نتائج البحث

المصدر: Høgdall, D, O'Rourke, C J, Dehlendorff, C, Larsen, O F, Jensen, L H, Johansen, A Z, Dang, H, Factor, V M, Grunnet, M, Mau-Sørensen, M, Oliveira, D V N P, Linnemann, D, Boisen, M K, Wang, X W, Johansen, J S & Andersen, J B 2020, ' Serum IL6 as a Prognostic Biomarker and IL6R as a Therapeutic Target in Biliary Tract Cancers ', Clinical Cancer Research, vol. 26, no. 21, pp. 5655-5667 . https://doi.org/10.1158/1078-0432.CCR-19-2700Test
Clin Cancer Res

مصطلحات موضوعية: Adult, Male, musculoskeletal diseases, 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Locally advanced, Inflammation, Deoxycytidine, Article, Disease-Free Survival, Mice, 03 medical and health sciences, 0302 clinical medicine, In vivo, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, Biomarkers, Tumor, medicine, Animals, Humans, Antigens, Tumor-Associated, Carbohydrate, Prognostic biomarker, Chitinase-3-Like Protein 1, Aged, Cell Proliferation, Aged, 80 and over, Interleukin-6, Proportional hazards model, business.industry, Palliative Care, Middle Aged, Prognosis, Receptors, Interleukin-6, Gemcitabine, Progression-Free Survival, Clinical trial, Biliary Tract Neoplasms, 030104 developmental biology, Biliary tract, 030220 oncology & carcinogenesis, Female, medicine.symptom, business, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db1883a3389ee7e27bcc0a6669a1e847Test
https://doi.org/10.1158/1078-0432.ccr-19-2700Test

5

Changes in Peripheral and Local Tumor Immunity after Neoadjuvant Chemotherapy Reshape Clinical Outcomes in Patients with Breast Cancer

المصدر: Clin Cancer Res

مصطلحات موضوعية: Adult, 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Paclitaxel, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Triple Negative Breast Neoplasms, Disease, CD8-Positive T-Lymphocytes, Article, B7-H1 Antigen, 03 medical and health sciences, Lymphocytes, Tumor-Infiltrating, 0302 clinical medicine, Breast cancer, Albumins, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, Tumor Microenvironment, medicine, Humans, Aged, Chemotherapy, business.industry, Immunotherapy, Middle Aged, Gene signature, Prognosis, medicine.disease, Neoadjuvant Therapy, Progression-Free Survival, Neoplasm Proteins, Gene Expression Regulation, Neoplastic, Treatment Outcome, 030104 developmental biology, 030220 oncology & carcinogenesis, Biomarker (medicine), Female, Cytokine secretion, Neoplasm Recurrence, Local, business, CD8

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bcb791e74b1e7256046bab4264aacd2Test
https://doi.org/10.1158/1078-0432.ccr-19-3685Test

6

Angiogenic and Immune-Related Biomarkers and Outcomes Following Axitinib/Pembrolizumab Treatment in Patients with Advanced Renal Cell Carcinoma

المؤلفون: Bradley Rosbrook, Ulka N. Vaishampayan, Toni K. Choueiri, Saby George, David F. McDermott, Daniel C. Cho, Elizabeth R. Plimack, Igor Puzanov, Mayer Fishman, Jean-Francois Martini, Michael B. Atkins, Jamal Tarazi, Kathrine C. Fernandez

المصدر: Clinical Cancer Research. 26:5598-5608

مصطلحات موضوعية: Adult, Male, Oncology, Cancer Research, medicine.medical_specialty, Axitinib, Protein Tyrosine Phosphatase, Non-Receptor Type 11, Pembrolizumab, Antibodies, Monoclonal, Humanized, Granzymes, Interferon-gamma, 03 medical and health sciences, 0302 clinical medicine, Immune system, Lipocalin-2, Antigens, Neoplasm, Renal cell carcinoma, Internal medicine, Biomarkers, Tumor, medicine, Humans, In patient, 030212 general & internal medicine, Receptors, Immunologic, Carbonic Anhydrase IX, Carcinoma, Renal Cell, Aged, Neoplasm Staging, Whole blood, Dose-Response Relationship, Drug, Neovascularization, Pathologic, business.industry, Exploratory analysis, Middle Aged, Hypoxia-Inducible Factor 1, alpha Subunit, medicine.disease, Progression-Free Survival, Treatment Outcome, 030220 oncology & carcinogenesis, DEAD Box Protein 58, Female, business, CD8, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2d6a37a4ca7925b11f53a9cc5ae1021Test
https://doi.org/10.1158/1078-0432.ccr-20-1408Test

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PD-L1 Protein Expression on Both Tumor Cells and Macrophages are Associated with Response to Neoadjuvant Durvalumab with Chemotherapy in Triple-negative Breast Cancer

المؤلفون: Kim Blenman, Fahad Shabbir Ahmed, Patricia Gaule, John J. McGuire, David L. Rimm, Lajos Pusztai, Katir K Patel

المصدر: Clin Cancer Res

مصطلحات موضوعية: Adult, 0301 basic medicine, Cancer Research, Durvalumab, Stromal cell, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Antigens, Differentiation, Myelomonocytic, Triple Negative Breast Neoplasms, B7-H1 Antigen, Article, 03 medical and health sciences, Cytokeratin, Lymphocytes, Tumor-Infiltrating, 0302 clinical medicine, Breast cancer, Immune system, Stroma, Antigens, CD, Antineoplastic Combined Chemotherapy Protocols, Biomarkers, Tumor, medicine, Humans, Triple-negative breast cancer, Aged, Cell Proliferation, business.industry, Macrophages, Antibodies, Monoclonal, Immunotherapy, Middle Aged, medicine.disease, Neoadjuvant Therapy, Gene Expression Regulation, Neoplastic, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Cancer research, Female, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::333ffa2e1b4380d458c294bb606f3a2bTest
https://doi.org/10.1158/1078-0432.ccr-20-1303Test

