نتائج البحث - "egfr inhibitors"

1

A Novel Third-generation EGFR Tyrosine Kinase Inhibitor Abivertinib for EGFR T790M-mutant Non–Small Cell Lung Cancer: a Multicenter Phase I/II Study

المؤلفون: Qing Zhou, Lin Wu, Pei Hu, Tongtong An, Jianying Zhou, Li Zhang, Xiao-Qing Liu, Feng Luo, Xin Zheng, Ying Cheng, Nong Yang, Junling Li, Jifeng Feng, Baohui Han, Yong Song, Kai Wang, Jian Fang, Hong Zhao, Yongqian Shu, Xiao-Yan Lin, Zhihong Chen, Bin Gan, Wan-Hong Xu, Wei Tang, Xiaoying Zhang, Jin-Ji Yang, Xiao Xu, Yi-Long Wu

المصدر: Clinical Cancer Research. 28:1127-1135

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ef172334327b78f078f2ebc1a309df2Test
https://doi.org/10.1158/1078-0432.ccr-21-2595Test

2

Membrane-Associated RING-CH 8 Functions as a Novel PD-L1 E3 Ligase to Mediate PD-L1 Degradation Induced by EGFR Inhibitors

المؤلفون: Wenyi Wei, Songqing Fan, Guoqing Qian, Karin A. Vallega, Qiming Wang, Yunfu Deng, Zhen Chen, Suresh S. Ramalingam, Jianping Guo, Taofeek K. Owonikoko, Changjiang Hu, Shi-Yong Sun

المصدر: Mol Cancer Res

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49618826ca7fd0d978235270c398bde2Test
https://doi.org/10.1158/1541-7786.mcr-21-0147Test

3

Combinations with Allosteric SHP2 Inhibitor TNO155 to Block Receptor Tyrosine Kinase Signaling

المصدر: Clinical Cancer Research. 27:342-354

مصطلحات موضوعية: Proto-Oncogene Proteins B-raf, 0301 basic medicine, MAPK/ERK pathway, Cancer Research, Programmed Cell Death 1 Receptor, Allosteric regulation, Protein Tyrosine Phosphatase, Non-Receptor Type 11, medicine.disease_cause, Receptor tyrosine kinase, Proto-Oncogene Proteins p21(ras), Mice, 03 medical and health sciences, 0302 clinical medicine, Allosteric Regulation, Cell Line, Tumor, Neoplasms, Antineoplastic Combined Chemotherapy Protocols, Tumor-Associated Macrophages, medicine, Animals, Humans, Immune Checkpoint Inhibitors, Protein Kinase Inhibitors, EGFR inhibitors, Tumor microenvironment, biology, Chemistry, Cyclin-Dependent Kinase 4, Cancer, Drug Synergism, Cyclin-Dependent Kinase 6, medicine.disease, Xenograft Model Antitumor Assays, ErbB Receptors, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Mutation, Cancer cell, biology.protein, Cancer research, Female, KRAS

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ce3c3f6b2f214726db8bd9a82f04ec4Test
https://doi.org/10.1158/1078-0432.ccr-20-2718Test

4

CXCR7 Reactivates ERK Signaling to Promote Resistance to EGFR Kinase Inhibitors in NSCLC

المصدر: CANCER RESEARCH
r-FISABIO. Repositorio Institucional de Producción Científica
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r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
Cancer research, vol 79, iss 17
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Cancer Research, Lung Neoplasms, Drug Resistance, Drug resistance, Transgenic, Mice, Chemokine receptor, 0302 clinical medicine, Neoplasms, Carcinoma, Non-Small-Cell Lung, Receptors, Medicine, Non-Small-Cell Lung, CXCR, Receptor, Lung, beta-Arrestins, Cancer, EGFR inhibitors, Tumor, Kinase, Lung Cancer, ErbB Receptors, Oncology, 5.1 Pharmaceuticals, 030220 oncology & carcinogenesis, Development of treatments and therapeutic interventions, Tyrosine kinase, Epithelial-Mesenchymal Transition, MAP Kinase Signaling System, Oncology and Carcinogenesis, Mice, Transgenic, Article, Cell Line, Experimental, 03 medical and health sciences, Clinical Research, Cell Line, Tumor, Animals, Humans, Oncology & Carcinogenesis, Protein Kinase Inhibitors, Receptors, CXCR, business.industry, Carcinoma, Neoplasms, Experimental, respiratory tract diseases, 030104 developmental biology, Protein kinase domain, Drug Resistance, Neoplasm, Mutation, Cancer research, Neoplasm, business