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1
المؤلفون: Sophia D. Staerz, Erika M. Lisabeth, Evert Njomen, Thomas S. Dexheimer, Richard R. Neubig, Jetze J. Tepe
المصدر: ACS Omega. 8:15650-15659
مصطلحات موضوعية: General Chemical Engineering, General Chemistry
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::68594d4b374e3503ad634e530ac8d11eTest
https://doi.org/10.1021/acsomega.3c01158Test -
2
المؤلفون: Dinesh Khanna, Duxin Sun, Marc Bailie, Thomas S. Dexheimer, Richard R. Neubig, Bo Wen, Jeffrey R. Leipprandt, Scott D. Larsen, Pei-Suen Tsou, Andrew J. Haak, Kim Hutchings, Erika M. Lisabeth, Phillip L. Campbell, Dylan Kahl, David A. Fox
المصدر: Journal of Medicinal Chemistry. 62:4350-4369
مصطلحات موضوعية: rho GTP-Binding Proteins, Serum Response Factor, Transcription, Genetic, Carboxylic Acids, 01 natural sciences, Article, Scleroderma, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Drug Discovery, Serum response factor, medicine, Animals, Luciferase, Enzyme Inhibitors, Transcription factor, Skin, 030304 developmental biology, Oxadiazoles, 0303 health sciences, Scleroderma, Systemic, Molecular Structure, Aryl, Connective Tissue Growth Factor, medicine.disease, Serum Response Element, Fibrosis, Phenotype, 0104 chemical sciences, Mice, Inbred C57BL, 010404 medicinal & biomolecular chemistry, chemistry, Myocardin, Microsomes, Liver, Trans-Activators, Cancer research, Molecular Medicine, Female, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dde3f247ab6ce076613b75c660a77076Test
https://doi.org/10.1021/acs.jmedchem.8b01772Test -
3
المؤلفون: Erika M. Lisabeth, Dylan Kahl, Indiwari Gopallawa, Sarah E. Haynes, Sean A. Misek, Phillip L. Campbell, Thomas S. Dexheimer, Dinesh Khanna, David A. Fox, Xiangshu Jin, Brent R. Martin, Scott D. Larsen, Richard R. Neubig
المصدر: ACS Pharmacology & Translational Science. 2:92-100
مصطلحات موضوعية: Pharmacology, Pharmacology (medical), Article
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e04156d0c2d45fc9015adba97c002ebTest
https://doi.org/10.1021/acsptsci.8b00048Test -
4
المصدر: Journal of the American Chemical Society. 140:3454-3460
مصطلحات موضوعية: 0301 basic medicine, Protein Conformation, G protein, GTPase, Molecular Dynamics Simulation, Biochemistry, Article, Catalysis, Small Molecule Libraries, RGS4, 03 medical and health sciences, 0302 clinical medicine, Colloid and Surface Chemistry, Thiadiazoles, Animals, Humans, Protein Interaction Maps, Receptor, G protein-coupled receptor, biology, Chemistry, fungi, General Chemistry, Small molecule, 030104 developmental biology, biology.protein, sense organs, RGS Proteins, 030217 neurology & neurosurgery, Signal Transduction, Cysteine
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfe712f1bc56a3d9e320d892f38c8520Test
https://doi.org/10.1021/jacs.7b13778Test -
5
المصدر: ACS Chemical Biology. 8:2778-2784
مصطلحات موضوعية: G protein, Allosteric regulation, Molecular Dynamics Simulation, Biochemistry, Article, Protein Structure, Secondary, Small Molecule Libraries, Protein structure, Regulator of G protein signaling, Allosteric Regulation, Heterotrimeric G protein, Humans, Cysteine, biology, Chemistry, General Medicine, Small molecule, Protein Structure, Tertiary, Molecular Docking Simulation, Kinetics, Allosteric enzyme, biology.protein, Biophysics, Molecular Medicine, Thiazolidinediones, RGS Proteins, Allosteric Site, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f730f66fa42a89ea19b34579ce54bbdcTest
https://doi.org/10.1021/cb400568gTest -
6
المصدر: Biochemistry. 50:3181-3192