8

Talimogene Laherparepvec and Pembrolizumab in Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (MASTERKEY-232): A Multicenter, Phase 1b Study

المؤلفون: Burak Gumuscu, Kevin J. Harrington, Hoi-Shen Radcliffe, Lillian L. Siu, Wendy Snyder, Danny Rischin, Beatriz Castelo Fernandez, Ezra E.W. Cohen, Jason Chesney, Anthony Kong, Jonathan D. Cheng, Nicolas Mach

المصدر: Clinical Cancer Research, Vol. 26, No 19 (2020) pp. 5153-5161

مصطلحات موضوعية: Adult, Male, Oncology, Cancer Research, medicine.medical_specialty, Drug-Related Side Effects and Adverse Reactions, medicine.medical_treatment, Herpesvirus 1, Human, Pembrolizumab, Antibodies, Monoclonal, Humanized, 03 medical and health sciences, 0302 clinical medicine, Refractory, Internal medicine, Multicenter trial, medicine, Clinical endpoint, Humans, 030212 general & internal medicine, Neoplasm Metastasis, Adverse effect, Aged, ddc:616, Oncolytic Virotherapy, Biological Products, Chemotherapy, Squamous Cell Carcinoma of Head and Neck, business.industry, Middle Aged, medicine.disease, Combined Modality Therapy, Head and neck squamous-cell carcinoma, Progression-Free Survival, 030220 oncology & carcinogenesis, Female, Immunotherapy, Neoplasm Recurrence, Local, Talimogene laherparepvec, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e68d707fa9e943a6b37439bfbf54a5aTest
https://doi.org/10.1158/1078-0432.ccr-20-1170Test

9

High PD-1/PD-L1 Checkpoint Interaction Infers Tumor Selection and Therapeutic Sensitivity to Anti-PD-1/PD-L1 Treatment

المؤلفون: Dae-Jin Lee, Antoine Italiano, Lissete Sánchez-Magraner, Katriona Withers, Richard V. Parry, Shaimaa Elsaid Lashin, Claire L. Baker, James Miles, Andrew G. Watts, Christine E. Edmead, Christopher J. Applebee, Stephen G. Ward, Banafshé Larijani, José I. López, Peter J. Parker, Raj Mehta, Somaia Elsheikh

المصدر: Sanchez-Magraner, L, Miles, J, Baker, C L, Applebee, C, Lee, D-J, Elsheikh, S, Lashin, S, Withers, K, Watts, A, Parry, R, Edmead, C, Lopez, J I, Mehta, R, Italiano, A, Ward, S G, Parker, P J & Larijani, B 2020, ' High PD-1/PD-L1 Checkpoint Interaction Infers Tumor Selection and Therapeutic Sensitivity to Anti-PD-1/PD-L1 Treatment ', Cancer Research, vol. 80, no. 19, pp. 4244-4257 . https://doi.org/10.1158/0008-5472.CAN-20-1117Test

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Cancer Research, Lung Neoplasms, medicine.medical_treatment, Programmed Cell Death 1 Receptor, B7-H1 Antigen, 03 medical and health sciences, 0302 clinical medicine, Immune system, Carcinoma, Non-Small-Cell Lung, PD-L1, Fluorescence Resonance Energy Transfer, medicine, Humans, Molecular Targeted Therapy, Carcinoma, Renal Cell, Melanoma, Aged, Cluster of differentiation, biology, business.industry, Reproducibility of Results, Cancer, Immunosuppression, Middle Aged, medicine.disease, Kidney Neoplasms, Immune checkpoint, 3. Good health, Treatment Outcome, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Cancer research, biology.protein, Female, business, CD80

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::372c5ebcf055e5084c32083fad16bb71Test
https://doi.org/10.1158/0008-5472.can-20-1117Test

10

Macrophage HIF-1α Is an Independent Prognostic Indicator in Kidney Cancer

المصدر: Clin Cancer Res

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Cancer Research, In situ hybridization, Nephrectomy, Article, Metastasis, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, Tumor-Associated Macrophages, Von Hippel–Lindau tumor suppressor, Basic Helix-Loop-Helix Transcription Factors, Biomarkers, Tumor, medicine, Humans, Genes, Tumor Suppressor, RNA-Seq, Carcinoma, Renal Cell, Aged, Neoplasm Staging, Retrospective Studies, Aged, 80 and over, biology, business.industry, Middle Aged, Hypoxia-Inducible Factor 1, alpha Subunit, Prognosis, medicine.disease, Survival Analysis, Kidney Neoplasms, Gene Expression Regulation, Neoplastic, Clear cell renal cell carcinoma, 030104 developmental biology, MRNA Sequencing, Oncology, Chemotherapy, Adjuvant, 030220 oncology & carcinogenesis, Disease Progression, biology.protein, Cancer research, Immunohistochemistry, Female, Neoplasm Grading, Single-Cell Analysis, business, Kidney cancer, CD163

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80af84e280d3540222d6d04705d792c6Test
https://doi.org/10.1158/1078-0432.ccr-19-3890Test

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