Long-Term Benefit of Early Pre-Reperfusion Metoprolol Administration in Patients With Acute Myocardial Infarction Results From the METOCARD-CNIC Trial (Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction)
| العنوان: | Long-Term Benefit of Early Pre-Reperfusion Metoprolol Administration in Patients With Acute Myocardial Infarction Results From the METOCARD-CNIC Trial (Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction) |
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| المؤلفون: | Pizarro, Gonzalo, Fernández-Friera, Leticia, Fuster, Valentin, Fernández-Jiménez, Rodrigo, García-Ruiz, José M., García-Álvarez, Ana, Mateos, Alonso, Barreiro, María V., Escalera, Noemí, Rodriguez, Maite D., de Miguel, Antonio, García-Lunar, Inés, Parra-Fuertes, Juan J., Sánchez-González, Javier, Pardillos, Luis, Nieto, Beatriz, Jiménez, Adriana, Abejón, Raquel, Bastante, Teresa, Martínez de Vega, Vicente, Cabrera, José A., López-Melgar, Beatriz, Guzman, Gabriela, García-Prieto, Jaime, Mirelis, Jesús G., Zamorano, José Luis, Albarrán, Agustín, Goicolea, Javier, Escaned, Javier, Pocock, Stuart, Iñiguez, Andrés, Fernández-Ortiz, Antonio, Sánchez-Brunete, Vicente, Macaya, Carlos, Ibanez, Borja |
| المصدر: | Journal of the American College of Cardiology. (22):2356-2362 |
| بيانات النشر: | American College of Cardiology Foundation. Published by Elsevier Inc. |
| مصطلحات موضوعية: | STEMI, LVEF, myocardial infarction, ICD, heart failure, magnetic resonance imaging, PCI, cardiovascular diseases, infarct size, metoprolol, beta-adrenergic receptors |
| الوصف: | ObjectivesThe goal of this trial was to study the long-term effects of intravenous (IV) metoprolol administration before reperfusion on left ventricular (LV) function and clinical events.BackgroundEarly IV metoprolol during ST-segment elevation myocardial infarction (STEMI) has been shown to reduce infarct size when used in conjunction with primary percutaneous coronary intervention (pPCI).MethodsThe METOCARD-CNIC (Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction) trial recruited 270 patients with Killip class ≤II anterior STEMI presenting early after symptom onset ( |
| اللغة: | English |
| تدمد: | 0735-1097 0131-1700 |
| DOI: | 10.1016/j.jacc.2014.03.014 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::ae8984c12af1ce52be04486135446517Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.core.ac.uk....ae8984c12af1ce52be04486135446517 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 07351097 01311700 |
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| DOI: | 10.1016/j.jacc.2014.03.014 |