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1دورية أكاديمية
المؤلفون: Seetaloo, Neeleema, Zacharopoulou, Maria, Stephens, Amberley D, Kaminski Schierle, Gabriele S, Phillips, Jonathan J
المصدر: essn: 1520-6882 ; nlmid: 0370536
مصطلحات موضوعية: Humans, alpha-Synuclein, Deuterium, Hydrogen Deuterium Exchange-Mass Spectrometry, Deuterium Exchange Measurement, Parkinson Disease, Protein Conformation
وصف الملف: application/pdf
الإتاحة: https://doi.org/10.17863/CAM.92197Test
https://www.repository.cam.ac.uk/handle/1810/344774Test -
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المؤلفون: Jodi Shaulsky, Andrew C. Good, Roman V. Agafonov, Tobie D. Lee, Christopher G. Nasveschuk, Andrew J. K. Phillips, Joe Sahil Patel, Ryan E. Michael, Hongwei Huang, Scott J. Eron, Mark E. Fitzgerald, Stewart L. Fisher, Ashley A. Hart
المصدر: 'ACS Chemical Biology ', vol: 16, pages: 2228-2243 (2021)
مصطلحات موضوعية: Models, Molecular, Indoles, Protein Conformation, Cell Cycle Proteins, Protein degradation, Biochemistry, Mass Spectrometry, Piperidines, Acetamides, Humans, Molecule, Computer Simulation, Macromolecular docking, Ternary complex, Molecular Structure, Chemistry, Deuterium Exchange Measurement, General Medicine, Combinatorial chemistry, HEK293 Cells, Gene Expression Regulation, Models, Chemical, Docking (molecular), Molecular Medicine, Hydrogen–deuterium exchange, Ternary operation, Linker, Transcription Factors
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1cbcbb46e22a554e95dd60b690230ecTest
https://doi.org/10.1021/acschembio.1c00376Test -
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المصدر: ACS Chem Neurosci
مصطلحات موضوعية: Gene isoform, Physiology, Cognitive Neuroscience, Kinetics, Mutant, Peptide, Biochemistry, Article, 03 medical and health sciences, Residue (chemistry), 0302 clinical medicine, Alzheimer Disease, Amyloid precursor protein, Humans, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Amyloid beta-Peptides, biology, Deuterium Exchange Measurement, Cell Biology, General Medicine, Deuterium, Peptide Fragments, In vitro, chemistry, Biophysics, biology.protein, Hydrogen–deuterium exchange, 030217 neurology & neurosurgery, Hydrogen
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b75628e276ac4f16ab8c107ac0905a3Test
https://doi.org/10.1021/acschemneuro.1c00072Test -
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المؤلفون: Julie Ducharme, Vanja Polic, Christopher J. Thibodeaux, Karine Auclair
المصدر: ACS Chemical Biology. 16:882-890
مصطلحات موضوعية: 0301 basic medicine, Protein Conformation, Allosteric regulation, Hydrogen Deuterium Exchange-Mass Spectrometry, Plasma protein binding, Molecular Dynamics Simulation, Ligands, 01 natural sciences, Biochemistry, Structure-Activity Relationship, 03 medical and health sciences, Protein structure, Cytochrome P-450 CYP3A, Humans, Structure–activity relationship, Bioconjugation, 010405 organic chemistry, Ligand, Chemistry, Deuterium Exchange Measurement, General Medicine, Deuterium, Small molecule, 0104 chemical sciences, 3. Good health, 030104 developmental biology, Biophysics, Molecular Medicine, Hydrogen–deuterium exchange, Allosteric Site, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0676cc08793fae1577d21f2c72cee82Test
https://doi.org/10.1021/acschembio.1c00084Test -
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المؤلفون: Alice R Eddershaw, Karl Syson, Paul R. J. Davey, Gregory Hamm, Christopher D. Stubbs, Paul Clarkson, Elizabeth Underwood, Lucy V Edwardes
المصدر: Biochemistry. 59:4775-4786
مصطلحات موضوعية: Models, Molecular, Protein-Arginine N-Methyltransferases, Methyltransferase, Arginine, In Vitro Techniques, Biochemistry, Mass Spectrometry, Substrate Specificity, 03 medical and health sciences, Protein structure, Catalytic Domain, Humans, Protein Interaction Domains and Motifs, Amino Acid Sequence, Enzyme Inhibitors, Protein Structure, Quaternary, Ternary complex, Adaptor Proteins, Signal Transducing, 0303 health sciences, Chemistry, Protein arginine methyltransferase 5, 030302 biochemistry & molecular biology, Deuterium Exchange Measurement, Recombinant Proteins, Kinetics, Biophysics, Hydrogen–deuterium exchange, Steady state (chemistry)
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0c63875119c271f482688a035fe6bfcTest
https://doi.org/10.1021/acs.biochem.0c00554Test -
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المؤلفون: Darby Ball, Sheena D'Arcy, Paul Brear, Marko Hyvönen, Katherine Stott
