دورية أكاديمية

Associations of Four Community Factors With Longitudinal Change in Hemoglobin A1c Levels in Patients With Type 2 Diabetes.

التفاصيل البيبلوغرافية
العنوان: Associations of Four Community Factors With Longitudinal Change in Hemoglobin A1c Levels in Patients With Type 2 Diabetes.
المؤلفون: Hirsch, Annemarie G.1,2 aghirsch@geisinger.edu, Durden, T. Elizabeth3, Nordberg, Cara4, Berger, Andrea4, Schwartz, Brian S.1,2
المصدر: Diabetes Care. Mar2018, Vol. 41 Issue 3, p461-468. 8p.
مصطلحات موضوعية: *TYPE 2 diabetes, *GLYCOSYLATED hemoglobin, *PEOPLE with diabetes, *PHYSICAL activity, *TREATMENT of diabetes
مستخلص: Objective: To evaluate associations of community factors with glycated hemoglobin (HbA1c).Research Design and Methods: We identified patients with type 2 diabetes who had an HbA1c ≥7.5% (58 mmol/mol) and subsequent HbA1c testing within 90-270 days. We used mixed-effect models to assess whether treatment intensification (TI) and community domains (community socioeconomic deprivation [CSD], food availability, fitness assets, and utilitarian physical activity favorability [quartiled]) were associated with HbA1c change over 6 and 24 months, controlling for demographics, HbA1c, BMI, and time with evidence of type 2 diabetes. We evaluated whether community domains modified associations of TI with HbA1c change using cross product terms.Results: There were 15,308 patients with 69,818 elevated HbA1c measures. The average reduction in HbA1c over 6 months was 0.07% less in townships with a high level of CSD (third quartile versus the first). Reductions were 0.10% greater for HbA1c in townships with the best food availability (versus worst). HbA1c reductions were 0.17-0.19% greater in census tracts in the second and third quartiles of utilitarian physical activity favorability versus the first. The association of TI with 6-month HbA1c change was weaker in townships and boroughs with the worst CSD (versus best) and in boroughs with the best fitness assets (versus worst). The association of TI with 24-month HbA1c change was weaker in census tracts with the worst CSD (versus third quartile) and strongest in census tracts most favorable for utilitarian physical activity (versus worst).Conclusions: Community domains were associated with HbA1c change and blunted TI effectiveness. [ABSTRACT FROM AUTHOR]
قاعدة البيانات: Academic Search Index
الوصف
تدمد:01495992
DOI:10.2337/dc17-1200