دورية أكاديمية
PP2Cδ inhibits p300-mediated p53 acetylation via ATM/BRCA1 pathway to impede DNA damage response in breast cancer
| العنوان: | PP2Cδ inhibits p300-mediated p53 acetylation via ATM/BRCA1 pathway to impede DNA damage response in breast cancer |
|---|---|
| المؤلفون: | Li, Qun, Hao, Qiongyu, Cao, Wei, Li, Jieqing, Wu, Ke, Elshimali, Yahya, Zhu, Donghui, Chen, Qiao-Hong, Chen, Guanglin, Pollack, Jonathan R., Vadgama, Jay, Wu, Yong |
| المصدر: | Science Advances, 5(10), American Association for the Advancement of Science, October 2019 |
| بيانات النشر: | American Association for the Advancement of Science |
| سنة النشر: | 2019 |
| المجموعة: | University of North Texas: UNT Digital Library |
| مصطلحات موضوعية: | cancers, PP2Cδ, p53 acetylation |
| الوصف: | Article describes study which indicates that nuclear type 2C protein phosphatase (PP2Cδ) impairs p53 acetylation and DNA damage response by compromising BRCA1 function in breast cancer development. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | 12 p.; Text |
| اللغة: | English |
| العلاقة: | https://digital.library.unt.edu/ark:/67531/metadc1703597Test/; ark: ark:/67531/metadc1703597 |
| DOI: | 10.1126/sciadv.aaw8417 |
| الإتاحة: | https://doi.org/10.1126/sciadv.aaw8417Test https://digital.library.unt.edu/ark:/67531/metadc1703597Test/ |
| حقوق: | Public ; Attribution Noncommercial |
| رقم الانضمام: | edsbas.7FF636EA |
| قاعدة البيانات: | BASE |
| DOI: | 10.1126/sciadv.aaw8417 |
|---|