التفاصيل البيبلوغرافية
العنوان: |
Targeting brain metastases with ultrasmall theranostic nanoparticles, a first-in-human trial from an MRI perspective. |
المؤلفون: |
Verry, Camille1, Dufort, Sandrine2, Lemasson, Benjamin3, Grand, Sylvie1 yannick.cremillieux@u-bordeaux.fr, Pietras, Johan4, Troprès, Irène4, Crémillieux, Yannick5, Lux, François6, Mériaux, Sébastien7, Larrat, Benoit7, Balosso, Jacques1, Le Duc, Géraldine2, Barbier, Emmanuel L.3, Tillement, Olivier6 |
المصدر: |
Science Advances. 7/15/2020, Vol. 6 Issue 29, p1-9. 9p. |
مصطلحات موضوعية: |
*NANOPARTICLES, *BRAIN metastasis, *MAGNETIC resonance angiography, *NANOMEDICINE, *LINEAR accelerators, *METASTATIC breast cancer |
مستخلص: |
The article informs about first-in-human trial for targeting brain metastases with ultrasmall theranostic nanoparticles. Topics include use of radiosensitizing nanoparticles with both imaging and therapeutic properties on the same nano-object is regarded as a major and promising approach to improve the effectiveness of radiotherapy; and nanoparticles were found to accumulate and to increase image contrast in all types of brain metastases equivalent to that of a clinically used contrast agent. |
قاعدة البيانات: |
Academic Search Index |