التفاصيل البيبلوغرافية
| العنوان: |
Four Matrine-Based Alkaloids with Antiviral Activities against HBV from the Seeds of Sophora alopecuroides. |
| المؤلفون: |
Yu-Bo Zhang1,2, Xiao-Li Zhang1,2, Neng-Hua Chen1,2, Zhong-Nan Wu1,2, Wen-Cai Ye1,2 chyewc@gmail.com, Yao-Lan Li1,2 tliyl@jnu.edu.cn, Guo-Cai Wang1,2 twangguocai@jnu.edu.cn |
| المصدر: |
Organic Letters. Jan2017, Vol. 19 Issue 2, p424-427. 4p. |
| مصطلحات موضوعية: |
*ALKALOIDS, *LEGUME seeds, *SOPHORA alopecuroides, *ANTIVIRAL agents, *HEPATITIS B virus |
| مستخلص: |
Four novel matrine-based alkaloids (1-4) were isolated from the seeds of Sophora alopecuroides. Compounds 1 and 2 possess unprecedented 6/6/6/4 and 6/5/6/6 ring systems, respectively, while 3 and 4 are a pair of stereoisomeric matrine-acetophenone alkaloids with an unusual skeleton. Their structures were elucidated by means of spectroscopic methods and single-crystal X-ray diffraction. Hypothetical biogenetic pathways for 1-4 are proposed, and their antiviral activities are also discussed. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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