Juvenile Idiopathic Arthritis – Changing Times, Changing Terms, Changing Treatments
| العنوان: | Juvenile Idiopathic Arthritis – Changing Times, Changing Terms, Changing Treatments |
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| المؤلفون: | Susan Shenoi |
| المصدر: | Pediatrics In Review. 38:221-232 |
| بيانات النشر: | American Academy of Pediatrics (AAP), 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | musculoskeletal diseases, medicine.medical_specialty, Anti-nuclear antibody, Childhood arthritis, Arthritis, Diagnosis, Differential, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Humans, Rheumatoid factor, 030212 general & internal medicine, Child, skin and connective tissue diseases, 030203 arthritis & rheumatology, business.industry, Prognosis, medicine.disease, Arthritis, Juvenile, Rheumatology, Pigmented villonodular synovitis, Macrophage activation syndrome, Pediatrics, Perinatology and Child Health, Physical therapy, business, Juvenile rheumatoid arthritis |
| الوصف: | 1. Susan Shenoi, MBBS, MS* 1. *Department of Pediatrics, Division of Rheumatology, University of Washington School of Medicine & Seattle Children’s Hospital, Seattle, WA * Abbreviations: ALT: : alanine aminotransferase ANA: : antinuclear antibody AST: : aspartate aminotransferase CARRA: : Childhood Arthritis and Rheumatology Research Alliance CBC: : complete blood cell CRP: : C-reactive protein DMARD: : disease-modifying antirheumatic drug ERA: : enthesitis-related arthritis ESR: : erythrocyte sedimentation rate FDA: : Food and Drug Administration HLA: : human leukocyte antigen IAS: : intraarticular corticosteroid injection IL: : interleukin ILAR: : International League of Associations for Rheumatology IV: : intravenous JIA: : juvenile idiopathic arthritis MAS: : macrophage activation syndrome NSAID: : nonsteroidal anti-inflammatory drug PVNS: : pigmented villonodular synovitis RF: : rheumatoid factor SJIA: : systemic juvenile idiopathic arthritis TMJ: : temporomandibular joint TNF: : tumor necrosis factor The management of juvenile idiopathic arthritis (JIA) has changed radically over the last few decades. This article provides an update on identification of JIA, complications of the condition, and common management strategies to help practitioners treat affected children in conjunction with other specialists as part of a multidisciplinary team. After completing this article, readers should be able to: 1. Recognize the clinical findings associated with the various categories of juvenile idiopathic arthritis (JIA). 2. Recognize the laboratory findings associated with the different categories of JIA and its complications. 3. Formulate a differential diagnosis for children with joint pain. 4. Recognize the long-term complications associated with JIA. 5. Plan the appropriate management of JIA while recognizing adverse effects of some therapies. Arthritis is a common cause of disability in childhood. In children, the condition previously was known as juvenile chronic arthritis or juvenile rheumatoid arthritis. Currently, the preferred name for childhood arthritis is juvenile idiopathic arthritis (JIA) because this term denotes the idiopathic or unknown cause of the condition. The exact incidence and prevalence of JIA is unknown and likely varies across the world. The estimated incidence and prevalence of JIA in the United States is approximately 14 per 100,000 children (95% confidence interval: 10–18) and 113 per 100,000 (95% confidence interval: 55–155), respectively. (1) JIA is believed to have a multifactorial etiology, with both genetic and nongenetic (ie, environmental) contributing causes. Due to the paucity of practicing pediatric rheumatologists, pediatricians or family practice physicians often are “on the front line” for initial identification and treatment of JIA. This article focuses on key points for diagnosis and initial evaluation of JIA and provides an overview of treatment. According … |
| تدمد: | 1526-3347 0191-9601 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f47aacb49183671a127c4f6478061fcTest https://doi.org/10.1542/pir.2016-0148Test |
| رقم الانضمام: | edsair.doi.dedup.....7f47aacb49183671a127c4f6478061fc |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15263347 01919601 |
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