التفاصيل البيبلوغرافية
| العنوان: |
SLC7A11 expression is associated with seizures and predicts poor survival in patients with malignant glioma |
| المؤلفون: |
Robert, Stephanie M., Buckingham, Susan C., Campbell, Susan L., Robel, Stefanie, Holt, Kenneth T., Ogunrinu-Babarinde, Toyin, Warren, Paula P., White, David M., Reid, Meredith A., Eschbacher, Jenny M., Berens, Michael E., Lahti, Adrienne C., Nabors, Louis B., Sontheimer, Harald |
| المساهمون: |
NIH, Ben & Catherine Ivy Foundation |
| المصدر: |
Science Translational Medicine ; volume 7, issue 289 ; ISSN 1946-6234 1946-6242 |
| بيانات النشر: |
American Association for the Advancement of Science (AAAS) |
| سنة النشر: |
2015 |
| الوصف: |
SLC7A11, the catalytic subunit of the cystine/glutamate antiporter, System x c − (SXC), is up-regulated in a subpopulation of patient gliomas, where it is responsible for excitotoxic glutamate release, accelerated tumor growth, and tumor-associated seizures. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| DOI: |
10.1126/scitranslmed.aaa8103 |
| الإتاحة: |
https://doi.org/10.1126/scitranslmed.aaa8103Test |
| حقوق: |
http://www.sciencemag.org/about/science-licenses-journal-article-reuseTest |
| رقم الانضمام: |
edsbas.9F4EA2CF |
| قاعدة البيانات: |
BASE |
