يعرض 1 - 10 نتائج من 144 نتيجة بحث عن '"Guanosine Triphosphatase"', وقت الاستعلام: 0.71s تنقيح النتائج
  1. 1
    دورية أكاديمية
    Multiplexed Real-Time NMR GTPase Assay for Simultaneous Monitoring of Multiple Guanine Nucleotide Exchange Factor Activities from Human Cancer Cells and Organoids.

    المؤلفون: Gebregiworgis, Teklab1, Marshall, Christopher B.1 chris.marshall@uhnresearch.ca, Nishikawa, Tadateru1, Radulovich, Nikolina1, Sandí, María-José1, Zhenhao Fang1,2, Rottapel, Robert1,2, Ming-Sound Tsao1,2,3, Mitsuhiko Ikura1,2 mitsu.ikura@uhnresearch.ca

    المصدر: Journal of the American Chemical Society. 4/4/2018, Vol. 140 Issue 13, p4473-4476. 4p.

    مصطلحات موضوعية: *GUANOSINE triphosphatase, *GUANINE nucleotide exchange factors, *CANCER cells, *ORGANOIDS, *RNA sequencing


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  2. 2
    دورية أكاديمية
    Identification of the Privileged Position in the Imidazo[1,2-a]pyridine Ring of Phosphonocarboxylates for Development of Rab Geranylgeranyl Transferase (RGGT) Inhibitors.

    المؤلفون: Kaźmierczak, Aleksandra1, Kusy, Damian2, Niinivehmas, Sanna P.3, Gmach, Joanna2, Joachimiak, Łukasz2, Pentikäinen, Olli T.3,4, Gendaszewska-Darmach, Edyta1, Błażewska, Katarzyna M.2 katarzyna.blazewska@p.lodz.pl

    المصدر: Journal of Medicinal Chemistry. 11/9/2017, Vol. 60 Issue 21, p8781-8800. 20p.

    مصطلحات موضوعية: *GUANOSINE triphosphatase, *RHO GTPases, *CHEMICAL modification of proteins, *IMIDAZOLES, *PYRIDINE, *RING formation (Chemistry), *GERANYLGERANYLTRANSFERASES, *CANCER cell proliferation


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  3. 3
    دورية أكاديمية
    Pharmacophore Mapping of Thienopyrimidine-Based Monophosphonate (ThP-MP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase.

    المؤلفون: Park, Jaeok1, Chun Yuen Leung2, Matralis, Alexios N.2, Lacbay, Cyrus M.2, Tsakos, Michail2, Fernandez De Troconiz, Guillermo2, Berghuis, Albert M.1,3, Tsantrizos, Youla S.1,2,3 Youla.tsantrizos@mcgill.ca

    المصدر: Journal of Medicinal Chemistry. 3/9/2017, Vol. 60 Issue 5, p2119-2134. 16p.

    مصطلحات موضوعية: *GUANOSINE triphosphatase, *POST-translational modification, *ISOPRENYLATION, *TARGETED drug delivery, *ALLOSTERIC regulation


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  4. 4
    دورية أكاديمية
    Molecular Dynamics Simulations Reveal Isoform Specific Contact Dynamics between the Plexin Rho GTPase Binding Domain (RBD) and Small Rho GTPases Rac1 and Rnd1.

    المؤلفون: Liqun Zhang1 lzhang@tntech.edu, Buck, Matthias2,3,4,5,6 matthias.buck@case.edu

    المصدر: Journal of Physical Chemistry B. Feb2017, Vol. 121 Issue 7, p1485-1498. 14p.

    مصطلحات موضوعية: *ANALYTICAL mechanics, *GUANOSINE triphosphatase, *MOLECULAR interactions, *MOLECULAR physics, *PHOSPHATASES


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  5. 5
    دورية أكاديمية
    Pyrimidine-Based Inhibitors of Dynamin I GTPase Activity: Competitive Inhibition at the Pleckstrin Homology Domain.

    المؤلفون: Odell, Luke R.1, Abdel-Hamid, Mohammed K.1,2, Hill, Timothy A.1, Chau, Ngoc3, Young, Kelly A.1, Deane, Fiona M.1, Sakoff, Jennette A.4, Andersson, Sofia5, Daniel, James A.3, Robinson, Phillip J.3, McCluskey, Adam1 Adam.McCluskey@newcastle.edu.au

    المصدر: Journal of Medicinal Chemistry. Jan2017, Vol. 60 Issue 1, p349-361. 13p.

