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المؤلفون: Anne E. Fitzgerald, Tatiana Koudriakova, Kevin J. Coe, Anthony Ndifor, Cathy Preville, Christine Dugovic, Neelakandha S. Mani, Nicholas I. Carruthers, Michele C. Rizzolio, Timothy W. Lovenberg, Brock T. Shireman, Diane Nepomuceno, Coate Heather R, Daniel J. Pippel, Brian Lord, Allison Brett Douglas, Curt A. Dvorak, Pascal Bonaventure
المصدر: ACS Med Chem Lett
مصطلحات موضوعية: 010405 organic chemistry, Chemistry, Sleep wake, digestive, oral, and skin physiology, Organic Chemistry, Antagonist, Neuropeptide, Pharmacology, 01 natural sciences, Biochemistry, Orexin receptor, 0104 chemical sciences, Orexin, 010404 medicinal & biomolecular chemistry, nervous system, mental disorders, Drug Discovery, Receptor, Mode of action, hormones, hormone substitutes, and hormone antagonists, psychological phenomena and processes
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b157e2b40c4b8187c17e0918f6f2afcTest
https://doi.org/10.1021/acsmedchemlett.0c00085Test -
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المؤلفون: Hideaki Fujii, Yasuhiro Ogawa, Hiroshi Nagase, Noriki Kutsumura, Tsuyoshi Saitoh, Daisuke Kuroda, Takashi Nagahara, Hidetoshi Kumagai, Yoko Irukayama-Tomobe, Masashi Yanagisawa, Hiroaki Gouda
المصدر: Journal of Medicinal Chemistry. 58:7931-7937
مصطلحات موضوعية: Models, Molecular, Agonist, medicine.medical_specialty, Cataplexy, medicine.drug_class, Neuropeptide, CHO Cells, Pharmacology, Small Molecule Libraries, Structure-Activity Relationship, Cricetulus, X-Ray Diffraction, Orexin Receptors, Cell Line, Tumor, Cricetinae, Internal medicine, Drug Discovery, medicine, Animals, Humans, Receptor, Narcolepsy, Sulfonamides, biology, Chemistry, Hydrogen Bonding, biology.organism_classification, medicine.disease, Orexin receptor, High-Throughput Screening Assays, Endocrinology, Drug Design, Benzamides, Molecular Medicine, Calcium, Wakefulness, medicine.symptom
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4999ae7e918cd996560215c930bc2faeTest
https://doi.org/10.1021/acs.jmedchem.5b00988Test -
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المؤلفون: Annette G. Beck-Sickinger, Manja Lang, Frank M Dautzenberg, Richard Soll, Franz Dürrenberger
المصدر: Journal of Medicinal Chemistry. 47:1153-1160
مصطلحات موضوعية: Receptors, Neuropeptide, medicine.medical_specialty, Neuropeptide, Peptide, Cell Line, Receptors, G-Protein-Coupled, Structure-Activity Relationship, Orexin-A, Orexin Receptors, Internal medicine, mental disorders, Drug Discovery, medicine, Humans, Structure–activity relationship, Receptor, chemistry.chemical_classification, Orexins, Oligopeptide, Neuropeptides, digestive, oral, and skin physiology, Intracellular Signaling Peptides and Proteins, Peptide Fragments, Orexin receptor, Orexin, Endocrinology, nervous system, chemistry, Molecular Medicine, Calcium, Carrier Proteins, Oligopeptides, hormones, hormone substitutes, and hormone antagonists, psychological phenomena and processes
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c743681d48b08409a718142a09b7dbeTest
https://doi.org/10.1021/jm030982tTest -
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المؤلفون: Wanda J. Lyon, Rajesh R. Naik, Yaroslav Chushak, Nancy Kelley-Loughnane, Joshua A. Hagen, Morley O. Stone, Melanie M. Tomczak
المصدر: ACS Chemical Neuroscience. 8:2568-2568
مصطلحات موضوعية: Physiology, Cognitive Neuroscience, Analytical chemistry, chemistry.chemical_element, Neuropeptide, Cell Biology, General Medicine, Zinc, Biochemistry, Orexin-A, chemistry, Biophysics, Biological fluids, Field-effect transistor
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::1d663623edf6e8a8a7c19e5a380111f7Test
https://doi.org/10.1021/acschemneuro.7b00204Test