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1
المؤلفون: Karin Müller-Decker, Jens Timmer, Christian Tönsing, Nese Erdem, Ulrike Korf, Stefan Wiemann, Devina Mitra, Stephan Bernhardt, Clemens Kreutz
المصدر: Journal of Proteome Research. 18:1352-1362
مصطلحات موضوعية: Proteomics, 0301 basic medicine, Proteome, Lactate dehydrogenase A, Breast Neoplasms, medicine.disease_cause, Biochemistry, Mice, 03 medical and health sciences, Breast cancer, Glutamate-Ammonia Ligase, medicine, Animals, Humans, education, Glucose Transporter Type 1, education.field_of_study, L-Lactate Dehydrogenase, 030102 biochemistry & molecular biology, biology, Effector, Glucose transporter, General Chemistry, Metabolism, Hypoxia (medical), Hypoxia-Inducible Factor 1, alpha Subunit, medicine.disease, Gene Expression Regulation, Neoplastic, Oxygen, 030104 developmental biology, MCF-7 Cells, Cancer research, biology.protein, Heterografts, Tumor Hypoxia, Female, GLUT1, medicine.symptom, Carcinogenesis
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9360fa9072116372abfd5f21c5ddb59aTest
https://doi.org/10.1021/acs.jproteome.8b00944Test -
2
المؤلفون: Sergei Khrapunov, Robert Callender, Eric C. Chang
المصدر: Biochemistry. 56:3587-3595
مصطلحات موضوعية: 0301 basic medicine, Protein Denaturation, Protein Conformation, Swine, Biochemistry, Article, Substrate Specificity, Methylamines, 03 medical and health sciences, chemistry.chemical_compound, Lactate dehydrogenase, Enzyme Stability, Animals, Glycolysis, Psychrophile, chemistry.chemical_classification, L-Lactate Dehydrogenase, 030102 biochemistry & molecular biology, biology, Active site, NAD, Adaptation, Physiological, Perciformes, 030104 developmental biology, Enzyme, chemistry, Osmolyte, biology.protein, Thermodynamics, Lactate dehydrogenases, Mesophile
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::909acf5b616fb0ddd1c5316b83f53e5aTest
https://doi.org/10.1021/acs.biochem.7b00156Test -
3
المؤلفون: Xiaoliang Pan, Steven D. Schwartz
المصدر: The Journal of Physical Chemistry B. 119:5430-5436
مصطلحات موضوعية: Time Factors, Protein Conformation, Stereochemistry, Lactate dehydrogenase A, Context (language use), Molecular Dynamics Simulation, Nicotinamide adenine dinucleotide, Article, Cofactor, Enzyme catalysis, chemistry.chemical_compound, Lactate dehydrogenase, Pyruvic Acid, Materials Chemistry, Physical and Theoretical Chemistry, education, education.field_of_study, L-Lactate Dehydrogenase, biology, Energy landscape, NAD, Surfaces, Coatings and Films, Kinetics, chemistry, Biocatalysis, biology.protein, Thermodynamics, NAD+ kinase
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31be199ee1172943106ef71573bc4473Test
https://doi.org/10.1021/acs.jpcb.5b01840Test -
4
المؤلفون: Hua Deng, Ruel Z. B. Desamero, Robert Callender, Beining Nie
المصدر: Biochemistry. 52:1886-1892
مصطلحات موضوعية: Models, Molecular, Protein Conformation, Kinetics, Mutant, Biochemistry, Article, Geobacillus stearothermophilus, chemistry.chemical_compound, Protein structure, Catalytic Domain, Lactate dehydrogenase, Point Mutation, chemistry.chemical_classification, Oxamic Acid, L-Lactate Dehydrogenase, biology, Temperature, Tryptophan, Wild type, Active site, NAD, Crystallography, Enzyme, chemistry, biology.protein, Biophysics
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::670aa23977066499fb4d48dfef9e21dcTest
https://doi.org/10.1021/bi3017125Test -
5
المؤلفون: Rudolph E. Tanzi, Nianli Sang, Ramesh Raghupathi, Can Zhang, Haizhi Wang, Aleister J. Saunders
المصدر: Biochemistry
مصطلحات موضوعية: Leupeptins, Cathepsin L, Proteolysis, Protein degradation, Biochemistry, Article, Amyloid beta-Protein Precursor, Cell Line, Tumor, medicine, Amyloid precursor protein, Animals, Humans, Cells, Cultured, Cathepsin, L-Lactate Dehydrogenase, medicine.diagnostic_test, biology, Calpain, Chemistry, Ubiquitination, Peptide Fragments, Rats, Alpha secretase, biology.protein, Cattle, Amyloid Precursor Protein Secretases, Amyloid precursor protein secretase
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b874b95c92707fe918d58934d93328d8Test
https://doi.org/10.1021/acs.biochem.5b00329Test -
6
