المؤلفون: Anne Durandy, Fabien Garçon, Len R. Stephens, Jeffrey C. Barrett, Sergey Nejentsev, Anna Kielkowska, James Curtis, Menna R. Clatworthy, Dinakantha S. Kumararatne, Edwin R. Chilvers, Edward Banham-Hall, Andrew J. Cant, Oscar Vadas, George Farmer, Klaus Okkenhaug, Sven Kracker, Jatinder K. Juss, Deirdre Cilliers, Katherine G. Blake-Palmer, Olga Perisic, Alison M. Condliffe, Jonathan Clark, James Morris, Anita Chandra, Helen Baxendale, Vincent Plagnol, Rainer Doffinger, Capucine Picard, Mario Abinun, Christine A Fiddler, Timothy Ronan Leahy, Ivan Angulo, Mailis Maes, Nada Jabado, Phillip T. Hawkins, Marianne Debré, Tanya I. Coulter, Changxin Wu, Roger L. Williams, Gabriela Barcenas-Morales, Deborah J. Smyth, Gašper Markelj, Alain Fischer, Isabelle Pellier

المصدر: Science; Vol 342
Science

مصطلحات موضوعية: Class I Phosphatidylinositol 3-Kinases, Activated PI3K-delta syndrome, Gene mutation, medicine.disease_cause, Phosphatidylinositol 3-Kinases, 03 medical and health sciences, 0302 clinical medicine, Phosphatidylinositol Phosphates, PIK3R1, medicine, Humans, Genetic Predisposition to Disease, Lymphocytes, Kinase activity, Respiratory Tract Infections, 030304 developmental biology, 0303 health sciences, Mutation, Multidisciplinary, Phosphoinositide 3-kinase, biology, Immunologic Deficiency Syndromes, Respiratory infection, Pedigree, 3. Good health, P110δ, Immunology, biology.protein, Proto-Oncogene Proteins c-akt, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::045a58f41268fc11df2b14a1b2e91763Test
https://doi.org/10.1126/science.1243292Test

المؤلفون: Antonio J. Oliveira-dos-Santos, Josef M. Penninger, Junko Irie-Sasaki, Akira Suzuki, Ivona Kozieradzki, Andrew Wakeham, Takehiko Sasaki, Brad Bolon, William L. Stanford, Annick Itie, Dennis Bouchard, Nicholas Joza, Tak W. Mak, Pamela S. Ohashi, Russell G. Jones

المصدر: Science. 287:1040-1046

مصطلحات موضوعية: Thymocyte, Multidisciplinary, medicine.anatomical_structure, Kinase, P110δ, T cell, Ribosomal protein s6, medicine, Biology, Signal transduction, Protein kinase A, Protein kinase B, Cell biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::00515b3af3c4af1d0531a6b69bf6ba24Test
https://doi.org/10.1126/science.287.5455.1040Test