التفاصيل البيبلوغرافية
| العنوان: |
Pharmacological rescue of diabetic skeletal stem cell niches. |
| المؤلفون: |
Tevlin, Ruth, Eun Young Seo, Marecic, Owen, McArdle, Adrian, Xinming Tong, Zimdahl, Bryan, Malkovski, Andrey, Sinha, Rahul, Gulati, Gunsagar, Xiyan Li, Wearda, Taylor, Morganti, Rachel, Lopez, Michael, Ransom, Ryan C., Duldulao, Christopher R., Rodrigues, Melanie, Nguyen, Allison, Januszyk, Michael, Maan, Zeshaan, Paik, Kevin |
| المصدر: |
Science Translational Medicine; 1/11/2017, Vol. 9 Issue 372, p1-11, 11p, 2 Color Photographs, 6 Graphs |
| مصطلحات موضوعية: |
STEM cells, DIABETES, WOUND healing, PROGENITOR cells, LABORATORY mice |
| مستخلص: |
The article presents a study which analyzed intrinsic and extrinsic determinants of mouse skeletal stem cell (mSSC) function to identify specific mSSC-related abnormalities that could impair skeletal repair in diabetic mice. Topics discussed include link between diabetes mellitus and impaired bone healing, molecular characterization of the skeletal niche points to therapeutic strategies, and isolation of skeletal progenitor cells. |
| قاعدة البيانات: |
Complementary Index |
