التفاصيل البيبلوغرافية
| العنوان: |
One-Year Outcome of Critically Ill Patients With Systemic Rheumatic Disease: A Multicenter Cohort Study. |
| المؤلفون: |
Larcher, Romaric, Pineton de Chambrun, Marc, Garnier, Fanny, Rubenstein, Emma, Carr, Julie, Charbit, Jonathan, Chalard, Kevin, Mourad, Marc, Amalric, Matthieu, Platon, Laura, Brunot, Vincent, Amoura, Zahir, Jaber, Samir, Jung, Boris, Luyt, Charles-Edouard, Klouche, Kada |
| المصدر: |
CHEST; Sep2020, Vol. 158 Issue 3, p1017-1026, 10p |
| مصطلحات موضوعية: |
RHEUMATISM, CRITICALLY ill, HOSPITAL mortality, ADULT respiratory distress syndrome, MEDICAL records, RHEUMATISM treatment, INTENSIVE care units, LENGTH of stay in hospitals, THERAPEUTICS, RESEARCH, ADRENOCORTICAL hormones, AGE distribution, RESEARCH methodology, RENAL replacement therapy, APACHE (Disease classification system), HEALTH status indicators, RETROSPECTIVE studies, MEDICAL cooperation, EVALUATION research, CATASTROPHIC illness, ARTIFICIAL respiration, COMPARATIVE studies, PSYCHOLOGICAL tests, PATIENT-family relations |
| مصطلحات جغرافية: |
FRANCE |
| مستخلص: |
Background: Critically ill patients with systemic rheumatic disease (SRD) have benefited from better provision of rheumatic and critical care in recent years. Recent comprehensive data regarding in-hospital mortality rates and, most importantly, long-term outcomes are scarce.Research Question: The aim of this study was to assess short and long-term outcome of patients with SRD who were admitted to the ICU.Study Design and Methods: All records of patients with SRD who were admitted to ICU between 2006 and 2016 were reviewed. In-hospital and one-year mortality rates were assessed, and predictive factors of death were identified.Results: A total of 525 patients with SRD were included. Causes of admission were most frequently shock (40.8%) and acute respiratory failure (31.8%). Main diagnoses were infection (39%) and SRD flare-up (35%). In-hospital and one-year mortality rates were 30.5% and 37.7%, respectively. Predictive factors that were associated with in-hospital and one-year mortalities were, respectively, age, prior corticosteroid therapy, simplified acute physiology score II ≥50, need for invasive mechanical ventilation, or need for renal replacement therapy. Knaus scale C or D and prior conventional disease modifying antirheumatic drug therapy was associated independently with death one-year after ICU admission.Interpretation: Critically ill patients with SRD had a fair outcome after an ICU stay. Increased age, prior corticosteroid therapy, and severity of critical illness were associated significantly with short- and long-term mortality rates. The one-year mortality rate was also associated with prior health status and conventional disease modifying antirheumatic drug therapy. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