المساهمون: D'Arcy, Sheena [0000-0001-5055-988X], Hyvönen, Marko [0000-0001-8683-4070], Apollo - University of Cambridge Repository
المصدر: J Med Chem
مصطلحات موضوعية: Stereochemistry, Allosteric regulation, Plasma protein binding, Molecular Dynamics Simulation, Crystallography, X-Ray, Ligands, Binding, Competitive, 01 natural sciences, Article, 03 medical and health sciences, chemistry.chemical_compound, Adenosine Triphosphate, Allosteric Regulation, Drug Discovery, medicine, Humans, Naphthyridines, Binding site, Protein kinase A, Casein Kinase II, Nuclear Magnetic Resonance, Biomolecular, Protein Kinase Inhibitors, 030304 developmental biology, 0303 health sciences, Chemistry, Kinase, Deuterium Exchange Measurement, Isothermal titration calorimetry, Small molecule, Adenosine, Recombinant Proteins, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Biochemistry, Original report, Phenazines, Molecular Medicine, Casein kinase 2, Adenosine triphosphate, Allosteric Site, Protein Binding, medicine.drug
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fb451b7c96794b58d85fbd55b07711aTest
https://doi.org/10.1021/acs.jmedchem.0c01173Test -
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المؤلفون: Xu Han, Masaru Miyagi, Maria de la Fuente, Marvin T. Nieman
المصدر: Biochemistry. 59:671-681
مصطلحات موضوعية: 0303 health sciences, Protease, medicine.diagnostic_test, Chemistry, medicine.medical_treatment, Proteolysis, 030302 biochemistry & molecular biology, Deuterium Exchange Measurement, Ligand (biochemistry), Biochemistry, Mass Spectrometry, 03 medical and health sciences, Thermolysin, medicine, Humans, Histidine, Receptors, Thrombin, Hydrogen–deuterium exchange, Signal transduction, Receptor
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65602521b5eb9c1a341ee854045fd23aTest
https://doi.org/10.1021/acs.biochem.9b00987Test -
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المؤلفون: Ke Sherry Li, Brett R. Beno, Ekaterina G. Deyanova, Richard Y.-C. Huang, Michael L. Gross, Elizabeth T. Schaper Bergman, Guodong Chen
المصدر: J Am Soc Mass Spectrom
مصطلحات موضوعية: Models, Molecular, Protein Conformation, Stereochemistry, DNA footprinting, Cell Cycle Proteins, 010402 general chemistry, 01 natural sciences, Article, Benzodiazepines, chemistry.chemical_compound, Protein structure, Tandem Mass Spectrometry, Structural Biology, Humans, Spectroscopy, Hydroxyl Radical, Protein footprinting, Chemistry, 010401 analytical chemistry, Deuterium Exchange Measurement, Small molecule, Footprinting, 0104 chemical sciences, Hydrogen–deuterium exchange, Hydroxyl radical, Small molecule binding, Hydrophobic and Hydrophilic Interactions, Transcription Factors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfa943384c2dea101058a6750980ae2cTest
https://doi.org/10.1007/s13361-019-02316-1Test -
9دورية أكاديمية
المؤلفون: Brear, Paul, Ball, Darby, Stott, Katherine, D'Arcy, Sheena, Hyvönen, Marko
مصطلحات موضوعية: Adenosine Triphosphate, Allosteric Regulation, Allosteric Site, Binding, Competitive, Casein Kinase II, Crystallography, X-Ray, Deuterium Exchange Measurement, Humans, Ligands, Molecular Dynamics Simulation, Naphthyridines, Nuclear Magnetic Resonance, Biomolecular, Phenazines, Protein Binding, Protein Kinase Inhibitors, Recombinant Proteins
وصف الملف: Print-Electronic; application/pdf
الإتاحة: https://doi.org/10.17863/CAM.58720Test
https://www.repository.cam.ac.uk/handle/1810/311630Test -
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المؤلفون: Adrienne A. Tymiak, Richard Y.-C. Huang, Roxana E. Iacob, Guodong Chen, Li Tao, Ling Yang, Sethu Sankaranarayanan, Michael K. Ahlijanian
المصدر: Journal of the American Society for Mass Spectrometry. 29:174-182
مصطلحات موضوعية: 0301 basic medicine, Protein Conformation, Tau protein, Enzyme-Linked Immunosorbent Assay, tau Proteins, Fibril, Proteomics, Mass spectrometry, Microtubules, 01 natural sciences, Mass Spectrometry, Progressive supranuclear palsy, 03 medical and health sciences, chemistry.chemical_compound, Structural Biology, mental disorders, medicine, Humans, Benzothiazoles, Spectroscopy, Binding Sites, biology, 010401 analytical chemistry, Antibodies, Monoclonal, Deuterium Exchange Measurement, medicine.disease, 0104 chemical sciences, Crystallography, Spectrometry, Fluorescence, 030104 developmental biology, Monomer, Epitope mapping, chemistry, Solvents, biology.protein, Biophysics, Hydrogen–deuterium exchange, Epitope Mapping
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13cec7f1eed7f934a2e8131f14ca0c08Test
https://doi.org/10.1007/s13361-017-1815-8Test