    مصطلحات موضوعية: *GUANOSINE triphosphatase, *CLATHRIN, *PYRIMIDINES, *DYNAMIN (Genetics), *ENZYME inhibitors


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  6. 6
    دورية أكاديمية
    Structural Characterization of Arginine Fingers: Identification of an Arginine Finger for the Pyrophosphatase dUTPases.

    المؤلفون: Nagy, Gergely N.1,2 nagy.gergely@ttk.mta.hu, Suardíaz, Reynier3, Lopata, Anna2, Ozohanics, Olivér4, Vékey, Kaároly5, Brooks, Bernard R.6, Leveles, Ibolya1,2, Tóth, Judit2, Vértessy, Beata G.1,2 vertessy@mail.bme.hu, Rosta, Edina3 edina.rosta@kcl.ac.uk

    المصدر: Journal of the American Chemical Society. 11/16/2016, Vol. 138 Issue 45, p15035-15045. 11p.

    مصطلحات موضوعية: *ARGININE, *GUANOSINE triphosphatase, *ADENOSINE triphosphatase, *NUCLEOTIDE sequence, *INORGANIC pyrophosphatase


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  7. 7
    دورية أكاديمية
    GTP-Specific Fab Fragment-Based GTPase Activity Assay.

    المؤلفون: Kopra, Kari1 kari.kopra@utu.fi, Rozwandowicz-Janse, Anita2, Syrjänpää, Markku2,3, Blaževitš, Olga4, Ligabue, Alessio4, Veltel, Stefan5, Lamminmäk, Urpo3, Abankwa, Daniel4, Härmä, Harri1

    المصدر: Analytical Chemistry. 3/17/2015, Vol. 87 Issue 6, p3527-3534. 5p.

    مصطلحات موضوعية: *GUANOSINE triphosphatase, *PROTEINS, *BIOTIN, *IMMUNOGLOBULINS, *BIOMOLECULES


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  8. 8
    دورية أكاديمية
    Identification of the FirstInhibitor of the GBP1:PIM1 Interaction. Implications for the Developmentof a New Class of Anticancer Agents against Paclitaxel Resistant CancerCells.

    المؤلفون: Andreoli, Mirko1, Persico, Marco1, Kumar, Ajay1, Orteca, Nausicaa1, Kumar, Vineet1, Pepe, Antonella1, Mahalingam, Sakkarapalayam1, Alegria, Antonio E.1, Petrella, Lella1, Sevciunaite, Laima1, Camperchioli, Alessia1, Mariani, Marisa1, Di Dato, Antonio1, Novellino, Ettore1, Scambia, Giovanni1, Malhotra, Sanjay V.1, Ferlini, Cristiano1, Fattorusso, Caterina1

    المصدر: Journal of Medicinal Chemistry. Oct2014, Vol. 57 Issue 19, p7916-7932. 17p.

    مصطلحات موضوعية: *GUANOSINE triphosphatase, *ANTINEOPLASTIC agents, *DRUG development, *TUBULINS, *DRUG resistance, *MICROTUBULES


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  9. 9
    دورية أكاديمية
    Structureand Dynamics Analysis on Plexin-B1 Rho GTPaseBinding Domain as a Monomer and Dimer.

    المؤلفون: Zhang, Liqun1, Centa, Thomas1, Buck, Matthias1

    المصدر: Journal of Physical Chemistry B. Jul2014, Vol. 118 Issue 26, p7302-7311. 10p.

    مصطلحات موضوعية: *PLEXINS, *GUANOSINE triphosphatase, *BINDING sites, *MONOMERS, *PRINCIPAL components analysis, *ENTROPY


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  10. 10
    دورية أكاديمية
    Superoxide Inhibits Guanine Nucleotide Exchange Factor (GEF) Action on Ras, but not on Rho, through Desensitization of Ras to GEF.

    المؤلفون: Wey, Michael1, Phan, Vinh1, Yepez, Gerardo1, Heo, Jongyun1 jheo@uta.edu

    المصدر: Biochemistry. 1/28/2014, Vol. 53 Issue 3, p518-532. 15p.

    مصطلحات موضوعية: *SUPEROXIDES, *GUANOSINE triphosphatase, *GUANINE nucleotide exchange factors, *PATHOLOGICAL physiology, *OXIDIZING agents


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