Efficacy of Artificial Pancreas Use in Patients With Type 2 Diabetes Using Intensive Insulin Therapy: A Randomized Crossover Pilot Trial
| العنوان: | Efficacy of Artificial Pancreas Use in Patients With Type 2 Diabetes Using Intensive Insulin Therapy: A Randomized Crossover Pilot Trial |
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| المؤلفون: | Virginie Messier, André C. Carpentier, Nadine Taleb, Rémi Rabasa-Lhoret, Martin Ladouceur, Ahmad Haidar |
| المصدر: | Diabetes Care. 42:e107-e109 |
| بيانات النشر: | American Diabetes Association, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Advanced and Specialized Nursing, medicine.medical_specialty, Type 1 diabetes, Evening, business.industry, Endocrinology, Diabetes and Metabolism, Insulin, medicine.medical_treatment, 030209 endocrinology & metabolism, Type 2 diabetes, medicine.disease, Crossover study, Artificial pancreas, 03 medical and health sciences, 0302 clinical medicine, Bolus (medicine), Diabetes mellitus, Internal medicine, Internal Medicine, medicine, 030212 general & internal medicine, business |
| الوصف: | Artificial pancreas (AP) systems have proven efficacy and superiority in glucose control compared with other insulin delivery methods in patients with type 1 diabetes (1,2). Patients with type 2 diabetes (T2D) requiring intensive insulin therapy are difficult to treat and could potentially benefit from AP. Two published reports have addressed AP and T2D in hospitalized patients, with overall results favoring AP (2,3). We aimed to test the applicability of a single-hormone (SH) (insulin only) AP algorithm in patients with T2D who require multiple daily injections (MDI) of insulin. We conducted an open-label, randomized, crossover study to compare glucose control under SH-AP and MDI in adults with T2D (≥55 years old, BMI >25 kg/m2, on ≥3 insulin injections/day). Exclusion criteria were change in hypoglycemic agents within 6 weeks prior to or during the study, creatinine clearance |
| تدمد: | 1935-5548 0149-5992 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f72756ad23c82f17fa3b4e245b64d9c2Test https://doi.org/10.2337/dc18-2406Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....f72756ad23c82f17fa3b4e245b64d9c2 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19355548 01495992 |
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