المؤلفون: Claire Brassington, Giles Hassall, David Whittaker, Richard A. Ward, Alexander L. Breeze, Jonathan Wingfield, Julie A. Tucker, Richard A. Norman, Ryan Greenwood, Martin Vogtherr, Stuart E. Pearson, Kevin Hudson, Jon Winter, Susan E. Critchlow, Gareth M. Davies, Alessandro T. Caputo, Michael Mrosek, Geoffrey A. Holdgate, Louise Goodwin, Jonathan Tart
المصدر: Journal of Medicinal Chemistry. 55:3285-3306
مصطلحات موضوعية: Models, Molecular, Niacinamide, Magnetic Resonance Spectroscopy, Stereochemistry, Lactate dehydrogenase A, Plasma protein binding, Crystallography, X-Ray, Isozyme, Cofactor, Structure-Activity Relationship, Catalytic Domain, Cell Line, Tumor, Drug Discovery, Animals, Humans, Structure–activity relationship, education, Enzyme Assays, Oxamic Acid, education.field_of_study, L-Lactate Dehydrogenase, Molecular Structure, biology, Chemistry, Nuclear magnetic resonance spectroscopy, Surface Plasmon Resonance, Oxidoreductase inhibitor, Small molecule, Malonates, Rats, Isoenzymes, Biochemistry, Drug Design, biology.protein, Molecular Medicine, Lactate Dehydrogenase 5, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de0ccdddf109af173b46a2cede0d6ac4Test
https://doi.org/10.1021/jm201734rTest -
7
المؤلفون: Piotr Paneth, Katarzyna Świderek
المصدر: The Journal of Physical Chemistry B. 114:3393-3397
مصطلحات موضوعية: Models, Molecular, chemistry.chemical_classification, L-Lactate Dehydrogenase, biology, Hydrogen bond, Stereochemistry, Active site, Hydrogen Bonding, Surfaces, Coatings and Films, Amino acid, chemistry.chemical_compound, chemistry, Computational chemistry, Covalent bond, Catalytic Domain, Lactate dehydrogenase, Kinetic isotope effect, Materials Chemistry, biology.protein, Protein quaternary structure, Physical and Theoretical Chemistry, Protein Structure, Quaternary
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b361098711187f6f75573bedee0988a2Test
https://doi.org/10.1021/jp100026zTest -
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المؤلفون: Xingfeng Li, Wanmeng Mu, Bo Jiang, Beilei Pan, Tao Zhang
المصدر: Journal of Agricultural and Food Chemistry. 56:2392-2399
مصطلحات موضوعية: chemistry.chemical_classification, L-Lactate Dehydrogenase, Phenylpyruvic Acids, Size-exclusion chromatography, Phenylpyruvic acid, General Chemistry, Hydrogen-Ion Concentration, respiratory system, Biology, NAD, biology.organism_classification, High-performance liquid chromatography, Enzyme assay, Lactic acid, Lactobacillus, chemistry.chemical_compound, Enzyme, Anti-Infective Agents, chemistry, Biochemistry, Lactate dehydrogenase, Lactates, biology.protein, General Agricultural and Biological Sciences
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da155693b04076185f33e6e4df98cab4Test
https://doi.org/10.1021/jf0731503Test -
9
المؤلفون: Mitchell A. Avery, Amar G. Chittiboyina, Babu L. Tekwani, Anupam Pradhan, Nicholas L. Hammond, Seoung-Ryoung Choi
المصدر: Journal of Medicinal Chemistry. 50:3841-3850
مصطلحات موضوعية: Models, Molecular, Protein Conformation, Swine, Plasmodium falciparum, Malate dehydrogenase, Antimalarials, Structure-Activity Relationship, chemistry.chemical_compound, Malate Dehydrogenase, Lactate dehydrogenase, Drug Discovery, Animals, Structure–activity relationship, chemistry.chemical_classification, Oxamic Acid, Binding Sites, L-Lactate Dehydrogenase, biology, Active site, biology.organism_classification, Recombinant Proteins, In vitro, Enzyme, chemistry, Biochemistry, Enzyme inhibitor, Drug Design, biology.protein, Molecular Medicine, Cattle
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec27ebcf2ed29c3310fddca22c737ab8Test
https://doi.org/10.1021/jm070336kTest -
10
المؤلفون: Anupam Pradhan, Mitchell A. Avery, E. Blake Watkins, Aaron B. Beeler, John M. Rimoldi, Seoung-Ryoung Choi, Babu L. Tekwani
المصدر: Journal of Combinatorial Chemistry. 9:292-300
مصطلحات موضوعية: Models, Molecular, Magnetic Resonance Spectroscopy, Plasmodium falciparum, Antimalarials, chemistry.chemical_compound, Chloroquine, Lactate dehydrogenase, medicine, Animals, Antimalarial Agent, Enzyme Inhibitors, chemistry.chemical_classification, Oxamic Acid, L-Lactate Dehydrogenase, biology, Substrate (chemistry), Active site, General Chemistry, biology.organism_classification, Amino acid, Enzyme, Biochemistry, chemistry, biology.protein, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad8b00bc8d17d1eef235466508bc3719Test
https://doi.org/10.1021/cc060110nTest