دورية أكاديمية

Imaging mitochondrial dynamics in human skin reveals depth-dependent hypoxia and malignant potential for diagnosis.

التفاصيل البيبلوغرافية
العنوان: Imaging mitochondrial dynamics in human skin reveals depth-dependent hypoxia and malignant potential for diagnosis.
المؤلفون: Pouli, Dimitra, Balu, Mihaela, Alonzo, Carlo A., Zhiyi Liu, Quinn, Kyle P., Rius-Diaz, Francisca, Harris, Ronald M., Kelly, Kristen M., Tromberg, Bruce J., Georgakoudi, Irene
المصدر: Science Translational Medicine; 11/30/2016, Vol. 8 Issue 367, p1-11, 11p, 5 Color Photographs
مصطلحات موضوعية: MITOCHONDRIAL proteins, HYPOXEMIA, NICOTINAMIDE adenine dinucleotide phosphate, FLUORESCENCE, MITOCHONDRIA
مستخلص: The article discusses research which showed that imaging of mitochondrial dynamics within human skin showed depth-dependent hypoxia. Topics discussed include monitoring by endogenous two-photon-excited fluorescence from the reduced metabolic coenzyme nicotinamide adenine dinucleotide (NADH), in vivo outcomes resulting from NADH fluorescence changes and varied mitochondrial organization patterns with historical stratification and intraepithelial mitochondrial protein expression.
قاعدة البيانات: Complementary Index
الوصف
تدمد:19466234
DOI:10.1126/scitranslmed.aag2202