO Kwaliteit van Leven |
| المصدر: | Journal of the American Medical Association, 22, 294, 2849-2857 JAMA-Journal of the American Medical Association, 294, 2849-2857. American Medical Association |
| بيانات النشر: | American Medical Association, 2005. |
| سنة النشر: | 2005 |
| مصطلحات موضوعية: | Dietary Fiber, Male, Risk, medicine.medical_specialty, cancer incidence, Colorectal cancer, Food and Chemical Risk Analysis, Context (language use), Diet and cancer, colorectal carcinoma, Internal medicine, medicine, follow up, Humans, controlled study, human, Risk factor, Prospective cohort study, Proportional Hazards Models, evaluation, business.industry, adult, disease association, article, risk assessment, General Medicine, sex ratio, medicine.disease, major clinical study, Surgery, female, multivariate analysis, priority journal, risk factor, Health, Relative risk, Population study, business, dietary intake, Colorectal Neoplasms, Cohort study, prospective study |
| الوصف: | Context: Inconsistent findings from observational studies have continued the controversy over the effects of dietary fiber on colorectal cancer. Objective: To evaluate the association between dietary fiber intake and risk of colorectal cancer. Design, Setting, and Participants: From 13 prospective cohort studies included in the Pooling Project of Prospective Studies of Diet and Cancer, 725 628 men and women were followed up for 6 to 20 years across studies. Study- and sex-specific relative risks (RRs) were estimated with the Cox proportional hazards model and were subsequently pooled using a random-effects model. Main Outcome Measure: Incident colorectal cancer. Results: During 6 to 20 years of follow-up across studies, 8081 colorectal cancer cases were identified. For comparison of the highest vs lowest study- and sex-specific quintile of dietary fiber intake, a significant inverse association was found in the age-adjusted model (pooled RR=0.84; 95% confidence interval [CI], 0.77-0.92). However, the association was attenuated and no longer statistically significant after adjusting for other risk factors (pooled multivariate RR=0.94; 95% CI, 0.86-1.03). In categorical analyses compared with dietary fiber intake of 10 to |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1538-3598 0098-7484 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a72ad31abb48a2ce21be3afbe970999bTest https://cris.maastrichtuniversity.nl/en/publications/6a477b16-6332-4493-bda1-4284e089e9b1Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....a72ad31abb48a2ce21be3afbe970999b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15383598 00987484 |
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