المؤلفون: Xin, Han, Zhao, Lijie, Xiang, Weiguo, Qin, Chong, Miao, Bukeyan, Xu, Tianfeng, Wang, Mi, Yang, Chao-Yie, Chinnaswamy, Krishnapriya, Stuckey, Jeanne, Wang, Shaomeng

مصطلحات موضوعية: Androgen Receptor Antagonists, Cell Proliferation, Drug Design, Drug Discovery, Humans, Ligands, Male, Piperidines, Prostatic Neoplasms, Proteasome Endopeptidase Complex, Proteolysis, Receptors, Androgen, Small Molecule Libraries, Tumor Cells, Cultured, Ubiquitin, Ubiquitin-Protein Ligases, Von Hippel-Lindau Tumor Suppressor Protein

جغرافية الموضوع: United States

وصف الملف: Print-Electronic; application/pdf

العلاقة: https://www.ncbi.nlm.nih.gov/pubmed/31804827Test; https://hdl.handle.net/2027.42/192132Test; https://dx.doi.org/10.7302/22132Test; Journal of Medicinal Chemistry; orcid:0000-0002-5908-4072; orcid:0000-0002-4192-8900; orcid:0000-0002-8782-6950; 62; 24; 11218; 11231; Xin, Han; Zhao, Lijie; Xiang, Weiguo; Qin, Chong; Miao, Bukeyan; Xu, Tianfeng; Wang, Mi; 0000-0002-5908-4072; Yang, Chao-Yie; Chinnaswamy, Krishnapriya; Stuckey, Jeanne; 0000-0002-4192-8900; Wang, Shaomeng; 0000-0002-8782-6950

الإتاحة: https://doi.org/10.1021/acs.jmedchem.9b01393Test
https://doi.org/10.7302/22132Test
https://hdl.handle.net/2027.42/192132Test
https://www.ncbi.nlm.nih.gov/pubmed/31804827Test

المؤلفون: Trapotsi, Maria-Anna, Mouchet, Elizabeth, Williams, Guy, Monteverde, Tiziana, Juhani, Karolina, Turkki, Riku, Miljković, Filip, Martinsson, Anton, Mervin, Lewis, Pryde, Kenneth R, Müllers, Erik, Barrett, Ian, Engkvist, Ola, Bender, Andreas, Moreau, Kevin

المصدر: essn: 1554-8937 ; nlmid: 101282906

مصطلحات موضوعية: Humans, High-Throughput Screening Assays, Proteasome Endopeptidase Complex, Proteolysis, Ubiquitin-Protein Ligases

وصف الملف: application/pdf

العلاقة: https://www.repository.cam.ac.uk/handle/1810/339915Test

الإتاحة: https://doi.org/10.17863/CAM.87338Test
https://www.repository.cam.ac.uk/handle/1810/339915Test

المؤلفون: Xinyi Wu, Ping Sun, Xiuhui Chen, Lei Hua, Haowei Cai, Zhuorong Liu, Cheng Zhang, Shuli Liang, Yanhong Chen, Dan Wu, Yitao Ou, Wenhui Hu, Zhongjin Yang

المصدر: Journal of Medicinal Chemistry. 65:11985-12001

مصطلحات موضوعية: Mice, Inbred C57BL, Mice, Proteasome Endopeptidase Complex, Inflammasomes, Interleukin-1beta, NLR Family, Pyrin Domain-Containing 3 Protein, Drug Discovery, Anti-Inflammatory Agents, Animals, Molecular Medicine, Proteasome Inhibitors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aab8a2f7ce644c8aa45e667a1041b10fTest
https://doi.org/10.1021/acs.jmedchem.2c00523Test

المؤلفون: Lan Huang, Wenxue Li, Yansheng Liu, Clinton Yu, Xiaorong Wang

المصدر: Anal Chem
Analytical chemistry, vol 93, iss 39

مصطلحات موضوعية: Proteomics, Proteasome Endopeptidase Complex, Chemistry, Extramural, Computational biology, Core Particle, Article, Analytical Chemistry, Proteasome, Affinity chromatography, 19S regulatory particle, Proteasome endopeptidase complex, Generic health relevance, Other Chemical Sciences

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::180ab5d4559f26aa0f1c13695c889a55Test
https://doi.org/10.1021/acs.analchem.1c03551Test

المؤلفون: Zhen Dai, Lu-yan An, Xiao-yi Chen, Fan Yang, Ni Zhao, Cui-cui Li, Ren Ren, Bing-yan Li, Wei-yan Tao, Pei Li, Cheng Jiang, Fang Yan, Zheng-yu Jiang, Qi-dong You, Bin Di, Li-li Xu

المصدر: Journal of Medicinal Chemistry. 65:5029-5043

مصطلحات موضوعية: Oxadiazoles, Oxidative Stress, Proteasome Endopeptidase Complex, NF-E2-Related Factor 2, Drug Discovery, Hunting, Molecular Medicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6a868bdc79e37c4cc3ee514246faec3Test
https://doi.org/10.1021/acs.jmedchem.1c02210Test

