دورية أكاديمية
Chicory Roots for Prebiotics and Appetite Regulation: A Pilot Study in Mice.
| العنوان: | Chicory Roots for Prebiotics and Appetite Regulation: A Pilot Study in Mice. |
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| المؤلفون: | Foure, Marion, Dugardin, Camille, Foligne, Benoit, Hance, Philippe, Cadalen, Thierry, Delcourt, Abigael, Taminiau, Bernard, Daube, Georges, Ravallec, Rozenn, Cudennec, Benoit, Hilbert, Jean-Louis, Lucau-Danila, Anca |
| المصدر: | Journal of Agricultural and Food Chemistry, 66 (25), 6439-6449 (2018) |
| بيانات النشر: | American Chemical Society |
| سنة النشر: | 2018 |
| المجموعة: | University of Liège: ORBi (Open Repository and Bibliography) |
| مصطلحات موضوعية: | Animals, Appetite Regulation/drug effects, Bacteria/classification/genetics/isolation & purification, Chicory/chemistry/genetics/metabolism, Digestion/drug effects, Gastrointestinal Microbiome/drug effects, Gastrointestinal Tract/metabolism/microbiology, Mice, Plant Extracts/metabolism/pharmacology, Prebiotics/analysis, Cichorium intybus, metabolomics, metagenetics, prebiotics, satiety hormones, Life sciences, Microbiology, Sciences du vivant, Microbiologie |
| الوصف: | peer reviewed ; The objectives of this work are to address the prebiotic effects of chicory ( Cichorium intybus) together with its possible role in appetite control. We compared nine chicory genotypes in order to determine if variations in the content of metabolites in the roasted roots would lead to modifications in release of satiety hormones and in composition of gut microbiota. To this aim, a 5-week dietary-intervention study was achieved using mice fed with distinct chicory-based preparations. A 16S rRNA gene-based metagenetic analysis of fecal microbiota was performed. In vitro gastrointestinal digestions were performed in order to study the effect of chicory intestinal digests on gut hormone regulation in enteroendocrine cells. Firmicutes/Bacteroidetes ratio and gut bacterial groups, such as Alloprevotella, Blautia, Alistipes, and Oscillibacter, were found to be modulated by chicory. On the other hand, CCK and GLP-1 satiety hormones were demonstrated to be significantly increased by chicory in vitro. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 0021-8561 1520-5118 |
| العلاقة: | urn:issn:0021-8561; urn:issn:1520-5118; https://orbi.uliege.be/handle/2268/238279Test; info:hdl:2268/238279; https://orbi.uliege.be/bitstream/2268/238279/1/acs.jafc.8b01055.pdfTest; scopus-id:2-s2.0-85048365276; info:pmid:29873488 |
| DOI: | 10.1021/acs.jafc.8b01055 |
| الإتاحة: | https://doi.org/10.1021/acs.jafc.8b01055Test https://orbi.uliege.be/handle/2268/238279Test https://orbi.uliege.be/bitstream/2268/238279/1/acs.jafc.8b01055.pdfTest |
| حقوق: | open access ; http://purl.org/coar/access_right/c_abf2Test ; info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.5A48DFBE |
| قاعدة البيانات: | BASE |
| تدمد: | 00218561 15205118 |
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| DOI: | 10.1021/acs.jafc.8b01055 |