Vitamin A Deficiency Due to Selective Eating as a Cause of Blindness in a High-Income Setting
| العنوان: | Vitamin A Deficiency Due to Selective Eating as a Cause of Blindness in a High-Income Setting |
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| المؤلفون: | Michelangelo Fiorentino, Angela Rizzello, R. Bergamaschi, Silvia Martini, Ilaria Corsini, Benedetta Romanin, Sara Grandi |
| المساهمون: | Martini, Silvia, Rizzello, Angela, Corsini, Ilaria, Romanin, Benedetta, Fiorentino, Michelangelo, Grandi, Sara, Bergamaschi, Rosalba |
| المصدر: | Pediatrics. 141:S439-S444 |
| بيانات النشر: | American Academy of Pediatrics (AAP), 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | 0301 basic medicine, Vitamin, Pediatrics, medicine.medical_specialty, Opportunistic infection, Anemia, Urinary Bladder, Pediatrics, Perinatology and Child Health, vitamin A deficiency, VAD, blindness, high-income countries, restrictive diet, Opportunistic Infections, Blindness, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, 030225 pediatrics, medicine, Humans, Growth Disorders, 030109 nutrition & dietetics, Vitamin A Deficiency, business.industry, Developed Countries, Childhood blindness, Retinol, Feeding Behavior, Micronutrient, medicine.disease, Mother-Child Relations, Diet, Vitamin A deficiency, Italy, chemistry, Child, Preschool, Pediatrics, Perinatology and Child Health, Income, Female, business, Developed country |
| الوصف: | Vitamin A is a fat-soluble micronutrient involved in the regulation of several physiologic functions, such as visual acuity, epithelial tissue integrity, immune response, and gene expression, thus playing a crucial role in childhood growth and development. Although vitamin A deficiency (VAD) in resource-limited settings is still an actual issue and represents the leading cause of preventable childhood blindness, its occurrence in high-income countries is rare, although possibly underdiagnosed because of its nonspecific early manifestations. A good awareness of VAD symptoms and risk factors could aid its early diagnosis, which is fundamental to undertake a prompt treatment and to prevent ocular complications. Nevertheless, the role of restrictive dietary habits, increasingly common in developed countries, is often overlooked in infants and children. We present a case of VAD with permanent ocular sequelae in a 5-year-old girl from a high-income country. In the case described, VAD ensued from a highly restricted diet, mainly limited to oat milk, which had been followed for more than 2 years. This child presented with ocular symptoms, opportunistic infection, anemia, poor growth, and a diffuse squamous metaplasia of the bladder; after commencing retinol supplementation, a gradual healing of clinical VAD manifestations occurred, with the exception of the ocular sequelae, which resulted in irreversible visual loss. |
| وصف الملف: | STAMPA |
| تدمد: | 1098-4275 0031-4005 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::165b85a81d20e71b9469ca3a10a481a3Test https://doi.org/10.1542/peds.2016-2628Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....165b85a81d20e71b9469ca3a10a481a3 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10984275 00314005 |
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