المؤلفون: Xufen Yu, Jia Xu, Yudao Shen, Kaitlyn M. Cahuzac, Kwang-su Park, Brandon Dale, Jing Liu, Ramon E. Parsons, Jian Jin

المصدر: J Med Chem

مصطلحات موضوعية: Male, Proteasome Endopeptidase Complex, Dose-Response Relationship, Drug, Ubiquitin, Biological Availability, Mice, Nude, Antineoplastic Agents, Xenograft Model Antitumor Assays, Article, Mice, Structure-Activity Relationship, Pyrimidines, Cell Line, Tumor, PC-3 Cells, Proteolysis, Drug Discovery, Animals, Humans, Molecular Medicine, Pyrroles, Protein Kinase Inhibitors, Proto-Oncogene Proteins c-akt, Cell Division, Tumor Stem Cell Assay

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::339785175c1d33f70c781f6819c2f890Test
https://doi.org/10.1021/acs.jmedchem.1c02165Test

المؤلفون: Jibu Lu, Yongjun Huang, Jing Huang, Rui He, Minhao Huang, Xiaoyun Lu, Yong Xu, Fengtao Zhou, Zhang Zhang, Ke Ding

المصدر: Journal of Medicinal Chemistry. 65:2313-2328

مصطلحات موضوعية: Male, Proteasome Endopeptidase Complex, Transplantation, Heterologous, Mice, SCID, Protein-Tyrosine Kinases, Ligands, Mice, Structure-Activity Relationship, Von Hippel-Lindau Tumor Suppressor Protein, Cell Line, Tumor, Drug Design, Neoplasms, Proteolysis, Drug Discovery, Animals, Humans, Molecular Medicine, Protein Kinase Inhibitors, Cell Proliferation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ea1215ad315f59529f85ec1249b81aaTest
https://doi.org/10.1021/acs.jmedchem.1c01768Test

المؤلفون: Xuechun Li, Ming Li, Chen Li, Guang Yang, Ning Liu, Ruonan Wang, Cheng Yang, Sheng Cao, Lan Ma, Yulin Liu, Zhiqiang Dong, Xiaoji Wang, Yuhong Yao, Mingming Wei

المصدر: Journal of Medicinal Chemistry. 64:16497-16511

مصطلحات موضوعية: Proteasome Endopeptidase Complex, Antineoplastic Agents, Apoptosis, Drug resistance, Quinolones, medicine.disease_cause, Structure-Activity Relationship, In vivo, Cell Line, Tumor, hemic and lymphatic diseases, Drug Discovery, medicine, Humans, Cell Proliferation, Mutation, Ubiquitin, Chemistry, Proteolysis targeting chimera, Myeloid leukemia, hemic and immune systems, In vitro, body regions, Leukemia, Myeloid, Acute, fms-Like Tyrosine Kinase 3, Proteolysis, embryonic structures, Cancer research, Molecular Medicine, Benzimidazoles, Antiproliferative effect, Reactive Oxygen Species, psychological phenomena and processes, Signal Transduction, Flt3 itd

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22bc3c0ff7344688035716e00fe57921Test
https://doi.org/10.1021/acs.jmedchem.1c00996Test

المؤلفون: Maria-Anna Trapotsi, Elizabeth Mouchet, Guy Williams, Tiziana Monteverde, Karolina Juhani, Riku Turkki, Filip Miljković, Anton Martinsson, Lewis Mervin, Kenneth R. Pryde, Erik Müllers, Ian Barrett, Ola Engkvist, Andreas Bender, Kevin Moreau

المساهمون: Miljković, Filip [0000-0001-5365-505X], Mervin, Lewis [0000-0002-7271-0824], Engkvist, Ola [0000-0003-4970-6461], Bender, Andreas [0000-0002-6683-7546], Moreau, Kevin [0000-0002-3688-3998], Apollo - University of Cambridge Repository

مصطلحات موضوعية: Proteasome Endopeptidase Complex, Ubiquitin-Protein Ligases, Proteolysis, Molecular Medicine, Humans, General Medicine, Biochemistry, High-Throughput Screening Assays

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4d888b3f3a2dcac91d7eedf99b7082cTest

المؤلفون: Felix Rohdich, Stefano Crosignani, Michael Busch, Christina Esdar, Manja Friese-Hamim, Markus Klein, Thomas Fuchss, Oliver Schadt, Djordje Musil, Ugo Zanelli, Michael P. Sanderson, Gina Walter-Bausch, Philip Hewitt, Jeyaprakashnarayanan Seenisamy

المصدر: Journal of Medicinal Chemistry. 64:10230-10245

مصطلحات موضوعية: Gene isoform, Proteasome Endopeptidase Complex, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Protein subunit, Protein degradation, medicine.disease, Protein Subunits, Structure-Activity Relationship, Haematopoiesis, Proteasome, Biochemistry, Drug Discovery, medicine, Humans, Molecular Medicine, Potency, Structure based, Proteasome Inhibitors, Multiple myeloma

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1a3d051fc60306aef1b64a7ba1b3e7bTest
https://doi.org/10.1021/acs.jmedchem.1c00604Test