مصطلحات موضوعية: Models, Molecular, Alkylation, GTPase-activating protein, Cell Survival, Protein Conformation, Regulatory site, GTP-Binding Protein alpha Subunits, Gi-Go, Biology, Biochemistry, Article, Substrate Specificity, chemistry.chemical_compound, Thiadiazoles, Humans, Cysteine, Cysteine metabolism, RGS2, fungi, Flow Cytometry, RGS17, HEK293 Cells, chemistry, Biocatalysis, Iodoacetamide, Thiazolidinediones, RGS Proteins
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e1a3048c5c89a976b1dcbc86838e7e0Test
https://doi.org/10.1021/bi1019622Test -
7
المؤلفون: John F. Dishinger, Chetwana Rungwanitcha, David L. Roman, Robert T. Kennedy, Jian Pei, Richard R. Neubig
المصدر: Analytical Chemistry. 80:5225-5231
مصطلحات موضوعية: Boron Compounds, Analyte, Microfluidics, Drug Evaluation, Preclinical, Guanosine Diphosphate, Michaelis–Menten kinetics, Article, Fluorescence spectroscopy, GTP Phosphohydrolases, Analytical Chemistry, GTP-Binding Proteins, Chromatography, Dose-Response Relationship, Drug, biology, Rhodamines, Chemistry, Hydrolysis, Electrophoresis, Capillary, Substrate (chemistry), Microfluidic Analytical Techniques, Chip, Enzyme assay, Kinetics, Electrophoresis, Guanosine 5'-O-(3-Thiotriphosphate), biology.protein, Guanosine Triphosphate, RGS Proteins
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d6d20862e562b19ea93616c1bc5ac65Test
https://doi.org/10.1021/ac800553gTest -
8
المؤلفون: Graeme Milligan, Susan M. Wade, Robert T. Kennedy, Jian Pei, Emily E. Jameson, Richard R. Neubig
المصدر: Analytical Chemistry. 79:1158-1163
مصطلحات موضوعية: GTP', G protein, Chemistry, Cell Membrane, Drug Evaluation, Preclinical, Fluorescence spectrometry, Electrophoresis, Capillary, GTPase, Ligands, Transfection, Guanosine Diphosphate, Fusion protein, Cell Line, GTP Phosphohydrolases, Receptors, G-Protein-Coupled, Analytical Chemistry, Regulator of G protein signaling, Capillary electrophoresis, Biochemistry, Receptors, Adrenergic, alpha-2, Humans, Guanosine Triphosphate, Fluorescent Dyes, G protein-coupled receptor
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39577823a84f3cf3dc9290e8e632b066Test
https://doi.org/10.1021/ac061099gTest -
9
المؤلفون: Richard A. Goldstein, Dimmic Matt W, Orkun S. Soyer, Richard R. Neubig
المصدر: Biochemistry. 42:14522-14531
مصطلحات موضوعية: Models, Molecular, Sequence analysis, Context (language use), Computational biology, Biochemistry, Receptors, G-Protein-Coupled, Evolution, Molecular, Receptors, Biogenic Amine, Sequence Analysis, Protein, Animals, Humans, Binding site, Protein secondary structure, Probability, G protein-coupled receptor, Models, Statistical, biology, Mechanism (biology), Computational Biology, Transmembrane protein, Amino Acid Substitution, Models, Chemical, Rhodopsin, Multigene Family, biology.protein, Dimerization
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a05b8abba967dcee9cb884db3ae1c0bTest
https://doi.org/10.1021/bi035097rTest -
10
المؤلفون: Roger K. Sunahara, Richard R. Neubig, Robert T. Kennedy, Jennifer M. Cunliffe, Emily E. Jameson
المصدر: Analytical Chemistry. 75:4297-4304
مصطلحات موضوعية: Tris, Detection limit, Chromatography, GTP', G protein, Temperature, Electrophoresis, Capillary, GTP-Binding Protein alpha Subunits, Analytical Chemistry, Proto-Oncogene Proteins p21(ras), Dissociation constant, Kinetics, Electrophoresis, chemistry.chemical_compound, Capillary electrophoresis, chemistry, GTP-Binding Proteins, Animals, Guanosine Triphosphate, BODIPY, Fluorescent Dyes
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db9ab086e0471f2d6c85f98bf54e5c2aTest
https://doi.org/10.1021/ac0342976Test