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1
المؤلفون: Michael T. Bowen, James R Krycer, Charlotte Fletcher, Lewis J. Martin, Jonathon C. Arnold, Marika Heblinski, Iain S. McGregor, Lyndsey L. Anderson, Elizabeth A. Cairns
المصدر: Journal of Natural Products. 84:1469-1477
مصطلحات موضوعية: In silico, Lactate dehydrogenase A, Pharmaceutical Science, 01 natural sciences, Cofactor, Analytical Chemistry, Cannabichromene, chemistry.chemical_compound, Lactate dehydrogenase, Drug Discovery, Binding site, education, Pharmacology, Virtual screening, education.field_of_study, biology, 010405 organic chemistry, Chemistry, Organic Chemistry, Ligand (biochemistry), 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Complementary and alternative medicine, Biochemistry, biology.protein, Molecular Medicine
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::04f519a2fc8638f2e8daaa9ae7495df1Test
https://doi.org/10.1021/acs.jnatprod.0c01281Test -
2
المؤلفون: Karin Müller-Decker, Jens Timmer, Christian Tönsing, Nese Erdem, Ulrike Korf, Stefan Wiemann, Devina Mitra, Stephan Bernhardt, Clemens Kreutz
المصدر: Journal of Proteome Research. 18:1352-1362
مصطلحات موضوعية: Proteomics, 0301 basic medicine, Proteome, Lactate dehydrogenase A, Breast Neoplasms, medicine.disease_cause, Biochemistry, Mice, 03 medical and health sciences, Breast cancer, Glutamate-Ammonia Ligase, medicine, Animals, Humans, education, Glucose Transporter Type 1, education.field_of_study, L-Lactate Dehydrogenase, 030102 biochemistry & molecular biology, biology, Effector, Glucose transporter, General Chemistry, Metabolism, Hypoxia (medical), Hypoxia-Inducible Factor 1, alpha Subunit, medicine.disease, Gene Expression Regulation, Neoplastic, Oxygen, 030104 developmental biology, MCF-7 Cells, Cancer research, biology.protein, Heterografts, Tumor Hypoxia, Female, GLUT1, medicine.symptom, Carcinogenesis
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9360fa9072116372abfd5f21c5ddb59aTest
https://doi.org/10.1021/acs.jproteome.8b00944Test -
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المؤلفون: Shunsuke Kobayashi, Akihiko Kondo, Kenji Takahashi, Hideo Kawaguchi, Tomokazu Shirai, Yota Tsuge, Kazuaki Ninomiya
المصدر: ACS Synthetic Biology. 9:814-826
مصطلحات موضوعية: 0106 biological sciences, 0303 health sciences, biology, Chemistry, Biomedical Engineering, General Medicine, Pentose phosphate pathway, 01 natural sciences, Biochemistry, Genetics and Molecular Biology (miscellaneous), Cofactor, Corynebacterium glutamicum, Metabolic engineering, 03 medical and health sciences, Metabolic pathway, chemistry.chemical_compound, Biochemistry, 010608 biotechnology, Lactate dehydrogenase, biology.protein, Glycolysis, Fermentation, 030304 developmental biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::37f74e8f6e37659c99809dede86cfcaeTest
https://doi.org/10.1021/acssynbio.9b00493Test -
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المؤلفون: Sergei Khrapunov, Robert Callender, Eric C. Chang
المصدر: Biochemistry. 56:3587-3595
مصطلحات موضوعية: 0301 basic medicine, Protein Denaturation, Protein Conformation, Swine, Biochemistry, Article, Substrate Specificity, Methylamines, 03 medical and health sciences, chemistry.chemical_compound, Lactate dehydrogenase, Enzyme Stability, Animals, Glycolysis, Psychrophile, chemistry.chemical_classification, L-Lactate Dehydrogenase, 030102 biochemistry & molecular biology, biology, Active site, NAD, Adaptation, Physiological, Perciformes, 030104 developmental biology, Enzyme, chemistry, Osmolyte, biology.protein, Thermodynamics, Lactate dehydrogenases, Mesophile
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::909acf5b616fb0ddd1c5316b83f53e5aTest
https://doi.org/10.1021/acs.biochem.7b00156Test -
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المؤلفون: Muhammad Aslam Shad, Young Ah Goo, Tanzila Rehman, Mazhar Hussain, David R. Goodlett, Mohd M. Khan, Benjamin L. Oyler
المصدر: Chemical Research in Toxicology. 29:1720-1728
مصطلحات موضوعية: 0301 basic medicine, Chromatography, biology, Arginine, Serum albumin, General Medicine, Toxicology, Blood proteins, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, Biochemistry, chemistry, Liquid chromatography–mass spectrometry, 030220 oncology & carcinogenesis, Lactate dehydrogenase, biology.protein, Alkaline phosphatase, Creatine kinase, Carbofuran
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7461f906daeff675b06987abc5fcc8f5Test
https://doi.org/10.1021/acs.chemrestox.6b00222Test -
