التفاصيل البيبلوغرافية
| العنوان: |
Structure of Complement Receptor 2 in Complex with Its C3d Ligand. |
| المؤلفون: |
Szakonyi, Gerda, Guthridge, Joel M., Li, Dawei, Young, Kendra, Holers, V. Michael, Chen, Xiaojiang S. |
| المصدر: |
Science. 6/1/2001, Vol. 292 Issue 5522, p1725-1728. 4p. 3 Color Photographs, 1 Chart, 1 Graph. |
| مصطلحات موضوعية: |
*CELL receptors, *LIGANDS (Biochemistry), *STRUCTURE-activity relationships |
| مستخلص: |
Describes the x-ray structure of the complement receptor 2 (CR2) domain in complex with C3d at 2.0 angstroms. Role of CR2 as a receptor that amplifies B lymphocyte activation; Bridging of the innate and adaptive immune systems; Understanding of receptor-ligand interactions; Potential target sites for molecular drug design. |
| قاعدة البيانات: |
Academic Search Index |
