التفاصيل البيبلوغرافية
| العنوان: |
RACK7 recognizes H3.3G34R mutation to suppress expression of MHC class II complex components and their delivery pathway in pediatric glioblastoma. |
| المؤلفون: |
Fangfang Jiao1, Ze Li2,3, Chen He4, Wenqi Xu1, Gensheng Yang1, Tingting Liu5, Hongjie Shen1, Jiajun Cai6, Anastas, Jamie N.7, Ying Mao6, Yongchun Yu5, Fei Lan8, Yujiang Geno Shi9, Jones, Chris10, Yanhui Xu2,3, Baker, Suzanne J.4 suzanne.baker@stjude.org, Yang Shi7 yshi@hms.harvard.edu, Rui Guo1 guorui@fudan.edu.cn |
| المصدر: |
Science Advances. 7/15/2020, Vol. 6 Issue 29, p1-15. 15p. |
| مصطلحات موضوعية: |
*PROGRAMMED cell death 1 receptors, *HEMAGGLUTININ, *GLIOBLASTOMA multiforme, *MEDICAL sciences, *PLATELET-derived growth factor receptors, *GLIAL fibrillary acidic protein, *INTERMEDIATE filament proteins, *GENE enhancers |
| مستخلص: |
The article presents a research article RACK7 antibody recognizes H3.3G34R mutation to suppress expression of major histocompatibility complex (MHC) class II complex components and their delivery pathway in pediatric glioblastoma. Topics include findings suggest a potential molecular mechanism by which H3.3G34R promotes cancer; and histone H3, mutations were also identified in all four core histones in human cancers. |
| قاعدة البيانات: |
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