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المؤلفون: Hua Deng, Ruel Z. B. Desamero, Robert Callender, Beining Nie
المصدر: Biochemistry. 52:1886-1892
مصطلحات موضوعية: Models, Molecular, Protein Conformation, Kinetics, Mutant, Biochemistry, Article, Geobacillus stearothermophilus, chemistry.chemical_compound, Protein structure, Catalytic Domain, Lactate dehydrogenase, Point Mutation, chemistry.chemical_classification, Oxamic Acid, L-Lactate Dehydrogenase, biology, Temperature, Tryptophan, Wild type, Active site, NAD, Crystallography, Enzyme, chemistry, biology.protein, Biophysics
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::670aa23977066499fb4d48dfef9e21dcTest
https://doi.org/10.1021/bi3017125Test -
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المؤلفون: Rudolph E. Tanzi, Nianli Sang, Ramesh Raghupathi, Can Zhang, Haizhi Wang, Aleister J. Saunders
المصدر: Biochemistry
مصطلحات موضوعية: Leupeptins, Cathepsin L, Proteolysis, Protein degradation, Biochemistry, Article, Amyloid beta-Protein Precursor, Cell Line, Tumor, medicine, Amyloid precursor protein, Animals, Humans, Cells, Cultured, Cathepsin, L-Lactate Dehydrogenase, medicine.diagnostic_test, biology, Calpain, Chemistry, Ubiquitination, Peptide Fragments, Rats, Alpha secretase, biology.protein, Cattle, Amyloid Precursor Protein Secretases, Amyloid precursor protein secretase
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b874b95c92707fe918d58934d93328d8Test
https://doi.org/10.1021/acs.biochem.5b00329Test -
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المؤلفون: Jianshe Wang, Jiayin Dai, Shengmin Yan, Wei Zhang, Hongxia Zhang
المصدر: Journal of Proteome Research. 14:330-341
مصطلحات موضوعية: Male, Proteomics, medicine.medical_specialty, Fucosyltransferase, Proteome, Blotting, Western, Biochemistry, Perfluorononanoic acid, Mice, chemistry.chemical_compound, Western blot, Internal medicine, Lactate dehydrogenase, medicine, Animals, Luciferase, Luciferases, Beta oxidation, Transaminases, Triglycerides, chemistry.chemical_classification, Fluorocarbons, Dose-Response Relationship, Drug, medicine.diagnostic_test, biology, Fatty Acids, Fatty acid, Lipid metabolism, General Chemistry, MicroRNAs, Cholesterol, Endocrinology, Gene Expression Regulation, Liver, chemistry, biology.protein, Hepatomegaly
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a9a7d89b4009518576353952e7c7dd1Test
https://doi.org/10.1021/pr500641bTest -
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المؤلفون: Claire Brassington, Giles Hassall, David Whittaker, Richard A. Ward, Alexander L. Breeze, Jonathan Wingfield, Julie A. Tucker, Richard A. Norman, Ryan Greenwood, Martin Vogtherr, Stuart E. Pearson, Kevin Hudson, Jon Winter, Susan E. Critchlow, Gareth M. Davies, Alessandro T. Caputo, Michael Mrosek, Geoffrey A. Holdgate, Louise Goodwin, Jonathan Tart
المصدر: Journal of Medicinal Chemistry. 55:3285-3306
مصطلحات موضوعية: Models, Molecular, Niacinamide, Magnetic Resonance Spectroscopy, Stereochemistry, Lactate dehydrogenase A, Plasma protein binding, Crystallography, X-Ray, Isozyme, Cofactor, Structure-Activity Relationship, Catalytic Domain, Cell Line, Tumor, Drug Discovery, Animals, Humans, Structure–activity relationship, education, Enzyme Assays, Oxamic Acid, education.field_of_study, L-Lactate Dehydrogenase, Molecular Structure, biology, Chemistry, Nuclear magnetic resonance spectroscopy, Surface Plasmon Resonance, Oxidoreductase inhibitor, Small molecule, Malonates, Rats, Isoenzymes, Biochemistry, Drug Design, biology.protein, Molecular Medicine, Lactate Dehydrogenase 5, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de0ccdddf109af173b46a2cede0d6ac4Test
https://doi.org/10.1021/jm201734rTest -
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المؤلفون: Hua Deng, Robert Callender, R. Brian Dyer, Huo Lei Peng
المصدر: Biochemistry
مصطلحات موضوعية: Swine, Stereochemistry, Nicotinamide adenine dinucleotide, 010402 general chemistry, 01 natural sciences, Biochemistry, Article, Catalysis, Cofactor, chemistry.chemical_compound, Catalytic Domain, Lactate dehydrogenase, Pyruvic Acid, Spectroscopy, Fourier Transform Infrared, Animals, Hydro-Lyases, Stochastic Processes, biology, Nicotinamide, 010405 organic chemistry, Hydrogen bond, Active site, NAD, 0104 chemical sciences, chemistry, biology.protein, Pyruvic acid, NAD+ kinase, Energy Metabolism
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca0304b7e6d2e45902e8559a72e1aecbTest
https://doi.org/10.1021/bi500215aTest